{"id":218,"date":"2025-04-25T13:12:58","date_gmt":"2025-04-25T04:12:58","guid":{"rendered":"https:\/\/www.pharm.kyoto-u.ac.jp\/souyaku?page_id=218"},"modified":"2025-10-27T11:03:17","modified_gmt":"2025-10-27T02:03:17","slug":"research","status":"publish","type":"page","link":"https:\/\/www.pharm.kyoto-u.ac.jp\/souyaku\/?page_id=218","title":{"rendered":"Research"},"content":{"rendered":"\n<div>&nbsp;<\/div>\n\n\n\n<div>&nbsp;<\/div>\n\n\n\n<div>\u00a0<\/div>\n\n\n\n<div>\u00a0<\/div>\n\n\n\n<div><span style=\"font-family: tahoma, arial, helvetica, sans-serif\"><span style=\"font-size: 12pt\">\u751f\u547d\u73fe\u8c61\u306f\u3001\u6570\u591a\u304f\u306e\u6709\u6a5f\u5316\u5408\u7269\u306e\u53cd\u5fdc\u3084\u5e73\u8861\u306b\u3088\u3063\u3066\u6210\u308a\u7acb\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/span><span style=\"font-size: 12pt\"><span style=\"font-size: 12pt\"><span style=\"font-family: tahoma, arial, helvetica, sans-serif\">\u75c5\u6c17\u3068\u306f\u751f\u614b\u306e\u6052\u5e38\u6027\uff08\u30db\u30e1\u30aa\u30b9\u30bf\u30b7\u30b9\uff09\u306b\u4f55\u3089\u304b\u306e\u7570\u5e38\u304c\u751f\u3058\u3066\u3044\u308b\u72b6\u614b\u3067\u3059\u3002 <\/span><span style=\"font-family: tahoma, arial, helvetica, sans-serif\">\u75c5\u6c17\u306e\u6cbb\u7642\u306b\u4f7f\u308f\u308c\u308b\u533b\u85ac\u54c1\u3082\u307b\u3068\u3093\u3069\u306e\u5834\u5408\u6709\u6a5f\u5316\u5408\u7269\u3067\u3042\u308b\u305f\u3081\u3001\u533b\u85ac\u54c1\u3092\u5275\u88fd\u3057\u305f\u308a\u9069\u5207\u306b\u4f7f\u7528\u3057\u305f\u308a\u3059\u308b\u305f\u3081\u306b\u306f\u3001\u6709\u6a5f\u5316\u5b66\u3092\u6df1\u304f\u7406\u89e3\u3057\u306a\u304f\u3066\u306f\u306a\u308a\u307e\u305b\u3093\u3002\u5f53\u5206\u91ce\u3067\u306f\u3001\u6709\u6a5f\u5316\u5b66\u3092\u57fa\u76e4\u3068\u3057\u305f\u5275\u85ac\u3078\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u3057\u3066\u3001\u4ee5\u4e0b\u306e\u7814\u7a76\u3092\u63a8\u9032\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/span><\/span><\/div>\n\n\n\n<pre class=\"wp-block-preformatted\">&nbsp;<\/pre>\n\n\n\n<h2 class=\"wp-block-heading\"><span style=\"font-size: 14pt;color: #003366\"><span style=\"font-family: tahoma, arial, helvetica, sans-serif\">1)<span style=\"color: #003366\"> \u751f\u7269\u6d3b\u6027\u5316\u5408\u7269\u306e\u5408\u6210\u3068\u5275\u85ac\u5c55\u958b<\/span><\/span><\/span><\/h2>\n\n\n\n<div><span style=\"font-family: tahoma, arial, helvetica, sans-serif;font-size: 12pt\">\u6700\u8fd1\u3001\u7c21\u5358\u306b\u5408\u6210\u3067\u304d\u308b\u4f4e\u5206\u5b50\u5316\u5408\u7269\u304b\u3089\u533b\u85ac\u54c1\u3092\u5275\u308b\u3053\u3068\u304c\u96e3\u3057\u304f\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u7406\u7531\u306e\uff11\u3064\u306f\u3001\u76db\u3093\u306b\u884c\u308f\u308c\u3066\u304d\u305f\u7db2\u7f85\u7684\u5316\u5408\u7269\u5408\u6210\u3068\u9ad8\u901f\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u306b\u3088\u3063\u3066\u3001\u5408\u6210\u3057\u3084\u3059\u3044\u5316\u5408\u7269\u3092\u7528\u3044\u305f\u5275\u85ac\u7814