2011

2011 (論文)

  1. Sano K, Temma T, Azuma T, Nakai R, Narazaki M, Kuge Y, Saji H.
    A pre-targeting strategy for MR imaging of functional molecules using dendritic Gd-based contrast agents
    Mol. Imaging Biol. 13(6) 1196-1203 (2011)
  2. Arimitsu K, Kajimoto T, Kimura H, Ono M, Ozeki M, Node M, Ohmomo Y, Saji H, Yamashita M.
    Alternative synthesis of radioiodinated trisaccharide derivatives, 2-(4- 125iodophenyl)ethyl 2-acetamido-2-deoxy-β-d-glucopyranosyl- (1→2)-α-d-mannopyranosyl-( 1→6)-β-d-glucopyranoside, and preparation of its analogs having different lengths of alkyl chains instead of ethyl group: Acceptor substrates of n-acetylglucosaminyltransferase v for in vivo imaging
    Heterocycles 83(12) 2779-2802 (2011)
  3. Harada N, Kimura H, Ono M, Mori D, Ohmomo Y, Kajimoto T, Kawashima H, Saji H.
    Effective synthesis of 99mTc tricarbonyl complexes by microwave heating
    J. Organomet. Chem. 696(23) 3745-3749 (2011)
  4. Watanabe H, Ono M, Kimura H, Kagawa S, Nishii R, Fuchigami T, Haratake M, Nakayama M, Saji H.
    A dual fluorinated and iodinated radiotracer for PET and SPECT imaging of β-amyloid plaques in the brain
    Bioorg. Med. Chem. Lett. 21(21) 6519-6522 (2011)
  5. Ueda M, Kudo T, Mutou Y, Umeda I.O, Miyano A, Ogawa K, Ono M, Fujii H, Kizaka-Kondoh S, Hiraoka M, Saji H.
    Evaluation of [125I]IPOS as a molecular imaging probe for hypoxia-inducible factor-1-active regions in a tumor: Comparison among single-photon emission computed tomography/X-ray computed tomography imaging, autoradiography, and immunohistochemistry
    Cancer Sci. 102(11) 2090-2096 (2011)
  6. Shimizu Y, Temma T, Sano K, Ono M, Saji H.
    Development of membrane type-1 matrix metalloproteinase-specific activatable fluorescent probe for malignant tumor detection
    Cancer Sci. 102(10) 1897-1903 (2011)
  7. Makino A, Harada H, Okada T, Kimura H, Amano H, Saji H, Hiraoka M, Kimura S.
    Effective encapsulation of a new cationic gadolinium chelate into apoferritin and its evaluation as an MRI contrast agent
    Nanomedicine: NBM 7(5) 638-646 (2011)
  8. Kudo T, Ueda M, Konishi H, Kawashima H, Kuge Y, Mukai T, Miyano A, Tanaka S, Kizaka-Kondoh S, Hiraoka M, Saji H.
    PET imaging of hypoxia-inducible factor-1-active tumor cells with pretargeted oxygen-dependent degradable streptavidin and a novel 18F-labeled biotin derivative
    Mol. Imaging Biol. 13(5) 1003-1010 (2011)
  9. Hagimori M, Mizuyama N, Yokota K, Morinaga O, Yamaguchi Y, Saji H, Tominaga Y.
    Synthesis of fluorescent pyrrolo[3,4-b]quinolizine derivatives and evaluation as a protein-labeling probe
    Heterocycles 83(9) 1983-1988 (2011)
  10. Mukai T, Hagimori M, Arimitsu K, Katoh T, Ukon M, Kajimoto T, Kimura H, Magata Y, Miyoshi E, Taniguchi N, Node M, Saji H.
    Synthesis and evaluation of a radioiodinated trisaccharide derivative as a synthetic substrate for a sensitive N-acetylglucosaminyltransferase v radioassay
    Bioorg. Med. Chem. 19(14) 4312-4321 (2011)
  11. Cui M, Ono M, Kimura H, Liu B, Saji H.
    Novel quinoxaline derivatives for in vivo imaging of β-amyloid plaques in the brain
    Bioorg. Med. Chem. Lett. 21(14) 4193-4196 (2011)
  12. Cui M, Ono M, Kimura H, Liu B, Saji H.
    Synthesis and evaluation of benzofuran-2-yl(phenyl)methanone derivatives as ligands for β-amyloid plaques
    Bioorg. Med. Chem. 19(13) 4148-4153 (2011)
