[2025][2024][2023][2022][2021][2020][2019][2018][2017][2016][2015] [2014] [2013以前]

2025

  1. Takahara, A.; Nakatsu, T.; Hirata, K.; Hayashi, H.; Kawaji, K.; Aoki, K.; Inuki, S.; Ohno, H.; Kato, H.; Kodama, E.; Oishi, S.
    Elucidation of Postfusion Structures of the Measles Virus F Protein for the Structure-Based Design of Fusion Inhibitors.
    J. Med. Chem. 2025, 68, 3123–3133.
    DOI: 10.1021/acs.jmedchem.4c02337
  2. Akiba, H.; Ise, T.; Satoh, R.; Abe, Y.; Tsumoto, K.; Ohno, H.; Kamada, H.; Nagata, S.
    Generation of antagonistic biparatopic anti-CD30 antibody from an agonistic antibody by precise epitope determination and utilization of structural characteristics of CD30 molecule
    Antib. Ther. 2025, 8, 56–67.
    DOI: 10.1093/abt/tbaf002
  3. Suzuki, T.; Nojo, W.; Kawada, Y.; Sugiyama, S.; Ikeuchi, T.; Ishigaki, Y.; Ohno, H.
    Gold(I)-catalyzed Synthesis of Axially Chiral Indolo[2,3-c]carbazole Exhibiting Advanced Electrochromic Response.
    Asian J. Org. Chem. 2025, 14, e202400695.
    DOI: 10.1002/ajoc.202400695
  4. Watanabe, K.; Yamano, M.; Miyamoto, J.; Ohue-Kitano, R.; Masujima, Y.; Sasahara, D.; Mouri, Y.; Kono, N.; Inuki, S.; Osakada, F.; Nagaoka, K.; Aoki, J.; Sugiura, Y.; Ohno, H.; Kondoh, E.; Kimura, I.
    Maternal progesterone and adipose mPRε in pregnancy regulate the embryonic nutritional state.
    Cell Rep. 2025, 44, 115433.
    DOI: 10.1016/j.celrep.2025.115433
  5. Park, Y.; Matsumoto, S.; Ogata, K.; Ma, B.; Kanada, R.; Isaka, Y.; Arichi, N.; Liang, X.; Maki, R.; Kazasa, T.; Okuno, Y.; Ohno, H.; Ishihama, Y.; Toyoshima, F. Receptor-independent regulation of Gα13 by alpha-1-antitrypsin C-terminal peptides
    J. Biol. Chem. 2025, 301, 108136.
    DOI: 10.1016/j.jbc.2024.108136
  6. Shimizu, H.; Miyamoto, J.; Hisa, K.; Ohue-Kitano, R.; Takada, H.; Yamano, M.; Nishida, A.; Sasahara, D.; Masujima, Y.; Watanabe, K.; Nishikawa, S.; Takahashi, S.; Ikeda, T.; Nakajima, Y.; Yoshida, N.; Matsuzaki, C.; Kageyama, T.; Hayashi, I.; Matsuki, A.; Akashi, R.; Kitahama, S.; Ueyama, M.; Murakami, T.; Inuki, S.; Irie, J.; Satoh-Asahara, N.; Toju, H.; Mori, H.; Nakaoka, S.; Yamashita, T.; Toyoda, A.; Yamamoto, K.; Ohno, H.; Katayama, T.; Itoh, H.; Kimura, I.
    Sucrose-preferring Gut Microbes Prevent Host Obesity by Producing Exopolysaccharides.
    Nat. Commun. 2025, 16, 1145.
    DOI: 10.1038/s41467-025-56470-0
  7. Hasegawa, D.; Tsuji, A.; Greiner, L. C.; Arichi, N.; Inuki, S.; Ohno, H.
    Synthesis of Azocine-Fused Indoles via Gold(I)-Catalyzed Cyclization of Azido-alkynes.
    J. Org. Chem. 2025, 90, 925–930.
    DOI: 10.1021/acs.joc.4c02704
  8. Matsuoka, T.; Takasaki, R.; Akiba, H.; Ogata, K.; Hattori, A.; Arichi, N.; Kakeya, H.; Yamasaki, S.; Ishihama, Y.; Ohno, H.; Inuki, S.
    Visible light-mediated photocatalytic coupling between tetrazoles and carboxylic acids for biomolecule labelling.
    Chem. Commun. 2025, 61, 6320–6323.
    DOI: 10.1039/D4CC04452E

