<研究紹介> |
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リズムに乗って生きる/脳の時計/時計と遺伝子/身体の時計/分析から統合へ:時計研究は21世紀のライフサイエンスを切り開く |
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研究の目標/どんな研究をするのか |
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Discovery of mammalian Period genes |
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Restoration of Drosophila arrhythmic
mutant by incorporation of mammalian Period |
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Discovery of arrhythmic mCry1/mCry2-double
knockout mice and the recovery by the brain transplantation |
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Protein level regulation of mPer proteins |
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Core clock loop of clock genes is
universal among mammalian cells |
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Core clock regulates clock controlled
genes |
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Circadian clock regulates cell cycle |
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Synchronization of cellular clock
in the supachiasmatic nucleus demonstrated by the
single cell analysis of cellular rhythms by the luciferase
genetransgenic mice |
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SCN central clock regulates peripheral
rhythms by sympathetic adrenal routes |
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Real time monitoring of melatonin
by the lintracerebral microdialysis probe |
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Development of the real time monitoring
system of the gene expression in the brain in freely
moving mice |
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Recent view |
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<システムバイオロジー分野> |
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<ご案内> |
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修士課程/博士課程(博士後期過程編入学) |
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