Uchiyama R, Yonehara S, and Tsutsui H. (2013).
Identification of a novel type 2 innate immunocyte with the ability to enhance IgE production.
Immunol, doi: 10.4049/jimmunol.1203059.

Fukuoka A, Futatsugi-Yumikura S, Takahashi S, Kazama H, Iyoda T, Yoshimoto T, Inaba K, Nakanishi K and Yonehara S. (2013).
Identification of a novel type 2 innate immunocyte with the ability to enhance IgE production.
Int Immunol, doi:10.1093/intimm/dxs160.

Takahashi S, Futatsugi-Yumikura S, Fukuoka A, Yoshimoto T, Nakanishi K and Yonehara S. (2013).
Fas deficiency in mice with the Balb/c background induces blepharitis with allergic inflammation and hyper-IgE production in conjunction with severe autoimmune disease.
Int Immunol, doi:10.1093/intimm/dxs109.

Nakanishi Y, Seno H, Fukuoka A, Ueo T, Yamaga Y, Maruno T, Nakanishi N, Kanda K, Komekado H, Kawada M, Isomura A, Kawada K, Sakai Y, Yanagita M, Kageyama R, Kawaguchi Y, Taketo MM, Yonehara S and Chiba T. (2012).
Dclk1 Distinguishes between Tumor and Normal Stem Cells in the intestine.
Nat Genet, 45, 98-103.

Kikuchi M, Kuroki S, Kayama M, Sakaguchi S, Lee KK and Yonehara S. (2012).
Protease Activity of Procaspase-8 Is Essential for Cell Survival by Inhibiting Both Apoptotic and Nonapoptotic Cell Death Dependent on Receptor-Interacting Protein Kinase 1 (RIP1) and RIP3.
J Boil Chem, 287, 41165-73.

Lee KK and Yonehara S. (2012).
Identification of mechanism that couples multisite phosphorylation of Yes-associated protein (YAP) with transcriptional coactivation and regulation of apoptosis.
J Biol Chem, 287, 9568-78

Gao Y, Kazama H and Yonehara S. (2012).
Bim regulates B-cell receptor-mediated apoptosis in the presence of CD40 signaling in CD40-pre-activated splenic B cells differentiating into plasma cells.
Int Immunol, 24, 283-92.

Nakatsumi H, and Yonehara S. (2010).
Identification of functional regions defining different activity between caspase-3 and caspase-7 within cells.
J Biol Chem, 285, 25418-25425.

Miyake Y, Nakamura M, Nabetani A, Shimamura S, Tamura M, Yonehara S, Saito M, and Isikawa F. (2009).
RPA-like Mammalian Ctc1-Stn1-Ten1 Complex Binds to Single-Stranded DNA and Protects Telomeres Independently of the Pot1 Pathway.
Mol Cell, 36, 193-206.

Kiriyama M, Kobayashi Y, Saito M, Ishikawa F and Yonehara S. (2009).
Interaction of FLASH with arsenite resistance protein 2 is involved in cell cycle progression at S phase.
Mol Cell Biol, 29, 4742-4756.

Kobayashi Y, and Yonehara, S. (2009).
Novel cell death by downregulation of eEF1A1 expression in tetraploids.
Cell Death and Differentiation , 16, 139-150.

Moriyama H, and Yonehara S. (2007).
Rapid up-regulation of c-FLIP expression by BCR signaling through the PI3K/Akt pathway inhibits simultaneously induced Fas-mediated apoptosis in murine B lymphocytes.
Immunol Lett, 109, 36-46.

Yamamoto T., Ebisuya M., Ashida F., Okamoto K., Yonehara, S., and Nishida E. (2006).
Continuous ERK activation downregulates antiproliferative genes throughout G1 phase to allow cell-cycle progression.
Curr Biol, 16, 1171-1182.

Okamoto K, Fujisawa J, Reth M, and Yonehara S. (2006)
Human T-cell leukemia virus type I oncoprotein Tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-κB.
Genes Cells, 11, 177-191.

Ohgushi M, Kuroki S, Fukamachi H, O'Reilly LA, Kuida K, Strasser A, and Yonehara S. (2005).
Transforming growth factor β-dependent sequential activation of Smad, Bim, and caspase-9 mediates physiological apoptosis in gastric epithelial cells.
Mol Cell Biol, 25, 10017-10028.