2024

  1. Takasaki, R.; Ito, E.; Nagae, M.; Takahashi, Y.; Matsuoka, T.; Yasue, W.; Arichi, N.; Ohno, H.; Yamasaki, S.; Inuki, S.
    Development of Ribityllumazine Analog as Mucosal-associated Invariant T Cell Ligand.
    J. Am. Chem. Soc. 2024, 146, 29964–29976.
    DOI: 10.1021/jacs.4c12997
  2. Nakamura, S.; Nishiwaki, K.; Tsuyuguchi, M.; Kinoshita, T.; Oishi, S.; Ohni. H.; Nakanishi, I.
    Compounds Designs of CK2α Inhibitors Derived from Virtual Screening Hit Compounds by Computational Chemistry with Crystallography.
    Chem. Pharm. Bull. 2024, 72, 776–780.
  3. Aoki, K.; Maeda, K.; Inuki, S.; Ohno, H.; Nonaka, M.; Oishi, S.
    Chemical Synthesis of Interleukin-6 for Mirror-Image Screening.
    Bioconjug. Chem. 2024, 35, 1190–1199.
    DOI: doi/10.1021/acs.bioconjchem.4c00204
  4. Hashimoto, N.; Taguchi, J.; Kasagi, T.; Arichi, N.; Inuki, S.; Ohno, H.
    Construction of the Akuammiline Alkaloid Core Structure via Stereoselective E-ring Formation.
    J. Org. Chem. 2024, 89, 10388–10392.
  5. Arichi, N.; Amano, T.; Wu, S.; Inuki, S.; Ohno, H.
    Synthesis of Sulfilimines via Visible-Light-Mediated Triplet Energy Transfer to Sulfonyl Azides.
    Chem. Eur. J. 2024, 30, e202401842.
    DOI: 10.1002/chem.202401842
  6. Iwamoto, N.; Kai, T.; Inuki, S.; Ohno, H.; Maeda, H.; Watanabe, H.; Maruyama, T.; Oishi, S.
    Mirror-Image Human Serum Albumin Domain III as a Tool for Analyzing Site II-Dependent Molecular Recognition.
    Bioconjug. Chem. 2024, 35, 816–825.
    DOI: 10.1021/acs.bioconjchem.4c00150
  7. Aoki, K.; Higashi, K.; Oda, S.; Manabe, A.; Maeda, K.; Morise, J.; Oka, S.; Inuki, S.; Ohno, H.; Oishi, S.; Nonaka, M.
    Engineering a Low-Immunogenic Mirror-Image VHH against Vascular Endothelial Growth Factor.
    ACS Chem. Biol. 2024, 19, 1194–1205.
    DOI: 10.1021/acschembio.4c00197

