{"id":1857,"date":"2016-01-18T21:07:12","date_gmt":"2016-01-18T12:07:12","guid":{"rendered":"http:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/?page_id=1857"},"modified":"2016-05-07T17:55:26","modified_gmt":"2016-05-07T08:55:26","slug":"1857-2","status":"publish","type":"page","link":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/1857-2\/","title":{"rendered":"2011"},"content":{"rendered":"

2011 (\u8ad6\u6587)<\/h2>\n
    \n
  1. Sano K, Temma T, Azuma T, Nakai R, Narazaki M, Kuge Y, Saji H.
    \nA pre-targeting strategy for MR imaging of functional molecules using dendritic Gd-based contrast agents
    \nMol. Imaging Biol.<\/em>\u00a013<\/strong>(6) 1196-1203 (2011)<\/li>\n
  2. Arimitsu K, Kajimoto T, Kimura H, Ono M, Ozeki M, Node M, Ohmomo Y, Saji H, Yamashita M.
    \nAlternative synthesis of radioiodinated trisaccharide derivatives, 2-(4-\u00a0125<\/sup>iodophenyl)ethyl 2-acetamido-2-deoxy-\u03b2-d-glucopyranosyl- (1\u21922)-\u03b1-d-mannopyranosyl-( 1\u21926)-\u03b2-d-glucopyranoside, and preparation of its analogs having different lengths of alkyl chains instead of ethyl group: Acceptor substrates of n-acetylglucosaminyltransferase v for in vivo imaging
    \nHeterocycles<\/em>\u00a083<\/strong>(12) 2779-2802 (2011)<\/li>\n
  3. Harada N, Kimura H, Ono M, Mori D, Ohmomo Y, Kajimoto T, Kawashima H, Saji H.
    \nEffective synthesis of\u00a099m<\/sup>Tc tricarbonyl complexes by microwave heating
    \nJ. Organomet. Chem.<\/em>\u00a0696<\/strong>(23) 3745-3749 (2011)<\/li>\n
  4. Watanabe H, Ono M, Kimura H, Kagawa S, Nishii R, Fuchigami T, Haratake M, Nakayama M, Saji H.
    \nA dual fluorinated and iodinated radiotracer for PET and SPECT imaging of \u03b2-amyloid plaques in the brain
    \nBioorg. Med. Chem. Lett.<\/em>\u00a021<\/strong>(21) 6519-6522 (2011)<\/li>\n
  5. Ueda M, Kudo T, Mutou Y, Umeda I.O, Miyano A, Ogawa K, Ono M, Fujii H, Kizaka-Kondoh S, Hiraoka M, Saji H.
    \nEvaluation of [125<\/sup>I]IPOS as a molecular imaging probe for hypoxia-inducible factor-1-active regions in a tumor: Comparison among single-photon emission computed tomography\/X-ray computed tomography imaging, autoradiography, and immunohistochemistry
    \nCancer Sci.<\/em>\u00a0102<\/strong>(11) 2090-2096 (2011)<\/li>\n
  6. Shimizu Y, Temma T, Sano K, Ono M, Saji H.
    \nDevelopment of membrane type-1 matrix metalloproteinase-specific activatable fluorescent probe for malignant tumor detection
    \nCancer Sci.<\/em>\u00a0102<\/strong>(10) 1897-1903 (2011)<\/li>\n
  7. Makino A, Harada H, Okada T, Kimura H, Amano H, Saji H, Hiraoka M, Kimura S.
    \nEffective encapsulation of a new cationic gadolinium chelate into apoferritin and its evaluation as an MRI contrast agent
    \nNanomedicine: NBM<\/em>\u00a07<\/strong>(5) 638-646 (2011)<\/li>\n
  8. Kudo T, Ueda M, Konishi H, Kawashima H, Kuge Y, Mukai T, Miyano A, Tanaka S, Kizaka-Kondoh S, Hiraoka M, Saji H.
    \nPET imaging of hypoxia-inducible factor-1-active tumor cells with pretargeted oxygen-dependent degradable streptavidin and a novel\u00a018<\/sup>F-labeled biotin derivative
    \nMol. Imaging Biol.<\/em>\u00a013<\/strong>(5) 1003-1010 (2011)<\/li>\n
  9. Hagimori M, Mizuyama N, Yokota K, Morinaga O, Yamaguchi Y, Saji H, Tominaga Y.
    \nSynthesis of fluorescent pyrrolo[3,4-b]quinolizine derivatives and evaluation as a protein-labeling probe
    \nHeterocycles<\/em>\u00a083<\/strong>(9) 1983-1988 (2011)<\/li>\n
  10. Mukai T, Hagimori M, Arimitsu K, Katoh T, Ukon M, Kajimoto T, Kimura H, Magata Y, Miyoshi E, Taniguchi N, Node M, Saji H.