Nakagiri, S., Murakami, A., Takada, S., Akiyama, T. and Yonehara, S. (2005).
Viral FLIP enhances Wnt signaling downstream of stabilized beta-catenin, leading to control of cell growth.
Mol Cell Biol, 25, 9249-9258.

Watanabe, K., Okamoto, K., and Yonehara, S. (2005)
Sensitization of osteosarcoma cells to death receptor-mediated apoptosis by HDAC inhibitors through down-regulation of cellular FLIP.
Cell Death Differ, 12, 10-18 .

Mai , A., Jung, S.-K., and Yonehara, S. (2004)
hDKIR, a human homologue of the Drosophila Kelch protein, involved in a ring-like structure.
Exp Cell Res, 300, 72-83.

Fukumoto, N., Shimaoka, T., Fujimura, H., Sakoda, S., Tanaka, M., Kita, T., and Yonehara, S. (2004)
Critical roles of CXC chemokine ligand 16/scavenger receptor that binds phosphatidylserine and oxidized lipoprotein in the pathogenesis of both acute and adoptive transfer experimental autoimmune encephalomyelitis.
J Immunol, 173, 1620-1627.

Yajima, N., Sakamaki, K., and Yonehara, S. (2004)
Age-related thymic involution is mediated by Fas on thymic epithelial cells.
Int Immunol, 16, 1027-1035.

Shimaoka, T., Nakayama, T., Hieshima K., Kume, N., Fukumoto, N., Minami, M., Hayashida, K., Kita, T., Yoshie, O., and Yonehara, S. (2004)
Accelerated Publications: Chemokines generally exhibit scavenger receptor activity through their receptor-binding domain.
J Biol Chem, 279, 26807-26810.

Shimaoka, T., Nakayama, T., Fukumoto, N., Kume, N., Takahashi, S., Yamaguchi, J., Minami, M., Hayashida, K., Kita, T., Ohsumi, J., Yoshie, O., and Yonehara, S. (2004)
Cell surface-anchored SR-PSOX/ CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells.
J Leukoc Biol 75, 267-274.

Shimaoka, T., Nakayama, T., Kume, N., Takahashi, S., Yamaguchi, J., Minami, M., Hayashida, K., Kita, T., Ohsumi, J., Yoshie, O., and Yonehara, S. (2003)
Cutting Edge: SR-PSOX/CXC Chemokine Ligand 16 Mediates Bacterial Phagocytosis by APCs Through its Chemokine Domain.
J Immunol 171, 1647-1651.

Sakata, S., Sakamaki, K., Watanabe, K., Nakamura, N., Toyokuni, S., Nishimune, Y. , Mori, C., Yonehara, S. (2003)
Involvement of death receptor Fas in germ cell degeneration in gonads of Kit-deficient Wv/Wv mutant mice.
Cell Death Differ 10, 676-686.

Yonehara, S. (2002)
Death receptor Fas and autoimmune disease: from the original generation to therapeutic application of agonistic anti-Fas monoclonal antibody.
Cytokine Growth Factor Rev 13, 393-402.

Sakamaki, K., Inoue, T., Asano, M., Sudo, K., Kazama, H., Sakagami, J., Sakata, S., Ozaki, M., Nakamura, S., Toyokuni,S., Osumi,N., Iwakura, Y., and Yonehara, S. (2002)
Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart.
Cell Death Differ 9, 1196-1206.

Lee, K.K., and Yonehara, S. (2002)
Phosphorylation and dimerization regulate nucleocytoplasmic shuttling of mammalian STE20-like kinase (MST) .
J Biol Chem 277, 12351-12358.

Lee, K.K., Ohyama, T., Yajima, N., Tsubuki, S., and Yonehara, S. (2001)
MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation.
J Biol Chem 276, 19276-19285.

Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Sawamura, T., Kita, T., and Yonehara, S. (2001)
Lectin-like oxidized low density lipoprotein receptor-1 (LOX-1) supports cell adhesion to fibronectin.
FEBS Letters 504, 65-68.

Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Sawamura, T., Kita, T., and Yonehara, S. (2001)
LOX-1 supports adhesion of gram-positive and gram-negative bacteria.
J Immunol 166, 5108-5114.

Murakawa, M., Jung, S.K., Iijima, K., and Yonehara, S. (2001)
Apoptosis-Inducing Protein, AIP, from parasite-infected fish induced apoptosis in mammalian cells by two different molecular mechanisms.
Cell Death Differ 8, 298-307.