  8. Yoshida, Y.; Takeuchi, H.; Arichi, N.; Oishi, S.; Ohno, H.; Inuki, S.
    Approach to Spirocyclohexadienes via Visible Light-Mediated ipso-Cyclization of Amino Acid Derivatives with N-(2-Phenyl)benzoyl Groups.
    Asian J. Org. Chem. 2024, 13, e202400140.
    DOI: 10.1002/ajoc.202400140
  9. Inuki, S.; Miyamoto, J.; Hashimoto, N.; Shimizu, H.; Tabuchi, H.; Kawai, A.; Greiner, L. C.; Kimura, I.; Ohno, H.
    Structure-Activity Relationship Studies of Tetrahydroquinolone Derivatives as GPR41 Modulators.
    Bioorg. Med. Chem. Lett. 2024, 107, 129758.
    DOI: 10.1016/j.bmcl.2024.129758
  10. Aoki, K.; Tsuda, S.; Ogata, N.; Kataoka, M.; Sasaki, J.; Inuki, S.; Ohno, H.; Watashi, K.; Yoshiya, T.; Oishi, S.
    Synthetic Study of Full-length Hepatitis B Virus Core Protein and Its Capsid Formation.
    Org. Biomol. Chem. 2024, 22, 2218–2225.
    DOI: doi.org/10.1039/D3OB02099A
  11. Yamaguchi, A.; Obiya, N.; Arichi, N.; Oishi, S.; Ohno, H.; Inuki, S.
    Synthesis of Labionin and Avionin Precursors via Nitrogen-centred-radical-triggered 1,5-HAT Reaction of Tris Derivatives.
    Org. Biomol. Chem. 2024, 22, 2049–2055.
    DOI: 10.1039/D3OB02037A
  12. Iwamoto, N.; Sakaki, J.; Ohno, S.; Aoki, K.; Usui, Y.; Inuki, S.; Ohno, H.; Oishi, S.
    Synthetic Studies on the Extracellular Domain of the T Cell Immunoreceptor with Immunoglobulin and Immunoreceptor Tyrosine-Based Inhibitory Motif Domain (TIGIT) Using Trt-K10 Solubilizing Tags.
    Bioorg. Med. Chem. 2024, 99, 117585.
    DOI: 10.1016/j.bmc.2023.117585
  13. Ito, E.; Inuki, S.; Izumi, Y.; Takahashi, M.; Dambayashi, Y.; Ciacchi, L.; Awad, W.; Takeyama, A.; Shibata, K.; Mori, S.; Mak, J. Y. W.; Fairlie, D. P.; Bamba, T.; Ishikawa, E.; Nagae, M.; Rossjohn, J.; Yamasaki, S.
    Sulfated Bile Acid is a Host-derived Ligand for MAIT Cells.
    Sci. Immunol. 2024, 9, eade6924.
    DOI: 10.1126/sciimmunol.ade6924
  14. Ohno, H.; Arichi, N.; Inuki, S.
    Nonbiomimetic Total Synthesis of Polycyclic Alkaloids.
    Modern Natural Product Synthesis: Overcoming Difficulties, 1st ed; Springer, 2024.

