{"id":473,"date":"2013-09-12T13:39:57","date_gmt":"2013-09-12T04:39:57","guid":{"rendered":"http:\/\/www.keyton-co.jp\/kpharm\/byotai\/?page_id=473"},"modified":"2014-10-29T13:12:18","modified_gmt":"2014-10-29T04:12:18","slug":"%e8%bb%a2%e7%a7%bb%e6%80%a7%e9%aa%a8%e8%85%ab%e7%98%8d%e7%96%bc%e7%97%9b%e7%b7%a9%e5%92%8c%e7%94%a8%e6%94%be%e5%b0%84%e6%80%a7%e8%96%ac%e5%89%a4%e3%81%ae%e9%96%8b%e7%99%ba","status":"publish","type":"page","link":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/theme-list\/history\/%e8%bb%a2%e7%a7%bb%e6%80%a7%e9%aa%a8%e8%85%ab%e7%98%8d%e7%96%bc%e7%97%9b%e7%b7%a9%e5%92%8c%e7%94%a8%e6%94%be%e5%b0%84%e6%80%a7%e8%96%ac%e5%89%a4%e3%81%ae%e9%96%8b%e7%99%ba\/","title":{"rendered":"\u8ee2\u79fb\u6027\u9aa8\u816b\u760d\u75bc\u75db\u7de9\u548c\u7528\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a"},"content":{"rendered":"<h2>\u8ee2\u79fb\u6027\u9aa8\u816b\u760d\u75bc\u75db\u7de9\u548c\u7528\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a<\/h2>\n<p>\u8ee2\u79fb\u6027\u9aa8\u816b\u760d\u306e\u5185\u7528\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u76ee\u6307\u3057\u3001\u7d30\u80de\u6bba\u50b7\u6027\u306e\u9ad8\u30a8\u30cd\u30eb\u30ae\u30fc\u03b2<sup>&#8211;<\/sup>\u7dda\u3092\u653e\u51fa\u3059\u308b<sup>186<\/sup>Re\u306eMAG3\u932f\u4f53\u3068\u9aa8\u89aa\u548c\u6027\u3092\u6709\u3059\u308b\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u5206\u5b50\uff1aHBP\u3092\u7d50\u5408\u3055\u305b\u305f\u5316\u5408\u7269\u3001<sup>186<\/sup>Re-MAG3-HBP\u3092\u8a2d\u8a08\u30fb\u5408\u6210\u3057\u305f\u3002<\/p>\n<p>MRMT-1\u30e9\u30c3\u30c8\u4e73\u764c\u7d30\u80de\u3092\u811b\u9aa8\u306b\u63a5\u7a2e\u3057\u305f\u9aa8\u816b\u760d\u30e2\u30c7\u30eb\u52d5\u7269\u306b<sup>186<\/sup>Re-MAG3-HBP\u3092\u6295\u4e0e\u3057\u305f\u7d50\u679c\u3001SPECT\u64ae\u50cf\u306b\u304a\u3044\u3066\u816b\u760d\u79fb\u690d\u5468\u8fba\u90e8\u3078\u306e\u9ad8\u3044\u653e\u5c04\u80fd\u96c6\u7a4d\u3092\u8a8d\u3081\u305f\u3002\u3053\u308c\u306fCT\u304a\u3088\u3073\u7d44\u7e54\u5b66\u7684\u691c\u8a0e\u304b\u3089\u78ba\u8a8d\u3057\u305f\u3001\u9aa8\u5bc6\u5ea6\u306e\u6e1b\u5c11\u3068\u4e0d\u5747\u8cea\u306a\u9aa8\u5f62\u6210\u3001\u9020\u9aa8\u6d3b\u6027\u304c\u4ea2\u9032\u3057\u3066\u3044\u308b\u90e8\u4f4d\u3068\u4e00\u81f4\u3057\u3001\u672c\u85ac\u7269\u304c\u5185\u7528\u653e\u5c04\u7dda\u6cbb\u7642\u306b\u9069\u3057\u305f\u4f53\u5185\u52d5\u614b\u3092\u793a\u3059\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u305f\u3002\u3055\u3089\u306b\u3001\u7d4c\u6642\u7684\u306b\u816b\u760d\u4f53\u7a4d\u306e\u6e2c\u5b9a\u3068\u75bc\u75db\u691c\u5b9a\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001\u975e\u51e6\u7f6e\u7fa4\u3068\u6bd4\u8f03\u3057\u3066\u6709\u610f\u306a\u816b\u760d\u5897\u6b96\u6291\u5236\u52b9\u679c\u304a\u3088\u3073\u75bc\u75db\u7de9\u548c\u52b9\u679c\u3092\u8a8d\u3081\u305f\u3002\u4ee5\u4e0a\u306e\u7d50\u679c\u304b\u3089\u3001\u4e8c\u5b98\u80fd\u6027\u653e\u5c04\u6027\u85ac\u5264\u306e\u6982\u5ff5\u306b\u57fa\u3065\u3044\u3066\u65b0\u305f\u306b\u4f5c\u88fd\u3057\u305f<sup>186<\/sup>Re-MAG3-HBP\u306f\u3001\u8ee2\u79fb\u6027\u9aa8\u816b\u760d\u75bc\u75db\u7de9\u548c\u85ac\u5264\u3068\u3057\u3066\u6709\u7528\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u793a\u3055\u308c\u305f\u3002<\/p>\n<div