{"id":363,"date":"2013-07-12T15:06:09","date_gmt":"2013-07-12T06:06:09","guid":{"rendered":"http:\/\/www.keyton-co.jp\/kpharm\/byotai\/?page_id=363"},"modified":"2026-04-12T11:30:01","modified_gmt":"2026-04-12T02:30:01","slug":"researc","status":"publish","type":"page","link":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/researc\/","title":{"rendered":"\u7814\u7a76\u696d\u7e3e"},"content":{"rendered":"<h2>2026 (\u8ad6\u6587)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Akiba H, Nakashima K, Ichinose T, Watanabe H, Ono M<br \/>\n<span class=\"Apple-style-span\">Influence of the binding valency of anti-HER2 biparatopic antibodies on biodistribution in an SK-OV-3 tumor xenograft model<br \/>\n<\/span><span lang=\"EN-US\"><em>Mol<\/em><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><em>. Pharm<span class=\"Apple-style-span\">.<\/span><\/em><span class=\"Apple-style-span\"> in press<\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: 10.1021\/acs.molpharmaceut.5c01515<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Hasegawa T, Nakashima K, Watanabe H, Ono M<br \/>\n<span class=\"Apple-style-span\">Dual pharmacokinetic modifier strategy for synergistically enhanced tumor accumulation of PSMA-targeting radioligand<br \/>\n<\/span><span lang=\"EN-US\"><em>Chem<\/em><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><em>. Commun<span class=\"Apple-style-span\">.<\/span><\/em><span class=\"Apple-style-span\"> 62 4851-4854 (2026)<\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: 10.1039\/d5cc06620d<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Nakashima K, Ono M<br \/>\n<span class=\"Apple-style-span\">Reply to the letter to the editor from Drs. Huang and Chen<br \/>\n<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span class=\"Apple-style-span\"><em>Ann. Nucl. Med. <\/em>in press<br \/>\nDOI: 10.1007\/s12149-026-02167-3<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Saito K, Watanabe H, Nakashima K, Chiba Y, Hashimoto K, Fujino S, Kawauchi Y, Saeki H, Takashima N, Kawabata M, Ono M<br \/>\n<span class=\"Apple-style-span\">Preclinical evaluation of novel <sup>177<\/sup>Lu-labeled fibroblast activation protein inhibitor with albumin binder for radioligand therapy<br \/>\n<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span class=\"Apple-style-span\"><em>Ann. Nucl. Med. <\/em>in press<br \/>\nDOI: 10.1007\/s12149-026-02167-3<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Okuyama C, Oishi N, Ishizu K, Hasegawa H, Ito M, Fujita Y, Kusano K, Okina T, Kagawa S, Watanabe H, Higashi T, Yamauchi H, Ono M<br \/>\n<span class=\"Apple-style-span\">A new amyloid PET evaluation method using separated gray-matter histogram based on three-component model<br \/>\n<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span class=\"Apple-style-span\"><em>Ann. Nucl. Med. <\/em>in press<br \/>\nDOI: 10.1007\/s12149-026-02157-5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Yamane T, Kazuta N, Nakashima K, Watanabe H, Ono M<br \/>\n<span class=\"Apple-style-span\">Effect of Structural Alteration in Albumin Binder Moiety on Tumor Accumulation of Somatostatin Receptor 2\u2011Targeted Radioligands<br \/>\n<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span class=\"Apple-style-span\"><em>ACS Pharmacol. Transl. Sci. <\/em>9(2) 348-358 (2026)<br \/>\nDOI: 10.1021\/acsptsci.5c00591<\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/p>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<\/li>\n<\/ol>\n<h2>2026 (\u5b66\u4f1a\u767a\u8868\u306a\u3069)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u8d64\u5742 \u8cb4\u6d69, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u51dd\u96c6\u4f53\u306e\u6838\u533b\u5b66\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u304a\u3088\u3073\u5149\u9178\u7d20\u5316\u3092\u76ee\u7684\u3068\u3057\u305f<sup>18<\/sup>F\u6a19\u8b58\u30d0\u30a4\u30c1\u30aa\u30d5\u30a7\u30f3\u8a98\u5c0e\u4f53\u306e\u5408\u6210\u3068\u8a55\u4fa1<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c146\u5e74\u4f1a (\u5927\u962a) 2026\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u751a\u7530 \u6d38\u5e0c, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u524d\u7acb\u817a\u7279\u7570\u7684\u819c\u6297\u539f\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u898f\u30dd\u30ea\u30a8\u30c1\u30ec\u30f3\u30b0\u30ea\u30b3\u30fc\u30eb\u542b\u6709\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c146\u5e74\u4f1a (\u5927\u962a) 2026\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c71\u672c \u8cb4\u88d5, \u4e2d\u5cf6 \u4e00\u78e8, \u6570\u591a \u4f38\u7d00, \u6a4b\u672c \u548c\u5e78, \u5343\u8449 \u60a0\u4ecb, \u85e4\u91ce \u96bc\u8f14, \u6cb3\u5185 \u5e78\u6b63, \u4f50\u4f2f \u79c0\u4e5f, \u9ad8\u5cf6 \u76f4\u8cb4, \u5ddd\u7aef \u65b9\u5b50, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u30b3\u30ec\u30b7\u30b9\u30c8\u30ad\u30cb\u30f32\u53d7\u5bb9\u4f53\u6a19\u7684\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u306b\u8cc7\u3059\u308b\u65b0\u898f<sup>111<\/sup>In\/<sup>177<\/sup>Lu\u6a19\u8b58\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c146\u5e74\u4f1a (\u5927\u962a) 2026\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u571f\u6a4b \u660c\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u524d\u7acb\u817a\u304c\u3093\u3092\u6a19\u7684\u3068\u3057\u305f\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u542b\u6709\u65b0\u898f\u30d8\u30c6\u30ed\u30c0\u30a4\u30de\u30fc\u578b\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c146\u5e74\u4f1a (\u5927\u962a) 2026\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u67cf\u5c71 \u9678\u6597, \u6e21\u908a \u88d5\u4e4b, \u8d64\u5742 \u8cb4\u6d69, \u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u30aa\u30fc\u30b8\u30a7\u96fb\u5b50\u304c\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u51dd\u96c6\u904e\u7a0b\u306b\u53ca\u307c\u3059\u4f5c\u7528\u306e\u8a55\u4fa1<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c146\u5e74\u4f1a (\u5927\u962a) 2026\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c71\u6839 \u62d3\u771f, \u4e2d\u5cf6 \u4e00\u78e8, \u6570\u591a \u4f38\u7d00, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u795e\u7d4c\u5185\u5206\u6ccc\u816b\u760d\u306e\u8a3a\u65ad\u30fb\u6cbb\u7642\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898f\u4e8c\u4fa1\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u542b\u6709\u653e\u5c04\u6027\u30ea\u30ac\u30f3\u30c9\u306e\u958b\u767a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c146\u5e74\u4f1a (\u5927\u962a) 2026\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5927\u6d25 \u660c\u7fa9, \u9f4b\u85e4 \u6d69\u8f14, \u4e2d\u5cf6 \u4e00\u78e8, \u85e4\u672c \u88d5\u4e4b, \u6751\u4e0a \u660c\u53f2, \u5927\u6c5f \u4e00\u5f18, \u8c4a\u5d8b \u539a\u53f2, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u6a19\u7684\u03b1\u7dda\u6cbb\u7642\u306e\u305f\u3081\u306e\u65b0\u898f\u30cb\u30e5\u30fc\u30ed\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f531\u6a19\u7684<sup>211<\/sup>At\u6a19\u8b58\u85ac\u5264\u306e\u958b\u767a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c146\u5e74\u4f1a (\u5927\u962a) 2026\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">, \u6e21\u908a \u88d5\u4e4b, <\/span><\/span>\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u304c\u3093\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u3092\u6307\u5411\u3057\u305fantibody-radionuclide conjugate\u306e\u5206\u5b50\u8a2d\u8a08\u6226\u7565<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c146\u5e74\u4f1a (\u5927\u962a) 2026\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">Research on Radiopharmaceutical Chemistry for Theranostics<br \/>\n<span style=\"font-size: 14px;text-indent: 1em\">Substantia Life Science \u7814\u7a76\u4ea4\u6d41\u4f1a\uff08\u4eac\u90fd\uff092026\u5e743\u67083\u65e5<\/span><\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2025 (\u8ad6\u6587)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Nakashima K, Yamaguchi K, Saito K, Watanabe H, Ono M.<br \/>\n<span class=\"Apple-style-span\">Novel bivalent albumin binder for enhanced tumor retention of fibroblast activation protein-targeted radioligand<br \/>\n<\/span><span lang=\"EN-US\"><em>Chem<\/em><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><em>. Commun<span class=\"Apple-style-span\">.<\/span><\/em><span class=\"Apple-style-span\"> 61(96) 19072-19075 (2025)<\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: <\/span><\/span><\/span><span style=\"font-size: 14px;color: #333333;text-indent: 1em\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">10.1039\/d5cc05231a<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Watanabe H, Saito H, Nakashima K, Ono M.<br \/>\n<span class=\"Apple-style-span\">Structure-Activity Relationships of Azaquinazolinone Derivatives as <sup>18<\/sup>F-Labeled PET Probes Targeting Ghrelin Receptors<br \/>\n<\/span><span lang=\"EN-US\"><em>J. Med. Chem<span class=\"Apple-style-span\">.<\/span><\/em><span class=\"Apple-style-span\"> 68(21) 22288-22300 (2025)<\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: <\/span><\/span><\/span><span style=\"font-size: 14px;color: #333333;text-indent: 1em\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">10.1021\/acs.jmedchem.5c01070<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Akasaka T, Watanabe H, Ono M.<br \/>\n<span class=\"Apple-style-span\">Novel BODIPY-Based Fluorescent Probes with Improved Aqueous Solubility for Selective Detection of Soluble A\u03b2 Aggregates<\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>ACS Chem. Neurosci.<\/em> 16(21) 4257-4266 (2025)<em><br \/>\n<\/em>DOI: 10.1021\/acschemneuro.5c00525<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Nakashima K, Jinda H, Shimohara H, Watanabe H, Ono M.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">Control of pharmacokinetics of radioimmunoconjugates using chelating agents containing poly(ethylene glycol)<br \/>\n<\/span><\/span><span lang=\"EN-US\"><em>J. Control. Release <\/em>388, 114293 <span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">(2025)<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.jconrel.2025.114293<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Saito K, Watanabe H, Yamaguchi K, Nakashima K, Ono M.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">Impact of Albumin-Binding Moieties on Structure-Affinity-Pharmacokinetic Relationships of Novel FAP-Targeting Radioligands<br \/>\n<\/span><\/span><span lang=\"EN-US\"><em>Mol. Pharm.<\/em> 22<span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">(10) 5989-5998 (2025)<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.molpharmaceut.5c00631<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Kashiyama R, Watanabe H, Akasaka T, Fujimoto H, Murakami M, Ooe K, Toyoshima A, Nakashima K, Ono M.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">Feasibility of targeted alpha therapy for Alzheimer\u2019s disease using <sup>211<\/sup>At\u2010labeled agent targeting amyloid\u2010\u03b2 aggregates<br \/>\n<\/span><\/span><span lang=\"EN-US\"><span class=\"Apple-style-span\"><em>Ann. Nucl. Med. <\/em>39<span style=\"font-size: 14px;text-indent: 1em\">(12) 1319-1325 (2025)<\/span><\/span> <\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: 10.1007\/s12149-025-02095-8<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Kazuta N, Nakashima K, Watanabe H, Ono M<br \/>\n<span class=\"Apple-style-span\">Development of Novel Integrin \u03b1v\u03b23-targeted Radioligand for Enhanced Tumor Accumulation<br \/>\n<\/span><span lang=\"EN-US\"><em>ACS Med. Chem. Lett.<\/em> 16<span class=\"Apple-style-span\">(7) 1346-1353 (2025)<\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: 10.1021\/acsmedchemlett.5c00231<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Hasegawa T, Nakashima K, Tarumizu Y, Tada M, Maya Y, Watanabe H, Ono M.<br \/>\n<span class=\"Apple-style-span\">Development of Novel Radiotheranostic Ligand with Positively Charged Unit Targeting Prostate-Specific Membrane Antigen<br \/>\n<\/span><span lang=\"EN-US\"><em>J. Med. Chem<\/em><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><em>. <\/em>68<span class=\"Apple-style-span\">(10) 10190-10202 (2025)<\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: <\/span><\/span><\/span><span style=\"font-size: 14px;color: #333333;text-indent: 1em\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">10.1021\/acs.jmedchem.5c00370<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Tsuchihashi S, Nakashima K, Watanabe H, Ono M.