publication

• Thermodynamic analyses of amino acid residues at the interface of an antibody B2212A and its antigen roundabout homolog 1.
  Yui A, Akiba H, Kudo S, Nakakido M, Nagatoishi S, Tsumoto K
  J. Biochem. 162, 255-258 (2017)
• Use of SpyTag/SpyCatcher to construct bispecific antibodies that target two epitopes of a single antigen.
  Yumura K, Akiba H, Nagatoishi S, Kusano-Arai O, Iwanari H, Hamakubo T, Tsumoto K
  J. Biochem. 162, 203-210 (2017)
• Improved Brain Expression of Anti-Amyloid β scFv by Complexation of mRNA Including a Secretion Sequence with PEG-based Block Catiomer.
  Perche F, Uchida S, Akiba H, Lin CY, Ikegami M, Dirisala A, Nakashima T, Itaka K, Tsumoto K, Kataoka K
  Curr. Alzheimer Res. 14, 295-302 (2017)
• Selective Sensing of Tyrosine Phosphorylation in Peptides Using Terbium(III) Complexes.
  Sumaoka J, Akiba H, Komiyama M
  Int. J. Anal. Chem. 2016, 3216523 (2016) (Review)
• Thermodynamics of antibody-antigen interaction revealed by mutation analysis of antibody variable regions.
  Akiba H, Tsumoto K
  J. Biochem. 158, 1-13 (2015) (Review)
• Click conjugation of a binuclear terbium(III) complex for real-time detection of tyrosine phosphorylation.
  Akiba H, Sumaoka J, Tsumoto K, Komiyama M
  Anal. Chem. 87, 3834-3840 (2015)
• Conjugation-free, visual, and quantitative evaluation of inhibitors on protein tyrosine kinases and phosphatases with a luminescent Tb(III) complex.
  Akiba H, Sumaoka J, Hamakubo T, Komiyama M
  Anal. Bioanal. Chem. 406, 2957-2964 (2014)
• Binuclear terbium(III) complex as a probe for tyrosine phosphorylation.
  Akiba H, Sumaoka J, Komiyama M
  Chem. Eur. J. 16, 5018-5025 (2010)
• Selective detection of phosphotyrosine in the presence of various phosphate-containing biomolecules with the aid of a terbium(III) complex.
  Akiba H, Sumaoka J, Komiyama M
  Chembiochem 10, 1773-1776 (2009)

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