id=\"attachment_252\" style=\"width: 727px\" class=\"wp-caption alignnone\"><a href=\"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-content\/blogs.dir\/2\/files\/2013\/06\/MAG3-HBP2.jpg\" class=\"liimagelink\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-252\" class=\" wp-image-252 \" src=\"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-content\/blogs.dir\/2\/files\/2013\/06\/MAG3-HBP2.jpg\" alt=\"MAG3-HBP2\" width=\"717\" height=\"477\" srcset=\"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/files\/2013\/06\/MAG3-HBP2.jpg 1080w, https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/files\/2013\/06\/MAG3-HBP2-300x200.jpg 300w, https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/files\/2013\/06\/MAG3-HBP2-1024x682.jpg 1024w\" sizes=\"auto, (max-width: 717px) 100vw, 717px\" \/><\/a><p id=\"caption-attachment-252\" class=\"wp-caption-text\">\u30af\u30ea\u30c3\u30af\u3059\u308b\u3068\u62e1\u5927\u8868\u793a\u3057\u307e\u3059\u3002<\/p><\/div>\n<h3>\u4e3b\u8981\u8ad6\u6587<\/h3>\n<ul>\n<li>Therapeutic effects of a <sup>186<\/sup>Re-complex-conjugated bisphosphonate for the palliation of metastatic bone pain in an animal model.<br \/>\nJ Nucl Med. 2007; 48(1): 122-127.<\/li>\n<li>Rhemium-186-monoaminemonoamidedithiol-conjugated bisphosphonate derivatives for bone pain palliation.<br \/>\nNucl Med Biol. 2006; 33(4): 513-520.<\/li>\n<li>Development of a rhenium-186-labeled MAG3-conjugated bisphosphonate for the palliation of metastatic bone pain based on the concept of bifunctional radiopharmaceuticals.<br \/>\nBioconjugate Chem. 2005; 16: 751-757.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u8ee2\u79fb\u6027\u9aa8\u816b\u760d\u75bc\u75db\u7de9\u548c\u7528\u653e\u5c04\u6027\u85ac\u5264\u306e\u958b\u767a \u8ee2\u79fb\u6027\u9aa8\u816b\u760d\u306e\u5185\u7528\u653e\u5c04\u7dda\u6cbb\u7642\u3092\u76ee\u6307\u3057\u3001\u7d30\u80de\u6bba\u50b7\u6027\u306e\u9ad8\u30a8\u30cd\u30eb\u30ae\u30fc\u03b2&#8211;\u7dda\u3092\u653e\u51fa\u3059\u308b186Re\u306eMAG3\u932f\u4f53\u3068\u9aa8\u89aa\u548c\u6027\u3092\u6709\u3059\u308b\u30d3\u30b9\u30db\u30b9\u30db\u30cd\u30fc\u30c8\u5206\u5b50\uff1aHBP\u3092\u7d50\u5408\u3055\u305b\u305f\u5316\u5408\u7269\u3001 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":467,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-473","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages\/473","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/comments?post=473"}],"version-history":[{"count":3,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages\/473\/revisions"}],"predecessor-version":[{"id":1599,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages\/473\/revisions\/1599"}],"up":[{"embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/pages\/467"}],"wp:attachment":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/byotai\/wp-json\/wp\/v2\/media?parent=473"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}