{"id":30148,"date":"2023-09-06T10:51:32","date_gmt":"2023-09-06T01:51:32","guid":{"rendered":"https:\/\/www.pharm.kyoto-u.ac.jp\/?p=30148"},"modified":"2026-04-17T11:12:46","modified_gmt":"2026-04-17T02:12:46","slug":"arrival-greeting-2023-6","status":"publish","type":"post","link":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/blog\/2023\/09\/06\/arrival-greeting-2023-6\/","title":{"rendered":"\u9ad9\u5c71\u52a9\u6559\u304c\u7740\u4efb\u3055\u308c\u307e\u3057\u305f\uff08\u85ac\u54c1\u5408\u6210\u5316\u5b66\u5206\u91ce\uff09"},"content":{"rendered":"

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\n\u79c1\u306e\u5c02\u9580\u306f\u6709\u6a5f\u5316\u5b66\u3067\u3059\u3002\u5275\u85ac\u5316\u5b66\u7814\u7a76\u3092\u4e2d\u5fc3\u306b\u53cd\u5fdc\u958b\u767a\u304b\u3089\u5408\u6210\u7814\u7a76\u3001\u6d3b\u6027\u8a55\u4fa1\u307e\u3067\u5e45\u5e83\u304f\u7814\u7a76\u3057\u3066\u53c2\u308a\u307e\u3057\u305f\u3002
\n\u672c\u5b66\u3067\u306f\u3001\u533b\u85ac\u54c1\u958b\u767a\u306b\u5fdc\u7528\u53ef\u80fd\u306a\u65b0\u53cd\u5fdc\u3092\u958b\u767a\u3059\u308b\u3053\u3068\u3067\u3001\u5275\u85ac\u306e\u6280\u8853\u5411\u4e0a\u306b\u8ca2\u732e\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002\u5316\u5b66\u306b\u3082\u5206\u5b50\u751f\u7269\u5b66\u306b\u3082\u5bc4\u4e0e\u3059\u308b\u3088\u3046\u306a\u7814\u7a76\u3092\u884c\u3046\u3053\u3068\u304c\u3001\u79c1\u306e\u76ee\u6a19\u3067\u3059\u3002
\n\u4eac\u90fd\u5927\u5b66\u85ac\u5b66\u7814\u7a76\u79d1\u306f\u3001\u69d8\u3005\u306a\u5c02\u9580\u5bb6\u304c\u304a\u308a\u3001\u5171\u540c\u7814\u7a76\u3082\u76db\u3093\u3067\u3042\u308b\u3068\u805e\u304d\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u5927\u5b66\u306e\u96f0\u56f2\u6c17\u3084\u7279\u8272\u304c\u3001\u79c1\u306e\u4eca\u307e\u3067\u7d4c\u9a13\u3057\u3066\u304d\u305f\u5834\u6240\u3068\u306f\u7570\u306a\u308b\u3088\u3046\u306b\u611f\u3058\u3066\u3044\u307e\u3059\u3002\u5b66\u751f\u3084\u4ed6\u306e\u5148\u751f\u65b9\u306e\u8003\u3048\u306b\u89e6\u308c\u306a\u304c\u3089\u3001\u5171\u306b\u7814\u7a76\u3067\u304d\u308b\u3053\u3068\u304c\u5927\u5909\u697d\u3057\u307f\u3067\u3059\u3002\u3088\u3044\u7814\u7a76\u304c\u3067\u304d\u308b\u3088\u3046\u7cbe\u4e00\u676f\u52aa\u3081\u307e\u3059\u306e\u3067\u3001\u3069\u3046\u305e\u3088\u308d\u3057\u304f\u304a\u9858\u3044\u3044\u305f\u3057\u307e\u3059\u3002<\/p>\n