    \nSynthesis and evaluation of a radioiodinated trisaccharide derivative as a synthetic substrate for a sensitive N-acetylglucosaminyltransferase v radioassay
    \nBioorg. Med. Chem.<\/em>\u00a019<\/strong>(14) 4312-4321 (2011)<\/li>\n
  11. Cui M, Ono M, Kimura H, Liu B, Saji H.
    \nNovel quinoxaline derivatives for in vivo imaging of \u03b2-amyloid plaques in the brain
    \nBioorg. Med. Chem. Lett.<\/em>\u00a021<\/strong>(14) 4193-4196 (2011)<\/li>\n
  12. Cui M, Ono M, Kimura H, Liu B, Saji H.
    \nSynthesis and evaluation of benzofuran-2-yl(phenyl)methanone derivatives as ligands for \u03b2-amyloid plaques
    \nBioorg. Med. Chem.<\/em>\u00a019<\/strong>(13) 4148-4153 (2011)<\/li>\n
  13. Matsumura K, Ono M, Hayashi S, Kimura H, Okamoto Y, Ihara M, Takahashi R, Mori H, Saji H.
    \nPhenyldiazenyl benzothiazole derivatives as probes for in vivo imaging of neurofibrillary tangles in Alzheimer\u2019s disease brains
    \nMed. Chem. Commun.<\/em>\u00a02<\/strong>(7) 596-600 (2011)<\/li>\n
  14. Hirata K, Kuge Y, Yokota C, Harada A, Kokame K, Inoue H, Kawashima H, Hanzawa H, Shono Y, Saji H, Minematsu K, Tamaki N.
    \nGene and protein analysis of brain derived neurotrophic factor expression in relation to neurological recovery induced by an enriched environment in a rat stroke model
    \nNeurosci. Lett.<\/em>\u00a0495<\/strong>(3) 210-215 (2011)<\/li>\n
  15. Ono M, Hayashi S, Matsumura K,\u00a0Kimura H, Okamoto Y, Ihara M, Takahashi R, Mori H, Saji H.
    \nRhodanine and thiohydantoin derivatives for detecting tau pathology in Alzheimer\u2019s brains
    \nACS Chem. Neurosci.<\/em>\u00a02<\/strong>(5) 269-275 (2011)<\/li>\n
  16. Masuda R, Oishi S, Ohno H, Kimura H, Saji H, Fujii N.
    \nConcise site-specific synthesis of DTPA-peptide conjugates: Application to imaging probes for the chemokine receptor CXCR4
    \nBioorg. Med. Chem.<\/em>\u00a019<\/strong>(10) 3216-3220 (2011)<\/li>\n
  17. Ono M, Saji H.
    \nSPECT Imaging Agents for Detecting Cerebral beta-Amyloid Plaques.
    \nInt. J. Mol. Imaging<\/em>\u00a02011\u00a0<\/strong>543267 (2011)\u00a0Review.<\/em><\/li>\n
  18. Ono M, Cheng Y, Kimura H, Cui M, Kagawa S, Nishii R, Saji H.
    \nNovel\u00a018<\/sup>F-labeled benzofuran derivatives with improved properties for positron emission tomography (PET) imaging of \u03b2-amyloid plaques in Alzheimer\u2019s brains
    \nJ. Med. Chem.<\/em>\u00a054<\/strong>(8) 2971-2979 (2011)<\/li>\n
  19. Cui M, Ono M, Kimura H, Liu B, Saji H.
    \nSynthesis and structure-affinity relationships of novel dibenzylideneacetone derivatives as probes for \u00df-Amyloid Plaques
    \nJ. Med. Chem.<\/em>\u00a054<\/strong>(7) 2225-2240 (2011)<\/li>\n
  20. Cui M, Ono M, Kimura H, Kawashima H, Liu B.L, Saji H.
    \nRadioiodinated benzimidazole derivatives as single photon emission computed tomography probes for imaging of \u03b2-amyloid plaques in Alzheimer\u2019s disease
    \nNucl. Med. Biol.<\/em>\u00a038<\/strong>(3) 313-320 (2011)<\/li>\n
  21. Shimizu S, Atsumi R, Nakazawa T, Izumi T, Sudo K, Okazaki O, Saji H.
    \nTiclopidine-induced hepatotoxicity in a GSH-depleted rat model
    \nArch. Toxicol.<\/em>\u00a085<\/strong>(4) 347-353 (2011)<\/li>\n
  22. Shono Y, Yokota C, Kuge Y, Kido S, Harada A, Kokame K, Inoue H, Hotta M, Hirata K, Saji H, Tamaki N, Minematsu K.
    \nGene expression associated with an enriched environment after transient focal ischemia
    \nBrain Res.<\/em>\u00a01376<\/strong>\u00a060-65 (2011)<\/li>\n
  23. Hagimori M, Mizuyama N, Yamaguchi Y, Saji H, Tominaga Y.
    \nA novel small molecule fluorescent sensor for Zn2+<\/sup>\u00a0based on pyridine-pyridone scaffold
    \nTalanta<\/em>,\u00a083<\/strong>(5) 1730-1735 (2011)<\/li>\n
  24. Cui M, Ono M, Kimura H, Liu B.L., Saji H.
    \nSynthesis and biological evaluation of indole-chalcone derivatives as \u03b2-amyloid imaging probe
    \nBioorg. Med. Chem. Lett.<\/em>\u00a021<\/strong>(3) 980-982 (2011)<\/li>\n
  25. Ueda M, Iida Y, Yoneyama T, Kawai T, Ogawa M, Magata Y, Saji H.
    \nIn vivo relationship between thalamic nicotinic acetylcholine receptor occupancy rates and antiallodynic effects in a rat model of neuropathic pain: Persistent agonist binding inhibits the expression of antiallodynic effects
    \nSynapse<\/em>,\u00a065<\/strong>(1) 77-83 (2011)<\/li>\n
  26. Ono M, Watanabe H, Watanabe R, Haratake M, Nakayama M, Saji H.
    \nDiphenylpropynone derivatives as probes for imaging \u03b2-amyloid plaques in Alzheimer\u2019s brains
    \nBioorg. Med. Chem. Lett.<\/em>\u00a021<\/strong>(1) 117-120 (2011)<\/li>\n<\/ol>\n

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