\u7a76\u304c\u3084\u308a\u5c3d\u304f\u3055\u308c\u3064\u3064\u3042\u308b\u3053\u3068\u3067\u3059\u3002\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u3053\u3046\u3057\u305f\u73fe\u72b6\u3092\u6253\u7834\u3059\u308b\u305f\u3081\u306e\u53d6\u308a\u7d44\u307f\u3068\u3057\u3066\u3001\u8208\u5473\u6df1\u3044\u751f\u7269\u6d3b\u6027\u3092\u6709\u3057\u3001\u304b\u3064\u5408\u6210\u304c\u96e3\u3057\u3044\u69cb\u9020\u3092\u6709\u3059\u308b\u5929\u7136\u6709\u6a5f\u5316\u5408\u7269\u306e\u5408\u6210\u7814\u7a76\u3068\u5275\u85ac\u5c55\u958b\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u6700\u8fd1\u3067\u306f\u3001\u8907\u96d1\u306a\u74b0\u69cb\u9020\u3092\u6709\u3059\u308b\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\u3084\u5927\u74b0\u72b6\u30da\u30d7\u30c1\u30c9\u306e\u5408\u6210\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002<br \/><\/span><\/div>\n<pre>\u00a0<\/pre>\n<p>\u00a0<\/p>\n\n\n\n<div align=\"left\">\n<h2 align=\"left\"><span style=\"font-family: tahoma, arial, helvetica, sans-serif;font-size: 14pt;color: #003366\">2) \u8907\u96d1\u306a\u5316\u5b66\u69cb\u9020\u3092\u4e00\u6319\u306b\u69cb\u7bc9\u3059\u308b\u305f\u3081\u306e\u65b0\u53cd\u5fdc\u306e\u958b\u767a<\/span><\/h2>\n<\/div>\n\n\n\n<div style=\"text-align: left\"><span style=\"font-family: tahoma, arial, helvetica, sans-serif;font-size: 12pt\">\u8208\u5473\u6df1\u3044\u751f\u7269\u6d3b\u6027\u3092\u6301\u3063\u3066\u3044\u308b\u5316\u5408\u7269\u3067\u3042\u3063\u3066\u3082\u3001\u69cb\u9020\u304c\u8907\u96d1\u3059\u304e\u308b\u3068\u5275\u85ac\u7814\u7a76\u306b\u7528\u3044\u308b\u3053\u3068\u304c\u56f0\u96e3\u3067\u3059\u3002\u3053\u308c\u306f\u3001\u69cb\u9020\u6d3b\u6027\u76f8\u95a2\u7814\u7a76\u306b\u304a\u3044\u3066\u95a2\u9023\u5316\u5408\u7269\u3092\u591a\u6570\u5408\u6210\u3057\u305f\u308a\u3001\u6d3b\u6027\u3084\u7269\u6027\u3092\u6539\u5584\u3059\u308b\u30d7\u30ed\u30bb\u30b9\u306b\u6642\u9593\u3084\u52b4\u529b\u304c\u304b\u304b\u308a\u3059\u304e\u308b\u304b\u3089\u3067\u3059\u3002\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u751f\u7269\u6d3b\u6027\u5316\u5408\u7269\u306b\u5171\u901a\u3057\u3066\u5b58\u5728\u3059\u308b\u8907\u96d1\u306a\u69cb\u9020\u3092\u3001\u4e00\u5ea6\u306e\u53cd\u5fdc\u3067\u52b9\u7387\u7684\u306b\u69cb\u7bc9\u3059\u308b\u65b0\u3057\u3044\u624b\u6cd5\u306e\u958b\u767a\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u6700\u8fd1\u3067\u306f\u3001\u539f\u5b50\u3092\u7121\u99c4\u9063\u3044\u3057\u306a\u3044\u53cd\u5fdc\u306b\u7740\u76ee\u3057\u3066\u3001\u91d1\u3084\u30d1\u30e9\u30b8\u30a6\u30e0\u306e\u3088\u3046\u306a\u9077\u79fb\u91d1\u5c5e\u89e6\u5a92\u3092\u7528\u3044\u305f\u6700\u5148\u7aef\u306e\u53cd\u5fdc\u958b\u767a\u7814\u7a76\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002\u3055\u3089\u306b\u3001\u958b\u767a\u3057\u305f\u53cd\u5fdc\u306e\u6709\u7528\u6027\u3092\u5b9f\u8a3c\u3059\u308b\u3079\u304f\u3001\u5275\u85ac\u7814\u7a76\u3084\u69cb\u9020\u6709\u6a5f\u7814\u7a76\u306b\u5fdc\u7528\u3082\u7cbe\u529b\u7684\u306b\u9032\u3081\u3066\u304a\u308a\u307e\u3059\u3002<br \/><\/span><\/div>\n<pre>\u00a0<\/pre>\n<p>\u00a0<\/p>\n\n\n\n<div class=\"font_area\" align=\"center\">\n<h2 align=\"left\"><span style=\"font-family: tahoma, arial, helvetica, sans-serif;color: #003366;font-size: 14pt\">3) \u86cb\u767d\u8cea\u5de5\u5b66\u30fb\u30d0\u30a4\u30aa\u30b3\u30f3\u30b8\u30e5\u30b2\u30fc\u30b7\u30e7\u30f3\u5316\u5b66\u306b\u3088\u308b\u6297\u4f53\u533b\u85ac\u54c1\u5019\u88dc\u306e\u9ad8\u6a5f\u80fd\u5316<\/span><\/h2>\n<\/div>\n\n\n\n<div style=\"text-align: left\"><span style=\"font-family: tahoma, arial, helvetica, sans-serif\">\u6297\u4f53\u533b\u85ac\u54c1\u306f\u4f4e\u5206\u5b50\u533b\u85ac\u54c1\u3068\u540c\u69d8\u306b\u3001\u6c4e\u7528\u3055\u308c\u308b\u5275\u85ac\u30e2\u30c0\u30ea\u30c6\u30a3\u3068\u306a\u308a\u307e\u3057\u305f\u3002\u305d\u306e\u4e00\u65b9\u3067\u30011)\u306b\u6319\u3052\u308b\u4f4e\u5206\u5b50\u5316\u5408\u7269\u306e\u8ab2\u984c\u3068\u540c\u69d8\u306b\u3001\u5358\u7d14\u306a\u6297\u4f53\u304c\u533b\u85ac\u54c1\u3068\u306a\u308b\u3088\u3046\u306a\u6a19\u7684\u306f\u6398\u308a\u3064\u304f\u3055\u308c\u3064\u3064\u3042\u308a\u307e\u3059\u3002\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u86cb\u767d\u8cea\u5de5\u5b66\u306e\u751f\u5316\u5b66\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u3068\u3001\u30b3\u30f3\u30b8\u30e5\u30b2\u30fc\u30c8\u5316\u5b66\u306e\u6709\u6a5f\u5316\u5b66\u7684\u30a2\u30d7\u30ed\u30fc\u30c1\u3092\u52b9\u7387\u7684\u306b\u7d44\u307f\u5408\u308f\u305b\u308b\u3053\u3068\u3067\u3001\u65b0\u3057\u3044\u6297\u4f53\u6539\u5909\u6280\u8853\u306e\u5275\u88fd\u7814\u7a76\u3092\u9032\u3081\u3066\u3044\u307e\u3059\u3002\u5f93\u6765\u3001\u6297\u4f53\u306e\u6709\u6a5f\u5316\u5b66\u7684\u6539\u5909\u306f\u3082\u3063\u3071\u3089\u6297\u4f53\u85ac\u7269\u8907\u5408\u4f53\uff08ADC\uff09\u306e\u3088\u3046\u306b\u3001\u6297\u4f53\u3092\u30c9\u30e9\u30c3\u30b0\u30c7\u30ea\u30d0\u30ea\u30fc\u306b\u5229\u7528\u3059\u308b\u3082\u306e\u3067\u3057\u305f\u304c\u3001\u6211\u3005\u306f\u6297\u4f53\u306e\u5206\u5b50\u8a8d\u8b58\u6a5f\u80fd\u305d\u306e\u3082\u306e\u306b\u4ecb\u5165\u3057\u3001\u307e\u305f\u3053\u308c\u3092\u65b0\u305f\u306a\u76ee\u7684\u306b\u5229\u7528\u3059\u308b\u305f\u3081\u306e\u6280\u8853\u3092\u958b\u767a\u3057\u3066\u3044\u307e\u3059\u3002\u57fa\u76e4\u6280\u8853\u958b\u767a\u3092\u901a\u3058\u3066\u5c06\u6765\u306e\u65b0\u6a5f\u5e8f\u6297\u4f53\u533b\u85ac\u54c1\u306e\u5275\u88fd\u3092\u76ee\u6307\u3059\u3068\u3068\u3082\u306b\u3001\u3053\u306e\u6280\u8853\u3092\u6d3b\u304b\u3057\u3066\u3001\u7523\u5b66\u306e\u6297\u4f53\u5275\u85ac\u652f\u63f4\u3092\u5b9f\u65bd\u3057\u3066\u3044\u307e\u3059\u3002<\/span><\/div>\n\n\n\n<div>\u00a0<\/div>\n\n\n\n<div><span style=\"font-family: tahoma, arial, helvetica, sans-serif\">\u672c\u7814\u7a76\u306f\u3001\u85ac\u5b66\u7814\u7a76\u79d1\u30fb<span style=\"color: #3366ff\"><a href=\"https:\/\/www.pharm.kyoto-u.ac.jp\/kunib\/biopharm\/index.html\" style=\"color: #3366ff\" class=\"liinternal\">\u30d0\u30a4\u30aa\u533b\u85ac\u54c1\u5316\u5b66\u5206\u91ce<\/a><\/span>\u3068\u9023\u643a\u3057\u3066\u5b9f\u65bd\u3057\u3066\u3044\u307e\u3059\u3002<br \/><\/span><\/div>\n<pre>\u00a0<\/pre>\n\n\n\n<div class=\"font_area\" align=\"center\">\n<h2 align=\"left\"><span style=\"font-family: tahoma, arial, helvetica, sans-serif;color: #003366;font-size: 14pt\">4)&nbsp;\u5316\u5408\u7269\u30e9\u30a4\u30d6\u30e9\u30ea\u30fc\u306e\u69cb\u7bc9\u3068\u305d\u308c\u3089\u3092\u6d3b\u7528\u3057\u305f\u6a5f\u80fd\u6027\u5206\u5b50\u306e\u63a2\u7d22<\/span><\/h2>\n<\/div>\n\n\n\n<div><span style=\"font-family: tahoma, arial, helvetica, sans-serif\">\u533b\u85ac\u54c1\u306e\u5019\u88dc\u5316\u5408\u7269\u3068\u306a\u308a\u5f97\u308b\u65b0\u3057\u3044\u751f\u7269\u6d3b\u6027\u5316\u5408\u7269\u3092\u63a2\u7d22\u3059\u308b\u3053\u3068\u306f\u3001\u533b\u85ac\u54c1\u958b\u767a\u306e\u91cd\u8981\u8ab2\u984c\u306e\u3072\u3068\u3064\u3067\u3059\u3002\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u9577\u5e74\u306b\u308f\u305f\u308a\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u5929\u7136\u6709\u6a5f\u5316\u5408\u7269\u3084\u30da\u30d7\u30c1\u30c9\u30db\u30eb\u30e2\u30f3\u3092\u306f\u3058\u3081\u3068\u3059\u308b\u751f\u4f53\u95a2\u9023\u5206\u5b50\u306a\u3069\u3001\u591a\u7a2e\u591a\u69d8\u306a\u6709\u6a5f\u5316\u5408\u7269\u3092\u5316\u5b66\u5408\u6210\u3057\u3066\u304d\u307e\u3057\u305f\u3002\u307e\u305f\u3001\u3053\u308c\u3089\u3092\u5408\u6210\u3059\u308b\u305f\u3081\u306e\u4e2d\u9593\u4f53\u30fb\u524d\u99c6\u4f53\u3092\u542b\u3081\u308b\u3068\u6570\u4e07\u691c\u4f53\u306b\u53ca\u3076\u5316\u5408\u7269\u306e\u30b9\u30c8\u30c3\u30af\u3092\u4fdd\u6709\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u3046\u3057\u305f\u5e02\u8ca9\u5316\u5408\u7269\u306b\u306a\u3044\u7279\u5fb4\u7684\u306a\u5316\u5b66\u69cb\u9020\u3092\u6709\u3059\u308b\u53ce\u96c6\u5316\u5408\u7269\u7fa4\u3092\u533b\u85ac\u54c1\u958b\u767a\u7814\u7a76\u306e\u30ea\u30bd\u30fc\u30b9\u3068\u3057\u3066\u6709\u52b9\u6d3b\u7528\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3001\u5316\u5408\u7269\u30e9\u30a4\u30d6\u30e9\u30ea\u30fc\u3092\u69cb\u7bc9\u3057\u3001\u5b66\u5185\u5916\u306e\u7814\u7a76\u6a5f\u95a2\u3068\u306e\u5171\u540c\u7814\u7a76\u306b\u3088\u308a\u3055\u307e\u3056\u307e\u306a\u30b9\u30af\u30ea\u30fc\u30cb\u30f3\u30b0\u3092\u884c\u3063\u3066\u3044\u307e\u3059\u3002<\/span><\/div>\n\n\n\n<pre class=\"wp-block-preformatted\"><\/pre>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; &nbsp; \u00a0 \u00a0 \u751f\u547d\u73fe\u8c61\u306f\u3001\u6570\u591a\u304f\u306e\u6709\u6a5f\u5316\u5408\u7269\u306e\u53cd\u5fdc\u3084\u5e73\u8861\u306b\u3088\u3063\u3066\u6210\u308a\u7acb\u3063\u3066\u3044\u307e\u3059\u3002\u75c5\u6c17\u3068\u306f\u751f\u614b\u306e\u6052\u5e38\u6027\uff08\u30db\u30e1\u30aa\u30b9\u30bf\u30b7\u30b9\uff09\u306b\u4f55\u3089\u304b\u306e\u7570\u5e38\u304c\u751f\u3058\u3066\u3044\u308b\u72b6\u614b\u3067\u3059\u3002 \u75c5\u6c17\u306e\u6cbb\u7642\u306b\u4f7f\u308f\u308c\u308b\u533b\u85ac\u54c1\u3082\u307b\u3068\u3093\u3069\u306e\u5834 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