Chemical biology based on forward/reverse chemical genetics is a new research paradigm that accelerates drug development and the functional analysis of genes and proteins. Diversity of small molecules is one of the most important points to facilitate the success of chemical biology. As such, we have been screening two types of chemical libraries: a natural products library and a synthetic chemical library. After identifying bioactive small molecules, their modes of actions and targets are investigated using a chemical biology-based approach.
Natural Product Chemistry, Chemical Biology, Chemical Genomics, Molecular Target Drugs, Chemoinformatics, Bioinformatics, Chemical Communications, Regenerative Medicine, Metabolome Analysis, Medicinal Chemistry, Translational Research, Natural Medicine, Microorganisms, Medicinal Plant, Kampo Medicines, etc