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-------  Kiyoshi  TOMIOKA  laboratory  ------- Intelligent excitement is of primary importance. Creation and discovery are our goals. Development of new synthetic reactions and discovery of new molecules, fundamental leading concept are of our primary interests. OUR CHEMISTRY : Synthetic methodology Catalytic asymmetric reaction Molecular architecture Bioorganic chemistry of antitumor molecule

Professor Kiyoshi Tomioka April 2009 at Kamogawa  2008  2007  2006  2005   2004 Daimonji (2003 Daimonji click here) Research Members Publications Lectures Gallery Useful Links

Hot News Efficient Chiral N-Heterocyclic Carbene/Copper(I)-Catalyzed Asymmetric Allylic Arylation with Aryl Grignard Reagents. Khalid B. Selim, Yasumasa Matsumoto, Ken-ichi Yamada, and Kiyoshi Tomioka Angew. Chem. Int. Ed. 2009, 48 (46), 8733-8735. was introduced in SYNFACTS issue 01/10. Steric Tuning of the Amidomonophosphane-Rhodium(I) Catalyst in Asymmetric Addition of Arylboroxines to N-Phosphinoyl Aldimines. Xinyu Hao, Masami Kuriyama, Qian Chen, Yasutomo Yamamoto, Ken-ichi Yamada, and Kiyoshi Tomioka Org. Lett. 2009, 11 (19), 4470-4473. was introduced in SYNFACTS issue 01/10. Efficient Chiral N-Heterocyclic Carbene/Copper(I)-Catalyzed Asymmetric Allylic Arylation with Aryl Grignard Reagents. Khalid B. Selim, Yasumasa Matsumoto, Ken-ichi Yamada, and Kiyoshi Tomioka Angew. Chem. Int. Ed. 2009, 48 (46), 8733-8735. was selected as an Angewandte Chemie Hot Paper. Total Synthesis of (-)-Lycorine and (-)-2-epi-Lycorine by Asymmetric Conjugate Addition Cascade. Ken-ichi Yamada, Mitsuaki Yamashita, Takaaki Sumiyoshi, Katsumi Nishimura, and Kiyoshi Tomioka Org. Lett. 2009, 11(7), 1631-1633. was introduced in SYNFACTS issue 10/09. Tin-free Radical Addition of Acyloxymethyl to Imines. Ken-ichi Yamada, Mayu Nakano, Masaru Maekawa, Tito Akindele, and Kiyoshi Tomioka Org. Lett. 2008, 10(17), 3805-3808. was introduced in SYNFACTS issue 12/08. Prof. Ken-ichi Yamada was awarded The Pharmaceutical Society of Japan Award for Young Scientists '07 "Development of Direct Generation of Carbon-Centered Radicals Via Cleavage of C-H Bond and their Reactions" Mechanistic Aspects of Thiyl Radical-Promoted Acyl Radical Cyclization of Formylenoate – Cyclization versus Oxidation. Kazuya Yoshikai, Tomoharu Hayama, Katsumi Nishimura, Ken-Ichi Yamada, and Kiyoshi Tomioka, Chem. Pharm. Bull. 2005, 53(5), 586-588. Cover figure of the issue Direct Aminoalkylation of Cycloalkanes through Dimethylzinc-Initiated Radical Process. Ken-ichi Yamada, Yasutomo Yamamoto, Masaru Maekawa, Jingbo Chen, and Kiyoshi Tomioka Tetrahedron Lett. 2004, 45(35), 6595-6597. Cover Figure of the issue

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ISPC08: The First International Symposium on Process Chemistry July 28-30, 2008, Kyoto

KOREA-JAPAN YOUNG SCIENTISTS JOINT SYMPOSIUM July 27-30, 2003

Graduate School of Pharmaceutical Sciences,
Kyoto University, Yoshida, Sakyou-ku, Kyoto 606-8501