<br \/>\n<span class=\"Apple-style-span\">Development of Novel Gastrin-Releasing Peptide Receptor-targeted Radioligand with Albumin Binder to Improve Accumulation in Tumor<br \/>\n<\/span><span lang=\"EN-US\"><em>ACS Med. Chem. Lett. <\/em>16<span class=\"Apple-style-span\">(5) 797-803 (2025)<\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI:\u00a0<\/span><\/span><\/span><span style=\"font-size: 14px;color: #333333;text-indent: 1em\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">10.1021\/acsmedchemlett.5c00032<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Nakashima K, Ichinose T, Watanabe H, Ono M.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span style=\"font-size: 14px;text-indent: 1em\">Comparison of Carbonic Anhydrase-IX-targeted Trifunctional Radioligands between Linear- and Branched-chain Arrangements<br \/>\n<\/span><span lang=\"EN-US\"><em>Front. Nucl. Med.<\/em> 5<span class=\"Apple-style-span\"> 1583027 (2025)<\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: 10.3389\/fnume.2025.1585027<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Saito K, Watanabe H, Nakashima K, Ono M.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">Preclinical Characterization of Novel FAP-2286-Based Radioligand with Albumin Binder for Improved Tumor Retention<br \/>\n<\/span><\/span><span lang=\"EN-US\"><em>ACS Med. Chem. Lett.<\/em> 16<span class=\"Apple-style-span\">(4) 596-601 (2025)<\/span><\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: 10.1021\/acsmedchemlett.4c00630<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Kashiyama R, Watanabe H, Akasaka T, Ono M.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">Novel amyloid-\u03b2 oligomer-targeted fluorescent probes by introducing branched chain into push-pull type dye<br \/>\n<\/span><\/span><span lang=\"EN-US\"><em>Dyes Pigm. <\/em>236 112680 (2025)\u00a0<\/span><\/span><span style=\"color: #333333\"><span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em;color: #333333\"><span style=\"color: #333333\"><span lang=\"EN-US\">DOI: <\/span><\/span>10.1016\/j.dyepig.2025.112680<\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Okuyama C, Inuzuka Y, Takeuchi Y, Asagoe K, Kagawa S, Ito M, Kusano K, Fujita Y, Watanabe H, Ono M, Higashi T.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">Imaging of cardiac amyloidosis using dynamic <sup>18<\/sup>F-FPYBF-2 positron emission tomography<\/span><\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Ann. Nucl. Med. <\/em>39(4) 398-403 (2025)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1007\/s12149-024-02010-7<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Nakashima K, Shimohara H, Watanabe H, Ono M.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">Improvement of tumor-to-blood ratio of radioimmunoconjugates by poly(ethyleneimine)-containing chelating agent<br \/>\n<\/span><\/span><span lang=\"EN-US\"><em>Ann. Nucl. Med.<\/em> 39(4) 323-333 (2025)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1007\/s12149-024-02003-6<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">Kazuta N, Nakashima K, Tarumizu Y, Sato T, Maya Y, Watanabe H, Ono M.<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">Novel Radiotheranostic Ligands Targeting Prostate-Specific Membrane Antigen Based on Dual Linker Approach<br \/>\n<\/span><\/span><span lang=\"EN-US\"><em>Mol. Pharm. <\/em>22(1) 377-386 (2025)<em>\u00a0<\/em><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.molpharmaceut.4c00974<\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2025 (\u5b66\u4f1a\u767a\u8868\u306a\u3069)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u9f4b\u85e4 \u6d69\u8f14, \u6e21\u908a \u88d5\u4e4b, \u4e2d\u5cf6 \u4e00\u78e8, \u5343\u8449 \u60a0\u4ecb, \u6a4b\u672c \u548c\u5e78, \u85e4\u91ce \u96bc\u8f14, \u6cb3\u5185 \u5e78\u6b63, \u4f50\u4f2f \u79c0\u4e5f, \u9ad8\u5cf6 \u76f4\u8cb4, \u5ddd\u7aef \u65b9\u5b50, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">FAP\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u898f<sup>111<\/sup>In\/<sup>177<\/sup>Lu\u6a19\u8b58\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u85ac\u5264\u306e\u958b\u767a<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c3\u56de\u77ed\u5bff\u547dRI\u5229\u7528\u7814\u7a76\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff08\u5bae\u57ce\uff092025\u5e7411\u670828\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u67cf\u5c71 \u9678\u6597, \u6e21\u908a \u88d5\u4e4b, \u8d64\u5742 \u8cb4\u6d69, \u85e4\u672c \u88d5\u4e4b, \u6751\u4e0a \u660c\u53f2, \u5927\u6c5f \u4e00\u5f18, \u8c4a\u5d8b \u539a\u53f2, \u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><sup>211<\/sup>At<\/span><\/span><\/span><\/span><\/span>\u6a19\u8b58\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u30d7\u30ed\u30fc\u30d6\u306e\u5408\u6210\u3068\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u6cbb\u7642\u7528\u85ac\u5264\u3068\u3057\u3066\u306e\u57fa\u790e\u7684\u8a55\u4fa1<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c3\u56de\u77ed\u5bff\u547dRI\u5229\u7528\u7814\u7a76\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff08\u5bae\u57ce\uff092025\u5e7411\u670828\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u8133\u5185\u30aa\u30ec\u30ad\u30b7\u30f3\u53d7\u5bb9\u4f53\u3092\u6a19\u7684\u3068\u3057\u305fPET\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a\u7814\u7a76<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c3\u56de\u77ed\u5bff\u547dRI\u5229\u7528\u7814\u7a76\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff08\u5bae\u57ce\uff092025\u5e7411\u670828\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u9f4b\u85e4 \u6d69\u8f14, \u6e21\u908a \u88d5\u4e4b, \u4e2d\u5cf6 \u4e00\u78e8, \u5343\u8449 \u60a0\u4ecb, \u6a4b\u672c \u548c\u5e78, \u85e4\u91ce \u96bc\u8f14, \u6cb3\u5185 \u5e78\u6b63, \u4f50\u4f2f \u79c0\u4e5f, \u9ad8\u5cf6 \u76f4\u8cb4, \u5ddd\u7aef \u65b9\u5b50, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u7dda\u7dad\u82bd\u7d30\u80de\u6d3b\u6027\u5316\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6a19\u7684\u3068\u3057\u305f<sup>177<\/sup>Lu\u6a19\u8b58\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u7d50\u5408\u578b\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u571f\u6a4b \u660c\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u524d\u7acb\u817a\u304c\u3093\u306b\u304a\u3051\u308bPSMA\u304a\u3088\u3073GRPR\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u898f\u653e\u5c04\u6a19\u8b58\u30d8\u30c6\u30ed\u30c0\u30a4\u30de\u30fc\u306e\u958b\u767a<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6570\u591a \u4f38\u7d00, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u65b0\u898f\u30ea\u30f3\u30ab\u30fc\u6280\u8853\u3092\u7528\u3044\u305f\u30a4\u30f3\u30c6\u30b0\u30ea\u30f3\u03b1v\u03b23\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u816b\u760d\u96c6\u7a4d\u6027\u306b\u95a2\u3059\u308b\u691c\u8a0e<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c71\u672c \u8cb4\u88d5, \u4e2d\u5cf6 \u4e00\u78e8, \u6570\u591a \u4f38\u7d00, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u30b3\u30ec\u30b7\u30b9\u30c8\u30ad\u30cb\u30f32\u53d7\u5bb9\u4f53\u3092\u6a19\u7684\u3068\u3057\u305f\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u542b\u6709\u653e\u5c04\u6027\u30ea\u30ac\u30f3\u30c9\u306e\u958b\u767a<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c71\u6839 \u62d3\u771f, \u6570\u591a \u4f38\u7d00, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u30a2\u30eb\u30d6\u30df\u30f3\u7d50\u5408\u6027\u306b\u7740\u76ee\u3057\u305f\u65b0\u898fSSTR2\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u9577\u8c37\u5ddd \u62d3\u771f, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">2\u7a2e\u306e\u4f53\u5185\u52d5\u614b\u5236\u5fa1\u30e6\u30cb\u30c3\u30c8\u3092\u7528\u3044\u305f\u65b0\u898fPSMA\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u67cf\u5c71 \u9678\u6597, \u6e21\u908a \u88d5\u4e4b, \u8d64\u5742 \u8cb4\u6d69, \u85e4\u672c \u88d5\u4e4b, \u6751\u4e0a \u660c\u53f2, \u5927\u6c5f \u4e00\u5f18, \u8c4a\u5d8b \u539a\u53f2, \u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">\u30a2\u30eb\u30c4\u30cf\u30a4\u30de\u30fc\u75c5\u306e\u6a19\u7684\u03b1\u7dda\u6cbb\u7642\u7528\u85ac\u5264\u958b\u767a\u306b\u95a2\u3059\u308b\u57fa\u790e\u7684\u7814\u7a76<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">Development of Novel Trifunctional Chelating Agents That Enhance Tumor Retention of Radioimmunoconjugates<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\">Development of bimodal agents for auger electron and photodynamic combination therapy<br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c65\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff092025\u5e7411\u670813\u65e5\u301c15\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30a2\u30eb\u30d6\u30df\u30f3\u3068\u306e\u76f8\u4e92\u4f5c\u7528\u3092\u6d3b\u7528\u3057\u305f\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u85ac\u5264\u306e\u958b\u767a\u6226\u7565<span style=\"font-size: 14px;text-indent: 1em\">(\u7279\u5225\u8b1b\u6f14)<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c32\u56de \u65e5\u672c\u8840\u6db2\u4ee3\u66ff\u7269\u5b66\u4f1a\u5e74\u6b21\u5927\u4f1a (\u718a\u672c) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2025\u5e7410\u670830\u65e5, 31\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u8fbb \u7965\u592a\u90ce, \u5c0f\u91ce \u6b63\u535a, \u4e0a\u5e73 \u6b63\u9053, \u6797 \u660e\u5e0c\u7537<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">SKM9-2\u3092\u7528\u3044\u305f\u4e2d\u76ae\u816b\u306b\u5bfe\u3059\u308bRI\u6a19\u8b58\u6297\u4f53\u533b\u85ac\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c6\u56de \u65e5\u672c\u77f3\u7dbf\u30fb\u4e2d\u76ae\u816b\u5b66\u4f1a\u5b66\u8853\u96c6\u4f1a (\u5175\u5eab) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2025\u5e7410\u67084\u65e5, 5\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u5c71\u6839 \u62d3\u771f, \u6570\u591a \u4f38\u7d00, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30bd\u30de\u30c8\u30b9\u30bf\u30c1\u30f3\u53d7\u5bb9\u4f532\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u898f\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u542b\u6709\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c75\u56de \u65e5\u672c\u85ac\u5b66\u4f1a\u95a2\u897f\u652f\u90e8\u7dcf\u4f1a\u30fb\u5927\u4f1a (\u4eac\u90fd) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2025\u5e7410\u67084\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u5927\u6d25 \u660c\u7fa9, \u9f4b\u85e4 \u6d69\u8f14, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30cb\u30e5\u30fc\u30ed\u30c6\u30f3\u30b7\u30f3\u53d7\u5bb9\u4f531\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u898f\u653e\u5c04\u6027\u30e8\u30a6\u7d20\u6a19\u8b58\u85ac\u5264\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c75\u56de \u65e5\u672c\u85ac\u5b66\u4f1a\u95a2\u897f\u652f\u90e8\u7dcf\u4f1a\u30fb\u5927\u4f1a (\u4eac\u90fd) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2025\u5e7410\u67084\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u2ed1\u8c37\u5ddd \u62d3\u771f, \u4e2d\u5cf6 \u4e00\u78e8, \u5782\u6c34 \u52c7\u592a, \u591a\u7530 \u5321\u5229, \u771e\u77e2 \u5553\u53f2, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a\u00a0<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u6b63\u96fb\u8377\u30e6\u30cb\u30c3\u30c8\u3092\u6709\u3059\u308b\u65b0\u898fPSMA\u6a19\u7684\u30e9\u30b8\u30aa\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c8\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5206\u79d1\u4f1a \u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u7814\u7a76\u4f1a\/<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c24<\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u56de\u653e\u5c04\u6027\u533b\u85ac\u54c1\u30fb\u753b\u50cf\u8a3a\u65ad\u85ac\u7814\u7a76\u4f1a<\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u798f\u5ca1)\u00a0 <\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2025\u5e749\u67086\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u9f4b\u85e4 \u6d69\u8f14, \u6e21\u908a \u88d5\u4e4b, \u5c71\u53e3 \u6075\u8056, \u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u816b\u760d\u96c6\u7a4d\u5411\u4e0a\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898fFAP\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c8\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5206\u79d1\u4f1a \u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u7814\u7a76\u4f1a\/<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c24<\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u56de\u653e\u5c04\u6027\u533b\u85ac\u54c1\u30fb\u753b\u50cf\u8a3a\u65ad\u85ac\u7814\u7a76\u4f1a<\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u798f\u5ca1)\u00a0 <\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2025\u5e749\u67086\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u571f\u6a4b \u660c\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u9f4b\u85e4 \u6d69\u8f14, \u6a4b\u672c \u548c\u5e78, \u5343\u8449 \u60a0\u4ecb, \u85e4\u91ce \u96bc\u8f14, \u6cb3\u5185 \u5e78\u6b63, \u4f50\u4f2f \u79c0\u4e5f, \u9ad8\u5cf6 \u76f4\u8cb4, \u5ddd\u7aef \u65b9\u5b50, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u304c\u3093\u306e\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898fGRPR\u6a19\u7684<sup>111<\/sup>In\/<sup>177<\/sup>Lu\u6a19\u8b58\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c8\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5206\u79d1\u4f1a \u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u7814\u7a76\u4f1a\/<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c24<\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u56de\u653e\u5c04\u6027\u533b\u85ac\u54c1\u30fb\u753b\u50cf\u8a3a\u65ad\u85ac\u7814\u7a76\u4f1a<\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u798f\u5ca1)\u00a0 <\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2025\u5e749\u67086\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\">Nobuki Kazuta, Shohei Tsuchihashi, Hiroyuki Watanabe, Kazuma Nakashima, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">Impact of albumin-binding on tumor accumulation of PSMA-targeted radioligands<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c5\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2025\u5e749\u67083\u65e5, 4\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\">Kosuke Saito, Hiroyuki Watanabe, Keisei Yamaguchi, Kazuma Nakashima, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">Novel radioligands for fibroblast activation protein utilizing albumin binder<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c5\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2025\u5e749\u67083\u65e5, 4\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Shohei Tsuchihashi, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Development of novel radiolabeled agent targeting gastrin- releasing peptide receptor for enhanced tumor accumulation<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c5\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2025\u5e749\u67083\u65e5, 4\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u672a\u6765\u3092\u62d3\u304f\u85ac\u5b66 \u301c\u304c\u3093\u3068\u8a8d\u77e5\u75c7\u306e\u65b0\u3057\u3044\u85ac\u301c\u3000(\u6559\u54e1\u8b1b\u6f14)<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u4eac\u90fd\u5927\u5b66 mini\u30aa\u30fc\u30d7\u30f3\u30ad\u30e3\u30f3\u30d1\u30b92025 in TOKYO 2025\u5e748\u670831\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u751a\u7530 \u6d38\u5e0c, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u653e\u5c04\u6027\u85ac\u5264\u306e\u304c\u3093\u7d30\u80de\u5185\u6ede\u7559\u6027\u306e\u5411\u4e0a\u3092\u76ee\u7684\u3068\u3057\u305f\u30ab\u30c6\u30d7\u30b7\u30f3B\u7d50\u5408\u6027\u30ad\u30ec\u30fc\u30c8\u30ea\u30f3\u30ab\u30fc\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7523\u5b66\u5408\u540c\u535a\u58eb\u767a\u8868\u4ea4\u6d41\u4f1a\uff08\u4eac\u90fd\uff09<span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2025\u5e748\u670829\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u4e2d\u91ce \u5927\u6a39, \u6e21\u908a \u88d5\u4e4b, \u9f4b\u85e4 \u6d69\u8f14, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30bf\u30f3\u30d1\u30af\u8cea\u30fb\u30da\u30d7\u30c1\u30c9\u306e\u30c1\u30ed\u30b7\u30f3\u7279\u7570\u7684RI\u6a19\u8b58\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898f\u4e8c\u5b98\u80fd\u6027\u30ad\u30ec\u30fc\u30c8\u8a66\u85ac\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7523\u5b66\u5408\u540c\u535a\u58eb\u767a\u8868\u4ea4\u6d41\u4f1a\uff08\u4eac\u90fd\uff09<span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2025\u5e748\u670829\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u6dfa\u96db \u7a42\u4e43\u82b1, \u4e2d\u5cf6 \u4e00\u78e8, \u9577\u8c37\u5ddd \u62d3\u771f, \u00a0\u85e4\u672c \u88d5\u4e4b, \u6751\u4e0a \u660c\u53f2, \u5927\u6c5f \u4e00\u5f18, \u8c4a\u5d8b \u539a\u53f2, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u524d\u7acb\u817a\u7279\u7570\u7684\u819c\u6297\u539f\u3092\u6a19\u7684\u3068\u3057\u305f <sup>211<\/sup>At\u6a19\u8b58\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u542b\u6709\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c22\u56de\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u306e\u305f\u3081\u306e\u30d5\u30a3\u30b8\u30ab\u30eb\u30fb\u30d5\u30a1\u30fc\u30de\u30d5\u30a9\u30fc\u30e9\u30e0\uff08\u798f\u5ca1\uff09<span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2025\u5e748\u670821\u65e5, 22\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u7530\u4e2d \u771f\u592e, \u6570\u591a \u4f38\u7d00, \u571f\u6a4b \u660c\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u304c\u3093\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u4f53\u5185\u52d5\u614b\u5236\u5fa1\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898f\u8102\u80aa\u9178\u578b\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u306e\u63a2\u7d22<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c22\u56de\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u306e\u305f\u3081\u306e\u30d5\u30a3\u30b8\u30ab\u30eb\u30fb\u30d5\u30a1\u30fc\u30de\u30d5\u30a9\u30fc\u30e9\u30e0\uff08\u798f\u5ca1\uff09<span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2025\u5e748\u670821\u65e5, 22\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u672a\u6765\u3092\u62d3\u304f\u85ac\u5b66 \u301c\u304c\u3093\u3068\u8a8d\u77e5\u75c7\u306e\u65b0\u3057\u3044\u85ac\u301c\u3000(\u6559\u54e1\u8b1b\u6f14)<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u4eac\u90fd\u5927\u5b66 mini\u30aa\u30fc\u30d7\u30f3\u30ad\u30e3\u30f3\u30d1\u30b92025 in NAGOYA 2025\u5e748\u670818\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u85ac\u5b66\u3067\u62d3\u304f\u672a\u6765\u306e\u304c\u3093\u6cbb\u7642 \u301c\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u3078\u306e\u6311\u6226\u301c\u3000(\u6a21\u64ec\u6388\u696d)<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u4eac\u90fd\u5927\u5b66\u85ac\u5b66\u90e8\u30aa\u30fc\u30d7\u30f3\u30ad\u30e3\u30f3\u30d1\u30b9 2025\u5e748\u67087\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Shohei Tsuchihashi, Kazuma Nakashima, Hiroki Jinda, Hiroyuki Watanabe, Masahiro Ono<\/span><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">Radiotheranostics via Chemical Modulation of Pharmacokinetics<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u4eac\u5927\u9662\u85ac-\u533b\u85ac\u57fa\u76e4\u7814\u9023\u643a\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 (\u4eac\u90fd) 2025\u5e747\u670825\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u8d64\u5742 \u8cb4\u6d69, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u6c34\u6eb6\u6027BODIPY\u8a98\u5c0e\u4f53\u306eA\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u6a19\u7684\u86cd\u5149\u30d7\u30ed\u30fc\u30d6\u3068\u3057\u3066\u306e\u6709\u7528\u6027\u8a55\u4fa1<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c19\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a (\u798f\u4e95) 2025\u5e745\u670829\u65e5, 30\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b, \u9f4b\u85e4 \u6674\u9999, \u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u30a2\u30b6\u30ad\u30ca\u30be\u30ea\u30ce\u30f3\u9aa8\u683c\u3092\u57fa\u76e4\u3068\u3057\u305f\u30b0\u30ec\u30ea\u30f3\u53d7\u5bb9\u4f53\u6a19\u7684PET\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c19\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a (\u798f\u4e95) 2025\u5e745\u670829\u65e5, 30\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\">Kosuke Saito, Hiroyuki Watanabe, Kazuma Nakashima, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Development of novel fibroblast activation protein-targeting radioligand with albumin binder to improve tumor retention<\/span><br \/>\n<\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 26th International Symposium on Radiopharmaceutical Sciences (Gold Coast, Australia) May 11-15, 2025<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\">Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Novel strategy using PEGylated chelating agents to enhance tumor retention of radioimmunoconjugates\u00a0<\/span><br \/>\n<\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 26th International Symposium on Radiopharmaceutical Sciences (Gold Coast, Australia) May 11-15, 2025<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\">Rikuto Kashiyama, Hiroyuki Watanabe, Takahiro Akasaka, Hiroyuki Fujimoto, Masashi Murakami, Kazuhiro Ooe, Atsushi Toyoshima, Kazuma Nakashima, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Potential of <sup>211<\/sup>At-Labeled Amyloid-\u03b2 Binding Agent for Targeted Alpha Therapy in Alzheimer\u2019s Disease\u00a0<\/span><br \/>\n<\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 26th International Symposium on Radiopharmaceutical Sciences (Gold Coast, Australia) May 11-15, 2025<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">PET\u691c\u67fb\u85ac\u306e\u88fd\u9020\u30fb\u7ba1\u7406 (PET\u7814\u4fee\u30bb\u30df\u30ca\u30fc)<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c25\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u6625\u5b63\u5927\u4f1a (\u30aa\u30f3\u30e9\u30a4\u30f3) 2025\u5e744\u670824\u65e5\u301c6\u67083\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u9577\u8c37\u5ddd \u62d3\u771f, \u4e2d\u5cf6 \u4e00\u78e8, \u5782\u6c34 \u52c7\u592a, \u591a\u7530 \u5321\u5229, \u5c0d\u99ac \u7406\u5f66, \u771e\u77e2 \u5553\u53f2, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u6b63\u96fb\u8377\u30e6\u30cb\u30c3\u30c8\u3092\u6709\u3059\u308b<sup>111<\/sup>In\/<sup>225<\/sup>Ac\u6a19\u8b58PSMA\u6a19\u7684\u85ac\u5264\u3092\u7528\u3044\u305f\u304c\u3093\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c145\u5e74\u4f1a (\u798f\u5ca1) 2025\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u9f4b\u85e4 \u6d69\u8f14, \u6e21\u908a \u88d5\u4e4b, \u5c71\u53e3 \u6075\u8056, \u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u7dda\u7dad\u82bd\u7d30\u80de\u6d3b\u6027\u5316\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u898f\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u7d50\u5408\u578b\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c145\u5e74\u4f1a (\u798f\u5ca1) 2025\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6dfa\u96db \u7a42\u4e43\u82b1, \u4e2d\u5cf6 \u4e00\u78e8, \u9577\u8c37\u5ddd \u62d3\u771f, \u85e4\u672c \u88d5\u4e4b, \u6751\u4e0a \u660c\u53f2, \u5927\u6c5f \u4e00\u5f18, \u8c4a\u5d8b \u539a\u53f2, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u65b0\u898f<sup>211<\/sup>At\u6a19\u8b58PSMA\u6a19\u7684\u85ac\u5264\u306e\u958b\u767a\u3092\u76ee\u7684\u3068\u3057\u305f<sup>125<\/sup>I\u6a19\u8b58\u4f53\u306b\u3088\u308b\u57fa\u790e\u7684\u8a55\u4fa1<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c145\u5e74\u4f1a (\u798f\u5ca1) 2025\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6570\u591a \u4f38\u7d00, \u4e2d\u5cf6 \u4e00\u78e8, \u5782\u6c34 \u52c7\u592a, \u771e\u77e2 \u5553\u53f2, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u65b0\u898f\u30ea\u30f3\u30ab\u30fc\u6280\u8853\u3092\u5229\u7528\u3057\u305f<sup>111<\/sup>In\/<sup>225<\/sup>Ac\u6a19\u8b58PSMA\u6a19\u7684\u30e9\u30b8\u30aa\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c145\u5e74\u4f1a (\u798f\u5ca1) 2025\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u8d64\u5742 \u8cb4\u6d69, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30d0\u30a4\u30aa\u30a2\u30c3\u30bb\u30a4\u3078\u306e\u5fdc\u7528\u3092\u53ef\u80fd\u3068\u3059\u308b\u6c34\u6eb6\u6027\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u6a19\u7684\u86cd\u5149\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c145\u5e74\u4f1a (\u798f\u5ca1) 2025\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u67cf\u5c71 \u9678\u6597, \u6e21\u908a \u88d5\u4e4b, \u8d64\u5742 \u8cb4\u6d69, \u85e4\u672c \u88d5\u4e4b, \u6751\u4e0a \u660c\u53f2, \u5927\u6c5f \u4e00\u5f18, \u8c4a\u5d8b \u539a\u53f2, \u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u9ad8LET\u8377\u96fb\u7c92\u5b50\u7dda\u306b\u3088\u308b\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u51dd\u96c6\u6291\u5236\u4f5c\u7528\u306b\u95a2\u3059\u308b\u57fa\u790e\u7684\u8a55\u4fa1<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c145\u5e74\u4f1a (\u798f\u5ca1) 2025\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c71\u6839 \u62d3\u771f, \u6570\u591a \u4f38\u7d00, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u816b\u760d\u6ede\u7559\u6027\u306e\u5411\u4e0a\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898f\u30bd\u30de\u30c8\u30b9\u30bf\u30c1\u30f3\u53d7\u5bb9\u4f532\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c145\u5e74\u4f1a (\u798f\u5ca1) 2025\u5e743\u670826\u65e5\u301c29\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u304c\u3093\u306e\u653e\u5c04\u7dda\u5185\u7528\u7642\u6cd5\u306e\u767a\u5c55\u306b\u5411\u3051\u305f\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u306e\u958b\u767a<\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c13\u56de BRIGHT symposium<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u5fb3\u5cf6)\u00a0 <\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2025\u5e742\u67085\u65e5<\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2024 (\u8ad6\u6587)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Ishizaka Y, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Structure-Affinity-Pharmacokinetics Relationships of Novel <\/span><span style=\"font-size: 14px;text-indent: 1em\"><sup>18<\/sup>F\u2010Labeled 1,4-Diazepane Derivatives for Orexin 1 Receptor Imaging<\/span><br \/>\n<\/span><\/span><\/span><\/span><span lang=\"EN-US\"><em>J. Med. Chem. <\/em>67<span class=\"Apple-style-span\">(21) 18781-18793 (2024)<\/span><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: <\/span><span style=\"font-size: 14px;text-indent: 1em\">10.1021\/acs.jmedchem.4c01090<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Nakano D, Watanabe H, Saito K, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">A Novel Bifunctional Chelating Agent for Tyrosine-Specific Radiolabeling of Peptides and Proteins<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Bioconjug. Chem. <\/em>35(10) 1577-1586 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.bioconjchem.4c00363<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Yamaguchi K, Kazuta N, Tsuchihashi S, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Structure-affinity-pharmacokinetics relationships of <sup>111<\/sup>In-labeled PSMA-targeted ligands with different albumin binders<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Nucl. Med. Biol.<\/em> 138-139 108945 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.nucmedbio.2024.108945<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Jinda H, Watanabe H, Nakashima K, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Application of microfluidic devices for automated two-step radiolabeling of antibodies<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span lang=\"EN-US\"><em>J. Labelled Comp. Radiopharm<\/em>. 67(10) 341-348 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1002\/jlcr.4119<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Shimizu Y, Ando M, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Novel technetium-99m-labeled bivalent PSMA-targeting probe based on a hydroxamamide chelate for the diagnosis of prostate cancer<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Ann. Nucl. Med. <\/em>38(10) 847-851 (2024)<em><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/em><span style=\"font-size: 14px;text-indent: 1em\">DOI: 10.1007\/s12149-024-01959-9<\/span><br \/>\n<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\uff08\u516c\u793e\uff09\u65e5\u672c\u30a2\u30a4\u30bd\u30c8\u30fc\u30d7\u5354\u4f1a\u3000\u7406\u5de5\u30fb\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u90e8\u4f1a\u3000\u653e\u5c04\u7dda\u7167\u5c04\u6a19\u7684\u5206\u5b50\u63a2\u7d22\u5c02\u9580\u59d4\u54e1\u4f1a\uff08\u6e05\u91ce\u6cf0\u3001\u5c0f\u5ddd\u7f8e\u9999\u5b50\u3001\u98ef\u585a\u5927\u8f14\u3001\u5927\u5cf6\u5eb7\u5b8f\u3001\u5927\u539f\u9ebb\u5e0c\u3001\u5c0f\u91ce\u6b63\u535a\u3001\u9234\u6728\u535a\u5143\u3001\u6c38\u6d25\u5f18\u592a\u90ce\u3001\u6df5\u4e0a\u525b\u5fd7\uff09<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u77ed\u98db\u7a0b\u653e\u5c04\u7dda\u3092\u5229\u7528\u3057\u305f\u6838\u533b\u5b66\u6cbb\u7642\u85ac\u5264\u306e\u958b\u767a\u72b6\u6cc1<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><em>RADIOISOTOPES<\/em>, 73 271-290 (2024)<span lang=\"EN-US\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: <\/span><span style=\"font-size: 14px;text-indent: 1em\">10.3769\/radioisotopes.73.271<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Kazuta N, Nakashima K, Watanabe H, Ono M.<br \/>\n<span class=\"Apple-style-span\">Effect of Linker Entities on Pharmacokinetics of <sup>111<\/sup>In-Labeled Prostate-Specific Membrane Antigen-Targeting Ligands with an Albumin Binder<\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>ACS Pharmacol. Transl. Sci. <\/em>7(8) 2401-2413 (2024)<br \/>\nDOI: 10.1021\/acsptsci.4c00257<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Okuyama C, Higashi T, Ishizu K, Oishi N, Kusano K, Ito M, Kagawa S, Okina T, Suzuki N, Hasegawa H, Nagahama Y, Watanabe H, Ono M, Yamauchi H.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">New objective simple evaluation method\uff53 of amyloid PET\/CT using whole brain histogram and Top20\uff05-Map<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Ann. Nucl. Med.<\/em> 38(9) 763-773 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1007\/s12149-024-01956-y<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Akasaka T, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Combined strategies for optimizing BODIPY-based near-infrared fluorescent probe targeting A\u03b2 oligomers<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Sens. Actuators B Chem. <\/em>417 136132 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.snb.2024.136132<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Nagashima K, Watanabe H, Akasaka T, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Development of triphenylmethane dyes for in vivo fluorescence imaging of A\u03b2 oligomers<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>ACS Chem. Neurosci.<\/em> 15(11) 2233-2242 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acschemneuro.4c00053<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Jinda H, Nakashima K, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and evaluation of cathepsin B-recognizing trifunctional chelating agent to improve tumor retention of radioimmunoconjugates\u00a0<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span lang=\"EN-US\"><em>J. Labelled Comp. Radiopharm<\/em>. 67(8) 995-304 (2024)\u00a0<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1002\/jlcr.4112<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Onoue R, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Development of novel bi-modal agents based on near-infrared BODIPY-conjugated Hoechst derivatives for combined use in Auger electron and photodynamic cancer therapy<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>ACS Pharmacol. Transl. Sci. <\/em>7(5) 1395-1403 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acsptsci.4c00035<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Kazuta N, Tsuchihashi S, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Fundamental Evaluation Regarding the Relationship between Albumin-binding and Tumor Accumulation of PSMA-targeting Radioligands<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Ann. Nucl. Med.<\/em> 38(7) 574-583 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1007\/s12149-024-01930-8<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Tsuchihashi S, Nakashima K, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and Evaluation of Novel Trifunctional Chelating Agents for Pretargeting Approach Using Albumin Binder to Improve Tumor Accumulation<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Nucl. Med. Biol.<\/em> 132-133 108911 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.nucmedbio.2024.108911<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Watanabe H, Ikawa M, Kakae M, Shirakawa H, Kaneko S, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and biological evaluation of radioiodinated benzoxazole and benzothiazole derivatives for imaging myelin in multiple sclerosis<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Bioorg. Med. Chem. Lett.<\/em> 103 129691 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.bmcl.2024.129691<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u91d1\u5c5e\u30ad\u30ec\u30fc\u30c8\u3092\u57fa\u76e4\u3068\u3057\u305f<sup>111<\/sup>In\/<sup>225<\/sup>Ac\u6a19\u8b58\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\">\u5927\u962a\u5927\u5b66\u653e\u5c04\u7dda\u79d1\u5b66\u57fa\u76e4\u6a5f\u69cb\u300c\u653e\u5c04\u7dda\u79d1\u5b66\u30d5\u30ed\u30f3\u30c6\u30a3\u30a2\u301c\u5b5f\u5b97\u7af9\u301c2023 \u7b2c5\u53f7\u300d, 20<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Radiotheranostics Based on Chemical Control of Radioactivity Pharmacokinetics<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>YAKUGAKU ZASSHI<\/em> 144 291-297 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1248\/yakushi.23-00168-3<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Saito H, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and biological evaluation of novel <sup>18<\/sup>F-labeled 2,4-diaminopyrimidine derivatives for detection of ghrelin receptor in the brain<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Bioorg. Med. Chem. Lett.<\/em> 99 129625 (2024)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.bmcl.2024.129625 <\/span><\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2024 (\u8457\u66f8\u7b49)<\/h2>\n<ol>\n<li><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u5c0f\u91ce \u6b63\u535a\uff0c\u4e45\u4e0b \u88d5\u53f8<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><br \/>\n<\/span><\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5275\u7acb\uff16\uff10\u5468\u5e74\u8a18\u5ff5\u8a8c\u300c\u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u7814\u7a76\u4f1a\u300d<\/span><\/span><\/span><\/span><\/span><br \/>\n\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u3001\uff12\uff10\uff12\uff14\u5e74\uff11\uff10\u6708<\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2024 (\u5b66\u4f1a\u767a\u8868)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Takuma Hasegawa, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Novel radioligands with tumor-residualizing properties for theranosctics of prostate cancer<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c\uff12\u56de\u77ed\u5bff\u547dRI\u5229\u7528\u7814\u7a76\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u5927\u962a)\u00a0 <\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2024\u5e7412\u670813\u65e5\u301c14\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Nobuki Kazuta, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Development of novel radioligands targeting prostate-specific membrane antigen for diagnosis and therapy of prostate cancer<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th Seoul-Kyoto-Osaka Joint Symposium on Pharmaceutical Sciences for Young Scientists (Seoul, Korea) November 18-19, 2024<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\">\u9f4b\u85e4 \u6d69\u8f14, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px\">FAP-2286\u306e\u816b\u760d\u6ede\u7559\u6027\u306e\u5411\u4e0a\u3092\u76ee\u7684\u3068\u3057\u305fFAP\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><br \/>\n\u7b2c64\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092024\u5e7411\u67087\u65e5\u301c9\u65e5<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\">\u571f\u6a4b \u660c\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px\">\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u3092\u6709\u3059\u308b\u65b0\u898f\u30ac\u30b9\u30c8\u30ea\u30f3\u653e\u51fa\u30da\u30d7\u30c1\u30c9\u53d7\u5bb9\u4f53\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/span><br \/>\n\u7b2c64\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092024\u5e7411\u67087\u65e5\u301c9\u65e5<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\">\u6570\u591a \u4f38\u7d00, <\/span><\/span>\u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">\u65b0\u898f\u30ea\u30f3\u30ab\u30fc\u6280\u8853\u3092\u7528\u3044\u305fPSMA\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c64\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092024\u5e7411\u67087\u65e5\u301c9\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u8fbb \u7965\u592a\u90ce, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">\u7d30\u80de\u5185\u6ede\u7559\u578b\u91d1\u5c5eRI\u6a19\u8b58\u5264\u306e\u6297\u4e2d\u76ae\u816b\u6297\u4f53\u3078\u306e\u5fdc\u7528<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c64\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092024\u5e7411\u67087\u65e5\u301c9\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b, \u77f3\u5742 \u512a\u8863, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">1,4-\u30b8\u30a2\u30bc\u30d1\u30f3\u9aa8\u683c\u3092\u57fa\u76e4\u3068\u3057\u305f\u30aa\u30ec\u30ad\u30b7\u30f31\u53d7\u5bb9\u4f53\u6a19\u7684PET\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c64\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u6a2a\u6d5c\uff092024\u5e7411\u67087\u65e5\u301c9\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u4e2d\u91ce \u5927\u6a39, \u6e21\u908a \u88d5\u4e4b, \u9f4b\u85e4 \u6d69\u8f14, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30c8\u30ea\u30a2\u30b6\u30d6\u30bf\u30b8\u30a8\u30f3\u9aa8\u683c\u3092\u7528\u3044\u305f\u30c1\u30ed\u30b7\u30f3\u7279\u7570\u7684\u4e8c\u5b98\u80fd\u6027\u30ad\u30ec\u30fc\u30c8\u8a66\u85ac\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c74\u56de \u65e5\u672c\u85ac\u5b66\u4f1a\u95a2\u897f\u652f\u90e8\u7dcf\u4f1a\u30fb\u5927\u4f1a (\u5175\u5eab) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2024\u5e7410\u67085\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u9577\u8c37\u5ddd \u62d3\u771f, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u524d\u7acb\u817a\u304c\u3093\u306e\u9ad8\u7cbe\u5ea6\u8a3a\u65ad\u3092\u76ee\u7684\u3068\u3057\u305f\u816b\u760d\u6ede\u7559\u578b\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c74\u56de \u65e5\u672c\u85ac\u5b66\u4f1a\u95a2\u897f\u652f\u90e8\u7dcf\u4f1a\u30fb\u5927\u4f1a (\u5175\u5eab) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2024\u5e7410\u67085\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u67cf\u5c71 \u9678\u6597, \u6e21\u908a \u88d5\u4e4b, \u8d64\u5742 \u8cb4\u6d69, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u5206\u5c90\u69cb\u9020\u5c0e\u5165\u306b\u3088\u308b A\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u6a19\u7684\u8fd1\u8d64\u5916\u86cd\u5149\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c74\u56de \u65e5\u672c\u85ac\u5b66\u4f1a\u95a2\u897f\u652f\u90e8\u7dcf\u4f1a\u30fb\u5927\u4f1a (\u5175\u5eab) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2024\u5e7410\u67085\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Shohei Tsuchihashi, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Development of novel radiotheranostic agents with albumin binder for cancer treatment<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c4\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2024\u5e749\u670825\u65e5\u301c27\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Takuma Hasegawa, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Development of tumor-residualizing radiopharmaceuticals for theranostics of prostate cancer<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c4\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2024\u5e749\u670825\u65e5\u301c27\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Shohei Tsuchihashi, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Development of novel pretargeting strategy for nuclear imaging and targeted radionuclide therapy of cancer<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c4\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2024\u5e749\u670825\u65e5\u301c27\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Nobuki Kazuta, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Novel PSMA-targeting radioligands with improved pharmacokinetics for diagnosis and therapy of prostate cancer<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c4\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2024\u5e749\u670825\u65e5\u301c27\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Kosuke Saito, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Synthesis and evaluation of c-Met-targeting radiopharmaceuticals based on peptide ligands for cancer diagnosis and therapy<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c4\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2024\u5e749\u670825\u65e5\u301c27\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Daiki Nakano, Hiroyuki Watanabe, Kosuke Saito, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Novel Tyrosine-Specific Radiometal Labeling Method Using Triazabutadiene Scaffold<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Nobuki Kazuta, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Impact of linker on pharmacokinetics of PSMA-targeting radioligands with albumin binder<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Shohei Tsuchihashi, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Application of albumin binder to pretargeting strategy for increasing tumor uptake<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><\/span><span style=\"color: #333333\"><br \/>\n<\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Kosuke Saito, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Fundamental study on the development of c-Met-targeting radiopharmaceuticals for the diagnosis and treatment of cancer<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><br \/>\n<\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Takahiro Akasaka, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Development of Bimodal Radioactive\/Fluorescent Imaging Probe Targeting A\u03b2 Oligomers<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><br \/>\n<\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Development of positively-charged chelating agents that control the biodistribution of radioimmunoconjugates<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><br \/>\n<\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Hiroki Jinda, Kazuma Nakashima, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Novel cathepsin B substrate-containing chelating agent to enhance intracellular retention of radioimmunoconjugates in tumor<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Hiroyuki Watanabe<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Development of Bimodal Agents for Combined Use in Auger Electron and Photodynamic Cancer Therapy<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Current Status of Radiopharmaceutical Sciences in Japan 2024 (Plenary Lecture)<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\">The 12th China-Japan-Korea Symposium on Radiopharmaceutical Sciences (CJKSRS 2024) (Kanazawa, Japan) <span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">September<\/span> 19-20, 2024<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u5c71\u53e3 \u6075\u8056, \u6570\u591a \u4f38\u7d00, \u571f\u6a4b \u660c\u5e73, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u306b\u7740\u76ee\u3057\u305f\u524d\u7acb\u817a\u7279\u7570\u7684\u819c\u6297\u539f\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u69cb\u9020-\u89aa\u548c\u6027-\u52d5\u614b\u76f8\u95a2<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c21\u56de\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u306e\u305f\u3081\u306e\u30d5\u30a3\u30b8\u30ab\u30eb\u30fb\u30d5\u30a1\u30fc\u30de\u30d5\u30a9\u30fc\u30e9\u30e0 (\u795e\u5948\u5ddd) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2024\u5e748\u670822\u65e5, 23\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u4e0b\u539f \u6ec9\u7a00, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u653e\u5c04\u6027\u6a19\u8b58\u6297\u4f53\u306e\u4f53\u5185\u52d5\u614b\u5236\u5fa1\u3092\u76ee\u7684\u3068\u3057\u305f\u30ab\u30c1\u30aa\u30f3\u6027\u30ad\u30ec\u30fc\u30c8\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c21\u56de\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u306e\u305f\u3081\u306e\u30d5\u30a3\u30b8\u30ab\u30eb\u30fb\u30d5\u30a1\u30fc\u30de\u30d5\u30a9\u30fc\u30e9\u30e0 (\u795e\u5948\u5ddd) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2024\u5e748\u670822\u65e5, 23\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u4e00\u30ce\u702c \u8cb4\u5141, \u79cb\u8449 \u5b8f\u6a39, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">HER2\u6a19\u7684\u30d0\u30a4\u30d1\u30e9\u30c8\u30d4\u30c3\u30af\u6297\u4f53\u3092\u57fa\u76e4\u3068\u3057\u305f\u653e\u5c04\u6027\u6297\u4f53\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c21\u56de\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u306e\u305f\u3081\u306e\u30d5\u30a3\u30b8\u30ab\u30eb\u30fb\u30d5\u30a1\u30fc\u30de\u30d5\u30a9\u30fc\u30e9\u30e0 (\u795e\u5948\u5ddd) <span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2024\u5e748\u670822\u65e5, 23\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u8a8d\u77e5\u75c7\u30fb\u304c\u3093\u306e\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u306b\u8cc7\u3059\u308b\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c61\u56de\u30a2\u30a4\u30bd\u30c8\u30fc\u30d7\u30fb\u653e\u5c04\u7dda\u7814\u7a76\u767a\u8868\u4f1a (\u6771\u4eac) 2024\u5e747\u67083\u65e5\u301c\uff15\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">Hiroyuki Watanabe, Ryotaro Onoue, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"text-indent: 1em\">Development of novel bi-modal agents for combination use of Auger electron therapy and photodynamic therapy<\/span><br \/>\n<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\">Society of Nuclear Medicine and Molecular Imaging 2024 Annual Meeting (Toronto, Canada) June<span class=\"Apple-style-span\"> 8-11, 2024<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u6570\u591a \u4f38\u7d00, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">Structure-affinity-pharmacokinetics relationship of <sup>111<\/sup>In-labeled prostate-specific membrane antigen-targeting radioligands<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c33\u56de\u91d1\u5c5e\u306e\u95a2\u4e0e\u3059\u308b\u751f\u4f53\u95a2\u9023\u53cd\u5fdc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 (\u5ca1\u5c71) 2024\u5e746\u67087\u65e5, 8\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u751a\u7530 \u6d38\u5e0c, \u6e21\u908a \u88d5\u4e4b, \u4e2d\u5cf6 \u4e00\u78e8, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">Application of microfluidic devices for automated two-step labeling of antibodies with radiometal<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c33\u56de\u91d1\u5c5e\u306e\u95a2\u4e0e\u3059\u308b\u751f\u4f53\u95a2\u9023\u53cd\u5fdc\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 (\u5ca1\u5c71) 2024\u5e746\u67087\u65e5, 8\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u4e2d\u91ce \u5927\u6a39, \u6e21\u908a \u88d5\u4e4b, \u9f4b\u85e4 \u6d69\u8f14, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u30c8\u30ea\u30a2\u30b6\u30d6\u30bf\u30b8\u30a8\u30f3\u9aa8\u683c\u3092\u7528\u3044\u305f\u65b0\u898f\u30c1\u30ed\u30b7\u30f3\u7279\u7570\u7684\u91d1\u5c5eRI\u6a19\u8b58\u6cd5\u306e\u958b\u767a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c18\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a (\u6771\u4eac) 2024\u5e745\u670823\u65e5, 24\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u8d64\u5742 \u8cb4\u6d69, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">A\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u6a19\u7684\u8fd1\u8d64\u5916\u86cd\u5149\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u306e\u9ad8\u7cbe\u5ea6\u5316\u3092\u76ee\u7684\u3068\u3057\u305fBODIPY\u8a98\u5c0e\u4f53\u306e\u69cb\u9020\u6700\u9069\u5316<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c18\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a (\u6771\u4eac) 2024\u5e745\u670823\u65e5, 24\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b, \u9577\u5d8b \u6d69\u592a\u6717, \u8d64\u5742 \u8cb4\u6d69, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u30c8\u30ea\u30d5\u30a7\u30cb\u30eb\u30e1\u30bf\u30f3\u69cb\u9020\u3092\u57fa\u76e4\u3068\u3057\u305f\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u6a19\u7684\u86cd\u5149\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c18\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a (\u6771\u4eac) 2024\u5e745\u670823\u65e5, 24\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">PET\u691c\u67fb\u85ac\u306e\u88fd\u9020\u30fb\u7ba1\u7406 (PET\u7814\u4fee\u30bb\u30df\u30ca\u30fc)<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c24\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u6625\u5b63\u5927\u4f1a (\u30aa\u30f3\u30e9\u30a4\u30f3) 2024\u5e744\u670825\u65e5\u301c6\u67084\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u8d64\u5742 \u8cb4\u6d69, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">A\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u6a19\u7684\u8fd1\u8d64\u5916\u86cd\u5149\u30d7\u30ed\u30fc\u30d6\u3068\u3057\u3066\u306e\u30c1\u30aa\u30d5\u30a7\u30f3\u7f6e\u63dbBODIPY\u8a98\u5c0e\u4f53\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c144\u5e74\u4f1a (\u6a2a\u6d5c) 2024\u5e743\u670828\u65e5\u301c31\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b, \u5c3e\u4e0a \u907c\u592a\u90ce, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u304c\u3093\u306e\u30aa\u30fc\u30b8\u30a7\u6cbb\u7642\u304a\u3088\u3073\u5149\u7dda\u529b\u5b66\u7642\u6cd5\u306e\u4f75\u7528\u3092\u53ef\u80fd\u306b\u3059\u308b\u4e8c\u6a5f\u80fd\u6027BODIPY\u8a98\u5c0e\u4f53\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c144\u5e74\u4f1a (\u6a2a\u6d5c) 2024\u5e743\u670828\u65e5\u301c31\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u9f4b\u85e4 \u6d69\u8f14, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u304c\u3093\u306e\u8a3a\u65ad\u30fb\u6cbb\u7642\u3092\u76ee\u7684\u3068\u3057\u305fc-Met\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a\u306b\u95a2\u3059\u308b\u57fa\u790e\u7684\u8a55\u4fa1<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c144\u5e74\u4f1a (\u6a2a\u6d5c) 2024\u5e743\u670828\u65e5\u301c31\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u653e\u5c04\u6027\u91d1\u5c5e\u6a19\u8b58\u6297\u4f53\u306e\u816b\u760d\u96c6\u7a4d\u6027\u306e\u5411\u4e0a\u3092\u76ee\u7684\u3068\u3057\u305f\u4e2d\u5206\u5b50PEG\u542b\u6709\u30ad\u30ec\u30fc\u30c8\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><br \/>\n<span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c144\u5e74\u4f1a (\u6a2a\u6d5c) 2024\u5e743\u670828\u65e5\u301c31\u65e5<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u751a\u7530 \u6d38\u5e0c, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u653e\u5c04\u6027\u6297\u4f53\u85ac\u5264\u306e\u816b\u760d\u6ede\u7559\u6027\u306e\u5411\u4e0a\u3092\u76ee\u7684\u3068\u3057\u305f\u30ab\u30c6\u30d7\u30b7\u30f3B\u8a8d\u8b58\u6027\u30ad\u30ec\u30fc\u30c8\u5264\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c144\u5e74\u4f1a (\u6a2a\u6d5c) 2024\u5e743\u670828\u65e5\u301c31\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u6570\u591a \u4f38\u7d00, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">PSMA\u6a19\u7684\u653e\u5c04\u6027\u85ac\u5264\u306e\u30a2\u30eb\u30d6\u30df\u30f3\u7d50\u5408\u6027\u3068\u816b\u760d\u96c6\u7a4d\u6027\u306e\u95a2\u9023\u306b\u95a2\u3059\u308b\u57fa\u790e\u7684\u8a55\u4fa1<\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\"><span class=\"Apple-style-span\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c144\u5e74\u4f1a (\u6a2a\u6d5c) 2024\u5e743\u670828\u65e5\u301c31\u65e5<\/span><\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2023 (\u8ad6\u6587)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Onoue R, Watanabe H, Ono M.<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and biological evaluation of bi-modal BODIPY-conjugated Hoechst applicable for Auger-electron and photodynamic cancer therapy<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Bioorg. Med. Chem. Lett. <\/em>96 129534 (2023)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.bmcl.2023.129534 <\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Akasaka T, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><em>In vivo<\/em> Near-Infrared Fluorescence Imaging Selective for Soluble Amyloid \u03b2 Aggregates Using y-Shaped BODIPY Derivative<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span lang=\"EN-US\"><em>J. Med. Chem.<\/em> 66(20) 14029-14046 (2023)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.jmedchem.3c01057<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u30fb\u6838\u533b\u5b66\u5206\u91ce\u306b\u304a\u3051\u308b\u85ac\u5b66\u7cfb\u4eba\u6750\u80b2\u6210\u00a0<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>\u653e\u5c04\u5316\u5b66<\/em> 48 41-44 (2023)<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Nakashima K, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Development of Novel Trifunctional Chelating Agents That Enhance Tumor Retention of Radioimmunoconjugates<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span lang=\"EN-US\"><em>J. Med. Chem.<\/em> 66(18) 12812-12827 (2023)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.jmedchem.3c00472 <\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Tsuchihashi S, Nakashima K, Tarumizu Y, Ichikawa H, Jinda H, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Development of Novel <sup>111<\/sup>In\/<sup>225<\/sup>Ac-Labeled Agent Targeting PSMA for Highly Efficient Cancer Radiotheranostics<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span lang=\"EN-US\"><em>J. Med. Chem.<\/em> 66(12) 8043-8053 (2023)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.jmedchem.3c00346 <\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Kazuta N, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and Evaluation of <sup>111<\/sup>In-labeled Tetrapeptide-based Compounds as SPECT Imaging Probes Targeting Granzyme B<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span lang=\"EN-US\"><em>J. Labelled Comp. Radiopharm.<\/em> 66(10) 298-307 (2023)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1002\/jlcr.4045<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u30a2\u30df\u30ed\u30a4\u30c9\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5264\u306e\u958b\u767a\u306b\u304a\u3051\u308b\u85ac\u5b66\u7684\u8ca2\u732e<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>\u6838\u533b\u5b66\u6280\u8853<\/em>\u00a043 45-49 (2023)<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Watanabe H, Ide T, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and characterization of novel radioiodinated triazole-pyrolidine derivative to detect orexin 2 receptor in the brain<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Chem. Pharm.\u00a0Bull.<\/em> 71(3) 234-239 (2023)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1248\/cpb.c22-00770<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Onoue R, Watanabe H, Ono M.<\/span><\/span><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Hoechst-tagged radioiodinated BODIPY derivative for Auger-electron cancer therapy<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span lang=\"EN-US\"><em>Chem. Commun.<\/em> 59 928-931 (2023)<span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1039\/d2cc05405a<\/span><\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2023 (\u5b66\u4f1a\u767a\u8868)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">\u653e\u5c04\u6027\u6297\u4f53\u85ac\u5264\u306e\u816b\u760d\u6ede\u7559\u6027\u306e\u5411\u4e0a\u3092\u4f01\u56f3\u3057\u305f\u65b0\u898fPEG\u5316\u30ad\u30ec\u30fc\u30c8\u5264\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c63\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u5927\u962a\uff09 2023\u5e7411\u670816\u65e5\u301c18\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u571f\u6a4b \u660c\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u5782\u6c34 \u52c7\u592a, \u5e02\u5ddd \u6d69\u7ae0, \u751a\u7530 \u6d38\u5e0c, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">\u65b0\u898f<sup>111<\/sup>In\/<sup>225<\/sup>Ac\u6a19\u8b58PSMA\u6a19\u7684\u85ac\u5264\u3092\u7528\u3044\u305f\u9ad8\u52b9\u7387\u30e9\u30b8\u30aa\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c63\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u5927\u962a\uff09 2023\u5e7411\u670816\u65e5\u301c18\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">\u653e\u5c04\u7dda\u5185\u7528\u7642\u6cd5\u304a\u3088\u3073\u5149\u7dda\u529b\u5b66\u7642\u6cd5\u3092\u53ef\u80fd\u3068\u3059\u308bbi-modal\u85ac\u5264\u306e\u958b\u767a<span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"> (\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff09<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c63\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u5927\u962a\uff09 2023\u5e7411\u670816\u65e5\u301c18\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Shohei Tsuchihashi, Kazuma Nakashima, Yuta Tarumizu, Hiroaki Ichikawa, Hiroki Jinda, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Development of novel radiotheranostic agent targeting prostate-specific membrane antigen for highly efficient prostate cancer therapy<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c3\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2023\u5e749\u670827\u65e5\u301c29\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Takahiro Akasaka, Hiroyuki Watanabe, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">In vivo near-infrared imaging targeting amyloid \u03b2 oligomers in model mouse of Alzheimers disease<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c3\u56de\u7814\u7a76\u4ea4\u6d41\u30b5\u30ed\u30f3<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u4eac\u90fd)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2023\u5e749\u670827\u65e5\u301c29\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">3\u5b98\u80fd\u6027\u91d1\u5c5e\u914d\u4f4d\u5b50DOTADG\u3092\u7528\u3044\u305f\u30e9\u30b8\u30aa\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u7528\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c6\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5206\u79d1\u4f1a \u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u7814\u7a76\u4f1a\/<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c2\uff12<\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u56de\u653e\u5c04\u6027\u533b\u85ac\u54c1\u30fb\u753b\u50cf\u8a3a\u65ad\u85ac\u7814\u7a76\u4f1a<\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u5343\u8449)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2023\u5e749\u67089\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u571f\u6a4b \u660c\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u816b\u760d\u96c6\u7a4d\u5411\u4e0a\u3092\u76ee\u7684\u3068\u3057\u305f\u591a\u6a5f\u80fd\u6027\u30ad\u30ec\u30fc\u30c8\u30ea\u30f3\u30ab\u30fc\u306e\u30d7\u30ec\u30bf\u30fc\u30b2\u30c6\u30a3\u30f3\u30b0\u6cd5\u3078\u306e\u5fdc\u7528<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c6\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5206\u79d1\u4f1a \u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u7814\u7a76\u4f1a\/<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c2\uff12<\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u56de\u653e\u5c04\u6027\u533b\u85ac\u54c1\u30fb\u753b\u50cf\u8a3a\u65ad\u85ac\u7814\u7a76\u4f1a<\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u5343\u8449)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2023\u5e749\u67089\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u8d64\u5742 \u8cb4\u6d69,\u00a0<\/span><\/span>\u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u3092\u6a19\u7684\u3068\u3057\u305f\u65b0\u898f\u8fd1\u8d64\u5916\u86cd\u5149\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u6cd5\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c20\u56de\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u306e\u305f\u3081\u306e\u30d5\u30a3\u30b8\u30ab\u30eb\u30fb\u30d5\u30a1\u30fc\u30de\u30d5\u30a9\u30fc\u30e9\u30e0 (\u4eac\u90fd)\u00a0<span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2023\u5e748\u670831\u65e5, 9\u67081\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u9f4b\u85e4 \u6674\u9999, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u4e2d\u67a2\u30b0\u30ec\u30ea\u30f3\u53d7\u5bb9\u4f53\u306ePET\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898f<sup>18<\/sup>F\u6a19\u8b58\u30b8\u30a2\u30df\u30ce\u30d4\u30ea\u30df\u30b8\u30f3\u8a98\u5c0e\u4f53\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c20\u56de\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u306e\u305f\u3081\u306e\u30d5\u30a3\u30b8\u30ab\u30eb\u30fb\u30d5\u30a1\u30fc\u30de\u30d5\u30a9\u30fc\u30e9\u30e0 (\u4eac\u90fd)\u00a0<span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2023\u5e748\u670831\u65e5, 9\u67081\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u30a2\u30df\u30ed\u30a4\u30c9PET\u85ac\u5264\u958b\u767a\u306e\u904e\u53bb\u30fb\u73fe\u5728\u30fb\u672a\u6765<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c\uff14\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a \u95a2\u6771\u7532\u4fe1\u8d8a\u652f\u90e8\u4f1a (\u30aa\u30f3\u30e9\u30a4\u30f3) 2023\u5e748\u670821\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u91d1\u5c5e\u30ad\u30ec\u30fc\u30c8\u3092\u57fa\u76e4\u3068\u3057\u305f<sup>111<\/sup>In\/<sup>225<\/sup>Ac\u6a19\u8b58\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u77ed\u5bff\u547dRI\u5229\u7528\u7814\u7a76\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0 (\u5927\u962a) 2023\u5e748\u67082\u65e5\u301c\uff13\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u3092\u5fd7\u5411\u3057\u305f\u6b21\u4e16\u4ee3\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a\u7814\u7a76<span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"> (\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff09<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c\uff13\uff15\u56de\u30d0\u30a4\u30aa\u30e1\u30c7\u30a3\u30ab\u30eb\u5206\u6790\u79d1\u5b66\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0(BMAS2023) (\u672d\u5e4c) 2023\u5e747\u670828\u65e5\u301c29\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u653e\u5c04\u7dda\u304c\u62d3\u304f\u65b0\u305f\u306a\u8a3a\u65ad\u30fb\u6cbb\u7642<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c\uff13\uff11\u56de\u5343\u8449\u5927\u5b66\u85ac\u5b66\u90e8 \u85ac\u53cb\u4f1a\u751f\u6daf\u6559\u80b2\u30bb\u30df\u30ca\u30fc\u30fb\u5bae\u6728\u9ad8\u660e\u8a18\u5ff5\u8b1b\u6f14\u4f1a (\u5343\u8449) 2023\u5e747\u67088\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u653e\u5c04\u6027\u533b\u85ac\u54c1\u306e\u958b\u767a\u7814\u7a76\u306b\u304a\u3051\u308bRI\u5229\u7528<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u95a2\u897f\u533b\u79d1\u5927\u5b66 RI\u8b1b\u7fd2\u4f1a \u7279\u5225\u8b1b\u6f14 (\u5927\u962a) 2023\u5e746\u670822\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u8d64\u5742 \u8cb4\u6d69, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">A\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u30d7\u30ed\u30fc\u30d6\u3068\u3057\u3066\u306eBODIPY\u8a98\u5c0e\u4f53\u306e\u6709\u7528\u6027\u8a55\u4fa1<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c17\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a (\u4ed9\u53f0) 2023\u5e746\u67088\u65e5, 9\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">PET\u691c\u67fb\u85ac\u306e\u88fd\u9020\u30fb\u7ba1\u7406 (PET\u7814\u4fee\u30bb\u30df\u30ca\u30fc)<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c23\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u6625\u5b63\u5927\u4f1a (\u30aa\u30f3\u30e9\u30a4\u30f3) 2023\u5e744\u670826\u65e5\u301c6\u67081\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u653e\u5c04\u6027\u6297\u4f53\u85ac\u5264\u306e\u4f53\u5185\u52d5\u614b\u5236\u5fa1\u3092\u76ee\u7684\u3068\u3057\u305f\u591a\u6a5f\u80fd\u6027\u30ad\u30ec\u30fc\u30c8\u8a66\u85ac\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\"><span class=\"Apple-style-span\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c143\u5e74\u4f1a (\u672d\u5e4c) 2023\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u8d64\u5742 \u8cb4\u6d69, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">BODIPY\u3092\u6bcd\u6838\u3068\u3057\u305f\u65b0\u898f\u30a2\u30df\u30ed\u30a4\u30c9\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u6a19\u7684\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a<\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\"><span class=\"Apple-style-span\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c143\u5e74\u4f1a (\u672d\u5e4c) 2023\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u653e\u5c04\u80fd\u52d5\u614b\u306e\u5316\u5b66\u5236\u5fa1\u3092\u57fa\u76e4\u3068\u3057\u305f\u30e9\u30b8\u30aa\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"> (\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff09<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\"><span class=\"Apple-style-span\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c143\u5e74\u4f1a (\u672d\u5e4c) 2023\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u6e21\u908a \u88d5\u4e4b<\/span><br \/>\n<\/span><\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u75c5\u614b\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u306b\u6709\u7528\u306a\u6838\u533b\u5b66\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a (\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0\uff09<\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span class=\"Apple-style-span\">\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c143\u5e74\u4f1a (\u672d\u5e4c) 2023\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u30fb\u6838\u533b\u5b66\u5206\u91ce\u306b\u304a\u3051\u308b\u85ac\u5b66\u7cfb\u4eba\u6750\u80b2\u6210 (\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0)<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em\">\u65e5\u672c\u653e\u5c04\u5316\u5b66\u4f1a\u30fb\u6559\u80b2\u90e8\u4f1a\u3000\u7b2c2\u56de\u6559\u80b2\u30bb\u30df\u30ca\u30fc\u3000(\u7b51\u6ce2(\u30cf\u30a4\u30d6\u30ea\u30c3\u30c9))\u00a02023\u5e743\u67088\u65e5<\/span><\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2022 (\u8ad6\u6587)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Nakagawa K, Watanabe H, Kaide S, Ono M.<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Structure-Activity Relationships of Styrylquinoline and Styrylquinoxaline Derivatives as \u03b1-Synuclein Imaging Probes<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>ACS Med. Chem. Lett.\u00a0<\/em>13(10) 1598-1605 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acsmedchemlett.2c00279<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Kaide S, Watanabe H, Iikuni S, Hasegawa M, Ono M.<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and Evaluation of <sup>18<\/sup>F-Labeled Chalcone Analogue for Detection of \u03b1-Synuclein Aggregates in the Brain Using the Mouse Model<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>ACS Chem. Neurosci.<\/em> 13(20) 2982-2990 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acschemneuro.2c00473<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Nakashima K, Iikuni S, Watanabe H, Ono M.<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Application of the Chelator-based Clickable Radiotheranostic Platform to Moderate-molecular-weight Ligands<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>ACS Med. Chem. Lett.\u00a0<\/em>13(10) 1642-1647 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acsmedchemlett.2c00320<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Iikuni S, Ohara T, Watanabe H, Ono M.<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Structure-activity relationships and pharmacokinetics of <sup>111<\/sup>In-labeled glucagon-like peptide-1 receptor-targeting exendin-4 derivatives conjugated with albumin binder moieties<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>Mol. Pharm.<\/em> 19(8) 2832-2839 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.molpharmaceut.2c00201<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Iikuni S, Tarumizu Y, Tsuchihashi S, Ohara T, Watanabe H, Ono M.<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and evaluation of novel <sup>111<\/sup>In-labeled picolinic acid-based radioligands containing an albumin binder for development of radiotheranostic platform<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>Mol. Pharm.<\/em> 19(8) 2725-2736 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.molpharmaceut.2c00071<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u8702\u9808\u8cc0 \u6681\u5b50, \u6771 \u9054\u4e5f, \u7d30\u91ce \u771e, \u5c0f\u91ce \u6b63\u535a, \u4e0a\u539f \u77e5\u4e5f, \u897f\u6751 \u4f38\u592a\u90ce, \u6751\u4e0a \u5b66, \u6e21\u9089 \u30ea\u30e9, \u6839\u5143 \u8cb4\u884c, \u9ad8\u4e95 \u5e0c\u671b, \u897f\u689d \u6b66\u660e, \u6ce2\u591a\u91ce \u6b63, \u771e\u77e2 \u5553\u53f2, \u7af9\u68ee \u82f1\u6643, \u9999\u672c \u7965\u6c70, \u4f50\u6cbb \u82f1\u90ce.<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">FDA\u30ac\u30a4\u30c0\u30f3\u30b9\u300cOncology Therapeutic Radiopharmaceuticals: Nonclinical Studies and Labeling Recommendations Guidance for Industry\u300d\u306e\u65e5\u672c\u8a9e\u8a33\u304a\u3088\u3073\u88dc\u8db3\u8aac\u660e<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>\u30ec\u30ae\u30e5\u30e9\u30c8\u30ea\u30fc\u30b5\u30a4\u30a8\u30f3\u30b9\u5b66\u4f1a\u8a8c<\/em>, 12(2) 161-177 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.14982\/rsmp.12.161 <\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Akasaka T, Watanabe H, Kaide S, Iikuni S, Hasegawa M, Ono M.<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Synthesis and evaluation of novel radioiodinated phenylbenzofuranone derivatives as \u03b1-synuclein imaging probes<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>Bioorg. Med. Chem. Lett.\u00a0<\/em>64 128679 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.bmcl.2022.128679<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Iikuni S, Kamei I, Ohara T, Watanabe H, Ono M.<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">Development of an <sup>111<\/sup>In-Labeled Glucagon-Like Peptide-1 Receptor-Targeting Exendin-4 Derivative that Exhibits Reduced Renal Uptake<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>Mol. Pharm.<\/em> 19(3) 1019-1027 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acs.molpharmaceut.2c00068<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Saito K, Watanabe H, Iikuni S, Ono M.<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Development of novel <sup>67\/68<\/sup>Ga-labeled pyridyl benzofuran derivatives as islet amyloid imaging probes<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>Nucl. Med. Biol.<\/em> 106-107 72-79 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1016\/j.nucmedbio.2022.01.003<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Watanabe H, Maekawa R, Iikuni S, Kakae M, Matsuo N, Shirakawa H, Kaneko S, Ono M.<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Characterization of Radioiodinated Diaryl Oxadiazole Derivatives as SPECT Probes for Detection of Myelin in Multiple Sclerosis<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>ACS Chem. Neurosci.<\/em> 13(3) 363-369 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acschemneuro.1c00753<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Shimizu Y, Koyasu S, Suzukida M, Izumi K, Kidera E, Shindo T, Saga T, Ono M, Takaori-Kondo A, Nakamoto Y.<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Development of a novel Indium-111 radiolabeled mogamulizumab targeting CCR4 for imaging adult T-cell leukemia\/lymphoma in vivo<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>Ann. Nucl. Med.<\/em> 36(3) 319-326 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1007\/s12149-021-01706-4<\/span><\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Kaide S, Watanabe H, Iikuni S, Hasegawa M, Itoh K, Ono M.<\/span><\/span><\/span><span style=\"color: #333333\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\">Chalcone Analogue as New Candidate for Selective Detection of \u03b1-Synuclein Pathology<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;color: #444444\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\" style=\"color: #333333\"><span lang=\"EN-US\"><em>ACS Chem. Neurosci.