 <\/p>\n

\u4e3b\u306a\u696d\u7e3e<\/h4>\n
    \n
  1. Kohyama, A<\/u>.; Shiuchi, A.; Zhou, Y.; Tanioka, M.; Sugimoto, K.; Sakurai, H.; Matsuya, Y.
    \nControllable conformation and reactivity of bicyclic \u03b1-methylene cyclopentanones and their NF-\u03baB pathway inhibitory activity
    \nOrg. Biomol. Chem<\/span>. 21, 4656\uff0d4660, 2023<\/strong><\/li>\n<\/ol>\n
      \n
    1. Kohyama, A<\/u>.; Kim, M. J.; Yokoyama, R.; Sun, S.; Omar, A. M.; Phan, N. D.; Meselhy, M. R.; Tsuge, K.; Awale, S.; Matsuya, Y.
      \nStructure-Activity Relationship and Mechanistic Study on Gugglesterone derivatives; Discovery of New Anti-pancreatic Cancer Candidate
      \nBioorg. Med. Chem<\/span>. 54, 116563\uff0d116573, 2022<\/strong><\/li>\n<\/ol>\n
        \n
      1. Kohyama, A.<\/u>; Koresawa, E.; Tsuge, K.; Matsuya, Y.
        \nFacile o<\/span><\/strong>-Quinodimethane Formation from Benzocyclobutenes Triggered by Staudinger Reaction at Ambient Temperature
        \nChem. Commun.<\/span> 55, 6205\uff0d6208, 2019<\/strong><\/li>\n<\/ol>\n
          \n
        1. Kohyama, A.<\/u>; Fukuda, M.; Sugiyama, S.; Yamakoshi, H.; Kanoh, N.; Ishioka, C.; Shibata, H.; Iwabuchi, Y.
          \nReversibility of thia-Michael reaction of the cytotoxic C5-curcuminoid and structure-activity relationship of the bis-thiol-adducts thereof
          \nOrg. Biomol. Chem. <\/span>14, 10683\uff0d10687, 2016<\/strong><\/li>\n<\/ol>\n
            \n
          1. Kohyama, A.<\/u>; Kanoh, N.; Kwon, E.; Iwabuchi, Y.
            \nAn enantiocontrolled entry to the tricyclic polar segment of (+)-fusarisetin A
            \nTetrahedron Lett. <\/span>57, 517\uff0d519, 2016<\/strong><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

            \u7686\u3055\u307e\u3001\u306f\u3058\u3081\u307e\u3057\u3066\u30022023\u5e749\u67081\u65e5\u3088\u308a\u85ac\u54c1\u5408\u6210\u5316\u5b66\u5206\u91ce\u306b\u52a9\u6559\u3068\u3057\u3066\u7740\u4efb\u3044\u305f\u3057\u307e\u3057\u305f\u9ad9\u5c71\u4e9c\u7d00\u3067\u3059\u3002\u79c1\u306f\u30012016\u5e743\u6708\u306b\u6771\u5317\u5927\u5b66\u85ac\u5b66\u7814\u7a76\u79d1 \u5ca9\u6e15\u6559\u6388\u306e\u4e0b\u3001\u535a\u58eb\u53f7\u3092\u53d6\u5f97\u3057\u307e\u3057\u305f\u3002\u305d\u306e\u5f8c\u3001\u5bcc\u5c71\u5927\u5b66\u85ac\u5b66\u90e8\uff085\u5e74\u9593\uff09\u3001\u6771\u5317\u5927 […]<\/p>\n","protected":false},"author":12,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"_bbp_topic_count":0,"_bbp_reply_count":0,"_bbp_total_topic_count":0,"_bbp_total_reply_count":0,"_bbp_voice_count":0,"_bbp_anonymous_reply_count":0,"_bbp_topic_count_hidden":0,"_bbp_reply_count_hidden":0,"_bbp_forum_subforum_count":0,"_crdt_document":"","_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2}},"categories":[5],"tags":[],"class_list":["post-30148","post","type-post","status-publish","format-standard","hentry","category-info"],"acf":[],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/posts\/30148","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/comments?post=30148"}],"version-history":[{"count":2,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/posts\/30148\/revisions"}],"predecessor-version":[{"id":30152,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/posts\/30148\/revisions\/30152"}],"wp:attachment":[{"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/media?parent=30148"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/categories?post=30148"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pharm.kyoto-u.ac.jp\/en\/wp-json\/wp\/v2\/tags?post=30148"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}