Shimaoka, T., Kume, N., Minami, M., Hayashida, K., Kataoka, H., Kita, T., and Yonehara, S. (2000)
Molecular cloning of a novel scavenger receptor for oxidized low density lipoprotein, SR-PSOX, on macrophages.
J Biol Chem 275, 40663-40666.

OhYama, T., Tsukumo, S., Yajima, N., Sakamaki, K., and Yonehara, S. (2000)
Reduction of thymocyte numbers in transgenic mice expressing viral FLICE-inhibitory protein in a Fas-independent manner.
Microbiol Immunol 44, 289-297.

Ichikawa, K., Yoshida-Kato, H., Ohtsuki, M., Ohsumi, J., Yamaguchi, J., Takahashi, S., Tani, Y., Watanabe, M., Shiraishi, A., Nishioka, K., Yonehara, S. and Serizawa, N. (2000)
A novel murine anti-human Fas mAb which mitigates lymphadenopathy without hepatotoxicity.
Int Immunol 12, 555-562.

Jung, S.K., Mai, A., Iwamoto, M., Arizono, N., Fujimoto, D., Sakamaki, K., and Yonehara, S. (2000)
Purification and cloning of an apoptosis-inducing protein derived from fish infected with Anisakis simplex, a causative nematode of human Anisakiasis.
J Immunol 165, 1491-1497.

Kazama, H., and Yonehara, S.. (2000)
Oncogenic K-Ras and basic FGF prevent Fas-mediated apoptosis in fibroblasts through activation of MAP kinase.
J Cell Biol 148, 557-566.

Kimura, T., Imai, Y., and Yonehara, S. (1999)
Reply: Searching for FLASH domains.
Nature 401, 662-663.

Imai, Y., Kimura, T., Murakami, A., Yajima, N., Sakamaki, K., and Yonehara, S. (1999)
The CED-4-homologous protein FLASH is involved in Fas-mediated activation of caspase-8 during apoptosis.
Nature 398, 777-785.

Inazawa, Y., and Yonehara, S. (1999)
Fas-induced in vivo apoptosis in bone marrow: Anti-Fas mAb-induced elimination and successive proliferation of Fas-expressing cells especially those of myeloid lineage.
Cell Struct Funct 24, 151-159.

Yonehara, S. (1999)
Effects of anti-Fas antibodies on lymphocytes and other organs: Preparation of original and new monoclonal antibodies and amelioration of systemic autoimmune disease.
Intern Rev Immunol 18, 329-345.

Tsukumo, S., and Yonehara, S. (1999)
Requirement of cooperative functions of two repeated death effector domains in caspase-8 and in MC159 for induction and inhibition of apoptosis, respectively.
Genes Cells 4, 541-549.

Sakamaki, K., Tsukumo, S., and Yonehara, S. (1998)
Molecular cloning and characterization of mouse caspase-8.
Eur J Biochem 253, 399-405.

Lee, K.K., Murakawa, M., Takahasi, S., Tsubuki, S., Kawashima, S., Sakamaki, K., and Yonehara, S. (1998)
Purification, Molecular Cloning and Characterization of TRP32, a Novel Thioredoxin-Related Mammalian Protein of 32 kDa.
J Biol Chem 273, 19160-19166.

Lee, K.K., Murakawa, M., Nishida, E., Tsubuki, S., Kawashima, S., Sakamaki, K., and Yonehara, S. (1998)
Proteolytic activation of MST/Krs, STE20-related protein kinase, by caspase during apoptosis.
Oncogene 16, 3029-3037.

Kuroda, S., Fukata, M., Nakagawa, M., Fujii, K., Nakamura, T., Ookubo, T., Izawa, I., Nagase, T., Nomura, N., Tani, H., Shoji, I., Matsuura, Y., Yonehara, S., and Kaibuchi, K. (1998)
Participation of IQGAP1, a target of the small GTPase Cdc42 and Rac1, in the regulation of E-cadherin-mediated cell-cell adhesion.
Science 281, 832-835.

Yonehara, S., and Nakamachi, Y. (1998)
CD95 Workshop panel report.
In Leucocyte Typing VI: White Cell Differentiation Antigens, T. Kishimoto, H. Kikutani et al., ed. (New York, NY: Garland publishing, Inc.), pp804-806.

Nishimura-Morita, Y., Nose, M., Inoue, T., and Yonehara, S. (1997)
Amelioration of systemic autoimmune disease by the stimulation of apoptosis-promoting receptor Fas with anti-Fas mAb.
Int Immunol 9, 1793-1799.