<\/em> 13(1) 16-26 (2022)<span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\"><br \/>\n<\/span>DOI: 10.1021\/acschemneuro.1c00441 <\/span><\/span><\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2022 (\u8457\u66f8\u7b49)<\/h2>\n<ol>\n<li><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><br \/>\n<\/span><\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u653e\u5c04\u6027\u533b\u85ac\u54c1\u958b\u767a\u7814\u7a76\u3078\u306e\u62db\u5f85\u3000\u7b2c\uff14\u7ae0\u3000\u8133\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0<\/span><\/span><\/span><\/span><\/span><br \/>\n\u516c\u76ca\u793e\u56e3\u6cd5\u4eba\u3000\u65e5\u672c\u30a2\u30a4\u30bd\u30c8\u30fc\u30d7\u5354\u4f1a\u7b2c\uff12\u671f\u7406\u5de5\u30fb\u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u90e8\u4f1aRI\u5229\u7528\u63a8\u9032\u5c02\u9580\u59d4\u54e1\u4f1a<br \/>\n\u5275\u85ac\u7814\u7a76\u30ec\u30d3\u30e5\u30fc\u4f5c\u6210\u30ef\u30fc\u30ad\u30f3\u30b0\u30b0\u30eb\u30fc\u30d7<\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<h2>2022 (\u5b66\u4f1a\u767a\u8868)<\/h2>\n<ol>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">Hiroyuki Watanabe, Miho Ikawa, Masahiro Ono<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">Synthesis and evaluation of radioiodinated benzothiazole and benzoxazole derivatives for detection of myelin in multiple sclerosis<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">13th Congress of the World Federation of Nuclear Medicine and Biology<\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08Kyoto, Japan) \u00a0September 7-11, 2022<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c3e\u4e0a \u907c\u592a\u90ce, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u30aa\u30fc\u30b8\u30a7\u6cbb\u7642\u304a\u3088\u3073\u5149\u7dda\u529b\u5b66\u7642\u6cd5\u304c\u53ef\u80fd\u306aBODIPY\u7d50\u5408\u30d8\u30ad\u30b9\u30c8\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c5\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5206\u79d1\u4f1a \u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u7814\u7a76\u4f1a\/<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c21<\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u56de\u653e\u5c04\u6027\u533b\u85ac\u54c1\u30fb\u753b\u50cf\u8a3a\u65ad\u85ac\u7814\u7a76\u4f1a<\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u798f\u4e95)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2022\u5e749\u670817\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u571f\u6a4b \u660c\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u751a\u7530 \u6d38\u5e0c, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"s1\" style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u76f4\u9396\u578b\u4e09\u5b98\u80fd\u6027\u30ad\u30ec\u30fc\u30c8\u69cb\u9020\u3092\u57fa\u76e4\u3068\u3057\u305f\u65b0\u898f<sup>111<\/sup>In\u6a19\u8b58PSMA\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a<\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c5\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5206\u79d1\u4f1a \u653e\u5c04\u6027\u85ac\u54c1\u79d1\u5b66\u7814\u7a76\u4f1a\/<\/span><\/span><\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u7b2c21<\/span><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\">\u56de\u653e\u5c04\u6027\u533b\u85ac\u54c1\u30fb\u753b\u50cf\u8a3a\u65ad\u85ac\u7814\u7a76\u4f1a<\/span><\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">\uff08\u798f\u4e95)\u00a0\u00a0<\/span><span style=\"font-size: 14px;line-height: 1.3;text-indent: 1em\">2022\u5e749\u670817\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px\">\u77f3\u5742 \u512a\u8863, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><br \/>\n<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\">\u30aa\u30ec\u30ad\u30b7\u30f31\u53d7\u5bb9\u4f53\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898f<sup>18<\/sup>F\u6a19\u8b58\u30d9\u30f3\u30be\u30d5\u30e9\u30f3\u8a98\u5c0e\u4f53\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><\/span><\/span><\/span><\/span><br \/>\n<span style=\"color: #333333\">\u7b2c19\u56de\u6b21\u4e16\u4ee3\u3092\u62c5\u3046\u82e5\u624b\u306e\u305f\u3081\u306e\u30d5\u30a3\u30b8\u30ab\u30eb\u30fb\u30d5\u30a1\u30fc\u30de\u30d5\u30a9\u30fc\u30e9\u30e0 (\u6771\u4eac(\u30aa\u30f3\u30e9\u30a4\u30f3))\u00a0<span class=\"Apple-style-span\"><span class=\"Apple-style-span\">2022\u5e749\u670812\u65e5, 13\u65e5<\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">\u30a2\u30df\u30ed\u30a4\u30c9\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5264\u306e\u958b\u767a\u306b\u304a\u3051\u308b\u85ac\u5b66\u7684\u8ca2\u732e (\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0)<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c42\u56de\u65e5\u672c\u6838\u533b\u5b66\u6280\u8853\u5b66\u4f1a\u7dcf\u4f1a\u5b66\u8853\u5927\u4f1a\uff08\u4eac\u90fd\uff09 2022\u5e749\u67089\u65e5\u301c11\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u4e2d\u5cf6 \u4e00\u78e8, \u98ef\u570b \u614e\u5e73, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">\u30e9\u30b8\u30aa\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u7528\u30d7\u30e9\u30c3\u30c8\u30d5\u30a9\u30fc\u30e0ADA\u306e\u4e2d\u5206\u5b50\u30ea\u30ac\u30f3\u30c9\u306b\u5bfe\u3059\u308b\u5fdc\u7528\u6027\u306e\u8a55\u4fa1<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c62\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff09 2022\u5e749\u67089\u65e5\u301c11\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em\">\u6e21\u908a \u88d5\u4e4b, \u4e95\u51fa \u5353\u5fd7, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;line-height: inherit;text-indent: 1em\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span lang=\"EN-US\"><span style=\"font-size: 14px\"><span style=\"font-size: 14px;text-indent: 1em\">\u30aa\u30ec\u30ad\u30b7\u30f32\u53d7\u5bb9\u4f53\u3092\u6a19\u7684\u3068\u3057\u305f\u30c8\u30ea\u30a2\u30be\u30fc\u30eb-\u30d4\u30ed\u30ea\u30b8\u30f3\u985e\u7e01\u4f53\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em\">\u7b2c62\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u5b66\u8853\u7dcf\u4f1a\uff08\u4eac\u90fd\uff09 2022\u5e749\u67089\u65e5\u301c11\u65e5<\/span><\/span><\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u75c5\u614b\u6a5f\u80fd\u5206\u6790\u306e\u305f\u3081\u306e\u65b0\u898f\u653e\u5c04\u6027\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a\u7814\u7a76 (\u30b7\u30f3\u30dd\u30b8\u30a6\u30e0)<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c16\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a (\u4eac\u90fd) 2022\u5e745\u670826\u65e5, 27\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u6e21\u908a \u88d5\u4e4b, \u5cb8\u672c \u5cfb\u660e, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u30a2\u30df\u30ed\u30a4\u30c9-\u03b2\u30aa\u30ea\u30b4\u30de\u30fc\u3092\u6a19\u7684\u3068\u3057\u305f\u86cd\u5149\u30d7\u30ed\u30fc\u30d6\u3068\u3057\u3066\u306e BODIPY \u8a98\u5c0e\u4f53\u306e\u8a55\u4fa1<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c16\u56de\u65e5\u672c\u5206\u5b50\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u5b66\u4f1a (\u4eac\u90fd) 2022\u5e745\u670826\u65e5, 27\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">PET\u691c\u67fb\u85ac\u306e\u88fd\u9020\u30fb\u7ba1\u7406 (PET\u7814\u4fee\u30bb\u30df\u30ca\u30fc)<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u7b2c22\u56de\u65e5\u672c\u6838\u533b\u5b66\u4f1a\u6625\u5b63\u5927\u4f1a (\u30aa\u30f3\u30e9\u30a4\u30f3) 2022\u5e745\u67087\u65e5\u301c6\u67081\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u571f\u6a4b \u660c\u5e73, \u98ef\u570b \u614e\u5e73, \u4e2d\u5cf6 \u4e00\u78e8, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u816b\u760d\u96c6\u7a4d\u6027\u306e\u5411\u4e0a\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898fPSMA\u6a19\u7684\u30e9\u30b8\u30aa\u30bb\u30e9\u30ce\u30b9\u30c6\u30a3\u30af\u30b9\u85ac\u5264\u306e\u958b\u767a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c142\u5e74\u4f1a (\u540d\u53e4\u5c4b(\u30aa\u30f3\u30e9\u30a4\u30f3)) 2022\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u9577\u5d8b \u6d69\u592a\u6717, \u6e21\u908a \u88d5\u4e4b, \u8c9d\u51fa \u7fd4, \u98ef\u570b \u614e\u5e73, \u9577\u8c37\u5ddd \u6210\u4eba, \u4f0a\u6771 \u606d\u5b50, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u03b1\u30b7\u30cc\u30af\u30ec\u30a4\u30f3\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a\u3092\u76ee\u7684\u3068\u3057\u305f\u653e\u5c04\u6027\u30d5\u30c3\u7d20\u6a19\u8b58\u30ab\u30eb\u30b3\u30f3\u985e\u7e01\u4f53\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c142\u5e74\u4f1a (\u540d\u53e4\u5c4b(\u30aa\u30f3\u30e9\u30a4\u30f3)) 2022\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u4e95\u5ddd \u5b9f\u7a42, \u6e21\u908a \u88d5\u4e4b, \u98ef\u570b \u614e\u5e73, \u62b1 \u5c06\u53f2, \u767d\u5ddd \u4e45\u5fd7, \u91d1\u5b50 \u5468\u53f8, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u591a\u767a\u6027\u786c\u5316\u75c7\u306e\u8a3a\u65ad\u3092\u76ee\u7684\u3068\u3057\u305f\u30df\u30a8\u30ea\u30f3\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a\uff1a\u653e\u5c04\u6027\u30e8\u30a6\u7d20\u6a19\u8b58\u82b3\u9999\u65cf\u30d8\u30c6\u30ed\u74b0\u5316\u5408\u7269\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c142\u5e74\u4f1a (\u540d\u53e4\u5c4b(\u30aa\u30f3\u30e9\u30a4\u30f3)) 2022\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u6570\u591a \u4f38\u7d00, \u98ef\u570b \u614e\u5e73, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u7642\u6cd5\u306e\u6cbb\u7642\u52b9\u679c\u4e88\u6e2c\u306b\u8cc7\u3059\u308b\u65b0\u898f\u30b0\u30e9\u30f3\u30b6\u30a4\u30e0B\u6a19\u7684<sup>111<\/sup>In\u6a19\u8b58\u30a4\u30e1\u30fc\u30b8\u30f3\u30b0\u30d7\u30ed\u30fc\u30d6\u306e\u5408\u6210\u3068\u8a55\u4fa1<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c142\u5e74\u4f1a (\u540d\u53e4\u5c4b(\u30aa\u30f3\u30e9\u30a4\u30f3)) 2022\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\"><span lang=\"EN-US\">\u5c0f\u539f \u5d69\u8cb4, \u98ef\u570b \u614e\u5e73, \u6e21\u908a \u88d5\u4e4b, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u30a4\u30f3\u30b9\u30ea\u30ce\u30fc\u30de\u306e\u6838\u533b\u5b66\u8a3a\u65ad\u3092\u76ee\u7684\u3068\u3057\u305f\u65b0\u898f\u30a2\u30eb\u30d6\u30df\u30f3\u30d0\u30a4\u30f3\u30c0\u30fc\u7d50\u5408\u578b\u30b0\u30eb\u30ab\u30b4\u30f3\u69d8\u30da\u30d7\u30c1\u30c9-1\u53d7\u5bb9\u4f53\u6a19\u7684\u30d7\u30ed\u30fc\u30d6\u306e\u958b\u767a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c142\u5e74\u4f1a (\u540d\u53e4\u5c4b(\u30aa\u30f3\u30e9\u30a4\u30f3)) 2022\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><\/li>\n<li><span style=\"color: #333333\"><span class=\"Apple-style-span\"><span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u5c3e\u4e0a \u907c\u592a\u90ce, \u6e21\u908a \u88d5\u4e4b, \u98ef\u570b \u614e\u5e73, \u5c0f\u91ce \u6b63\u535a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n<span style=\"font-size: 14px;text-indent: 1em;line-height: 1.3\"><span style=\"font-size: 14px;text-indent: 1em\">\u30aa\u30fc\u30b8\u30a7\u6cbb\u7642\u3092\u76ee\u7684\u3068\u3057\u305f\u653e\u5c04\u6027\u30e8\u30a6\u7d20BODIPY\u7d50\u5408\u30d8\u30ad\u30b9\u30c8\u306e\u958b\u767a<\/span><\/span><\/span><span class=\"Apple-style-span\"><br \/>\n\u65e5\u672c\u85ac\u5b66\u4f1a \u7b2c142\u5e74\u4f1a (\u540d\u53e4\u5c4b(\u30aa\u30f3\u30e9\u30a4\u30f3)) 2022\u5e743\u670825\u65e5\u301c28\u65e5<\/span><\/span><span style=\"color: #333333\"><span class=\"Apple-style-span\"><br \/>\n<\/span><span class=\"Apple-style-span\"><br \/>\n<\/span><\/span><\/li>\n<\/ol>\n<p class=\"pagetop\"><a href=\"#header\" class=\"liinternal\">\u30da\u30fc\u30b8\u306e\u5148\u982d\u3078\u623b\u308b<\/a><\/p>\n<p class=\"pagetop\">\n","protected":false},"excerpt":{"rendered":"<p>2026 (\u8ad6\u6587) Akiba H, Nakashima K, Ichinose T, Watanabe H, Ono M Influence of the binding valency of anti-HER2 bi [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-363","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages\/363","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/comments?post=363"}],"version-history":[{"count":5,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages\/363\/revisions"}],"predecessor-version":[{"id":3454,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages\/363\/revisions\/3454"}],"wp:attachment":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/media?parent=363"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}