  13. Matsumura K, Ono M, Hayashi S, Kimura H, Okamoto Y, Ihara M, Takahashi R, Mori H, Saji H.
    Phenyldiazenyl benzothiazole derivatives as probes for in vivo imaging of neurofibrillary tangles in Alzheimer’s disease brains
    Med. Chem. Commun. 2(7) 596-600 (2011)
  14. Hirata K, Kuge Y, Yokota C, Harada A, Kokame K, Inoue H, Kawashima H, Hanzawa H, Shono Y, Saji H, Minematsu K, Tamaki N.
    Gene and protein analysis of brain derived neurotrophic factor expression in relation to neurological recovery induced by an enriched environment in a rat stroke model
    Neurosci. Lett. 495(3) 210-215 (2011)
  15. Ono M, Hayashi S, Matsumura K, Kimura H, Okamoto Y, Ihara M, Takahashi R, Mori H, Saji H.
    Rhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer’s brains
    ACS Chem. Neurosci. 2(5) 269-275 (2011)
  16. Masuda R, Oishi S, Ohno H, Kimura H, Saji H, Fujii N.
    Concise site-specific synthesis of DTPA-peptide conjugates: Application to imaging probes for the chemokine receptor CXCR4
    Bioorg. Med. Chem. 19(10) 3216-3220 (2011)
  17. Ono M, Saji H.
    SPECT Imaging Agents for Detecting Cerebral beta-Amyloid Plaques.
    Int. J. Mol. Imaging 2011 543267 (2011) Review.
  18. Ono M, Cheng Y, Kimura H, Cui M, Kagawa S, Nishii R, Saji H.
    Novel 18F-labeled benzofuran derivatives with improved properties for positron emission tomography (PET) imaging of β-amyloid plaques in Alzheimer’s brains
    J. Med. Chem. 54(8) 2971-2979 (2011)
  19. Cui M, Ono M, Kimura H, Liu B, Saji H.
    Synthesis and structure-affinity relationships of novel dibenzylideneacetone derivatives as probes for ß-Amyloid Plaques
    J. Med. Chem. 54(7) 2225-2240 (2011)
  20. Cui M, Ono M, Kimura H, Kawashima H, Liu B.L, Saji H.
    Radioiodinated benzimidazole derivatives as single photon emission computed tomography probes for imaging of β-amyloid plaques in Alzheimer’s disease
    Nucl. Med. Biol. 38(3) 313-320 (2011)
  21. Shimizu S, Atsumi R, Nakazawa T, Izumi T, Sudo K, Okazaki O, Saji H.
    Ticlopidine-induced hepatotoxicity in a GSH-depleted rat model
    Arch. Toxicol. 85(4) 347-353 (2011)
  22. Shono Y, Yokota C, Kuge Y, Kido S, Harada A, Kokame K, Inoue H, Hotta M, Hirata K, Saji H, Tamaki N, Minematsu K.
    Gene expression associated with an enriched environment after transient focal ischemia
    Brain Res. 1376 60-65 (2011)
  23. Hagimori M, Mizuyama N, Yamaguchi Y, Saji H, Tominaga Y.
    A novel small molecule fluorescent sensor for Zn2+ based on pyridine-pyridone scaffold
    Talanta83(5) 1730-1735 (2011)
  24. Cui M, Ono M, Kimura H, Liu B.L., Saji H.
    Synthesis and biological evaluation of indole-chalcone derivatives as β-amyloid imaging probe
    Bioorg. Med. Chem. Lett. 21(3) 980-982 (2011)
  25. Ueda M, Iida Y, Yoneyama T, Kawai T, Ogawa M, Magata Y, Saji H.
    In vivo relationship between thalamic nicotinic acetylcholine receptor occupancy rates and antiallodynic effects in a rat model of neuropathic pain: Persistent agonist binding inhibits the expression of antiallodynic effects
    Synapse65(1) 77-83 (2011)
  26. Ono M, Watanabe H, Watanabe R, Haratake M, Nakayama M, Saji H.
    Diphenylpropynone derivatives as probes for imaging β-amyloid plaques in Alzheimer’s brains
    Bioorg. Med. Chem. Lett. 21(1) 117-120 (2011)

 

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