Nishimura, Y., Hirabayashi, Y., Matsuzaki, Y., Musette, P., Ishii, A., Nakauchi, H., Inoue, T., and Yonehara, S. (1997)
In vivo analysis of Fas antigen-mediated apoptosis: effects of agonistic anti-mouse Fas mAb on thymus, spleen and liver.
Int Immunol 9, 307-316.

Fadeel, B., Thorpe, C.J., Yonehara, S., and Chiodi, F. (1997)
Anti-Fas IgG1 antibodies recognizing the same epitope of Fas/APO-1 mediate dirrernt biological effects in vitro.
Int Immunol 9, 201-209.

Sakamaki, K., Yoshida, H., Nishimura, Y., Nishikawa, S., Manabe, N., and Yonehara, S. (1997)
Involvement of Fas antigen in ovarian follicular atresia and luteolysis.
Mol Rep Dev 47, 11-18.

Kishi, S., Saijo, S., Arai, M., Karasawa, S., Ueda, S., Kannagi, M., Iwakura, Y., Fujii, M., and Yonehara, S. (1997)
Resistance to Fas-mediated apoptosis of peripheral T-cells in HTLV-1 transgenic mice with autoimmune arthropathy.
J Exp Med 186, 57-64.

Senju, S., Negishi, I., Motoyama, N., Wang, F., Nakayama, K-I., Nakayama, K., Lucas, P.J., Hatakeyama, S., Zhang, Q., Yonehara, S., and Loh, D.Y. (1996)
Funcrtional significance of the Fas molecule in naive lymphocytes.
Int Immunol 8, 423-431.

Nishimura, Y., Ishii, A., Kobayashi, Y., Yamasaki, Y., and Yonehara, S. (1995)
Expression and function of mouse Fas antigen on immature and mature T cells.
J Immunol 154, 4395-4403.

Nishimura, Y., Ishii, A., and Yonehara, S. (1995)
Expression and function of apoptosis antigen Fas on T lymphocytes in periphery and thymus.
In Leucocyte Typing V: White Cell Differentiation Antigens, S.F. Schlossman, L. Boumsell, W. Gilks et al., ed. (Oxford, England: Oxford University Press), pp1144-1148.

Kneitz, B., Herrmann, T., Yonehara, S., and Schmpl, A. (1995)
Normal clonal expansion but impaired Fas-mediated cell death and anergy induction in interleukin-2-deficient mice.
Eur J Immunol 25, 2572-2577.

Owen-Schaub, L.B., Radinsky, R., Kruzel, E, Berry, K., and Yonehara, S. (1994)
Anti-Fas on nonhematopoietic tumors: Levels of Fas/APO-1 and bcl-2 are not predicted of biologic responsiveness.
Cancer Res 54, 1580-1586.

Hanabuchi, S., Koyanagi, M., Kawasaki, A., Shinohara, N., Matsuzawa, A., Nishimura, Y., Kobayashi, Y., Yonehara, S., Yagita, H., and Okumura, K. (1994)
Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity.
Proc Natl Acad Sci USA 91, 4930-4934.

Kojima, H., Shinohara, N., Hanaoka, S., Someya-Shirota, Y., Takagaki, Y., Ohno, H., Saito, T., Katayama, T., Yagita, H., Okumura, K., Shinkai, Y., Alt, F.W., Matsuzawa, A., Yonehara, S., and Takayama, H. (1994)
Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes.
Immunity 1, 357-364.

Arase, H., Arase, N., Kobayashi, Y., Nishimura, Y., Yonehara, S., and Onoe, K. (1994)
Cytotoxicity of fresh NK1.1+ T cell receptor / thymocytes against a CD4+8+ thymocyte population associated with intact Fas antigen expression on the target.
J Exp Med 180, 423-432.

Sayama, K., Yonehara, S., Watanabe, Y., and Miki, Y. (1994)
Expression of Fas antigen on keratinocytes in vivo and induction of apoptosis in cultured keratinocytes.
J Invest Dematol 103, 330-334.

Sakamaki, K., and Yonehara, S. (1994)
Serum alleviates the requirement of the granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced Ras activation for proliferation of BaF3 cells.
FEBS Letter 353, 133-137.

Yonehara, S., Nishimura, Y., Kishi, S., Yonehara, M., Takazawa, K., Tamatani, T., and Ishii, A. (1994)
Involvement of apoptosis antigen Fas in clonal deletion of human thymocytes induced by a superantigen.
Int Immunol 11, 1849-1856.