2023

  1. Akiba, H.; Fujita, J.; Ise, T.; Nishiyama, K.; Miyata, T.; Kato, T.; Namba, K.; Ohno, H.; Kamada, H.; Nagata, S.; Tsumoto, K.
    Development of a 1:1-Binding Biparatopic anti-TNFR2 Antagonist by Reducing Signaling Activity through Epitope Selection.
    Commun. Biol. 2023, 6, 987.
    DOI: 10.1038/s42003-023-05326-8
  2. Hashimoto, N.; Taguchi, J.; Arichi, N.; Inuki, S.; Ohno, H.
    Gold(I)-Catalyzed Cascade Cyclization of Alkynyl Indoles for the Stereoselective Construction of the Quaternary Carbon Center of Akuammiline Alkaloids.
    J. Org. Chem. 2023, 88, 17306–17321.
    DOI: 10.1021/acs.joc.3c02142
  3. Aoki, K.; Manabe, A.; Kimura, H.; Katoh, Y.; Inuki, S.; Ohno, H.; Nonaka, M.; Oishi, S.
    Mirror-Image Single-Domain Antibody for a Novel Nonimmunogenic Drug Scaffold.
    Bioconjug. Chem. 2023, 34, 2055–2065.
    DOI: 10.1021/acs.bioconjchem.3c00372
  4. Iwamoto, N.; Sato, Y.; Manabe, A.; Inuki, S.; Ohno, H.; Nonaka, M.; Oishi, S.
    Design and Synthesis of Monobody Variants with Low Immunogenicity.
    ACS Med. Chem. Lett. 2023, 14, 1596–1601.
    DOI: 10.1021/acsmedchemlett.3c00342
  5. Matsuoka, T.; Hattori, A.; Oishi, S.; Araki, M.; Ma, B.; Fujii, T.; Arichi, N.; Okuno, Y.; Kakeya, H.; Yamasaki, S.; Ohno, H.; Inuki, S.
    Establishment of an MR1-Presentation Reporter Screening System and Identification of Phenylpropanoid Derivatives as MR1 Ligands.
    J. Med. Chem. 2023, 66, 12520–12535.
    DOI: 10.1021/acs.jmedchem.3c01122
  6. Oka, S.; Watanabe, M.; Ito, E.; Takeyama, A.; Matsuoka, T.; Takahashi, M.; Izumi, Y.; Arichi, N.; Ohno, H.; Yamasaki, S.; Inuki, S.
    Archaeal Glycerolipids Are Recognized by C-type Lectin Receptor Mincle.
    J. Am. Chem. Soc. 2023, 145, 18538–18548.
    DOI: 10.1021/jacs.3c05473
  7. Suzuki, R.; Mattos, D. R.; Kitamura, T.; Tsujioka, R.; Kobayashi, K.; Inuki, S.; Ohno, H.; Ishmael, J. E.; McPhail, K. L.; Oishi, S.
    Design of Synthetic Surrogates for the Macrolactone Linker Motif in Coibamide A.
    ACS Med. Chem. Lett. 2023, 14, 1344–1350.
  8. Tsuno, H.; Shen, J.; Komatsu, H.; Arichi, N.; Inuki, S.; Ohno, H.
    Gold(I)‐Catalyzed Bis‐Cyclization of Allenynes for the Synthesis of Strained and Planar Polycyclic Compounds.
    Angew. Chem. Int. Ed. 2023, 62, e202307532.
    DOI: 10.1002/anie.202307532
  9. Yoshida, Y.; Takeuchi, H.; Nakagawa, K.; Fujii, T.; Arichi, N.; Oishi, S.; Ohno, H.; Inuki, S. Construction of a Bicyclo[2.2.2]octene Skeleton via a Visible-Light-Mediated Radical Cascade Reaction of Amino Acid Derivatives with N-(2-Phenyl)benzoyl Groups.
    Org. Lett. 2023, 25, 4846–4851.
    DOI: 10.1021/acs.orglett.3c01586
  10. Nishiyama, K.; Akiba, H.; Nagata, S.; Tsumoto, K.; Kamada, H.; Ohno, H.
    A Proximity-Induced Fluorogenic Reaction Triggered by Antibody–Antigen Interactions with Adjacent Epitopes.
    Angew. Chem. Int. Ed. 2023, 62, e202306431.
    DOI: 10.1002/anie.202306431
  11. Greiner, L. C.; Arichi, N.; Inuki, S.; Ohno, H. Alkoxymigration onto α-Imino Gold Carbenes for Constructing Propellane-Type Indolines.
    Asian J. Org. Chem. 2023, 12, e202300232.
    DOI: 10.1002/ajoc.202300232
  12. Tsuji, A.; Masuya, T.; Arichi, N.; Inuki, S.; Murai, M.; Miyoshi, H.; Ohno, H.
    Discovery of Bis-sulfonamides as Novel Inhibitors of Mitochondrial NADH-Quinone Oxidoreductase (Complex I).
    ACS Med. Chem. Lett. 2023, 14, 211–216.
    DOI: 10.1021/acsmedchemlett.2c00504
  13. Greiner, L. C.; Arichi, N.; Inuki, S.; Ohno, H.
    Gold(I)-Catalyzed Benzylic C(sp3)-H Functionalizations: Divergent Synthesis of Indole[a]- and [b]-Fused Polycycles.
    Angew. Chem. Int. Ed. 2023, 62, e202213653.
    DOI: 10.1002/anie.202213653
  14. Miyamoto, J; Shimizu, H.; Hisa, K.; Matsuzaki, C.; Inuki, S.; Ando, Y.; Nishida, A.; Izumi, A.; Yamano, M.; Ushiroda, C.; Irie, J.; Katayama, T.; Ohno, H.; Itoh, H.; Yamamoto, K.; Kimura, I.
    Host metabolic benefits of prebiotic exopolysaccharides produced by Leuconostoc mesenteroides.
    Gut Microbes 2023, 15, 2161271.
    DOI: 10.1080/19490976.2022.2161271

2022

  1. Yagi, M.; Miller, S.; Nagai, Y.; Inuki, S.; Sato, A.; Hirora, T.
    A methylbenzimidazole derivative regulates mammalian circadian rhythms by targeting Cryptochrome proteins.
    F1000Research 2022, 11, 1016.
    DOI: 10.12688/f1000research.124658.2
  2. Yamamoto, A.; Takahashi, Y.; Inuki, S.; Nakagawa, S.; Nakao, K.; Ohno, H.; Doi, M.; Takakura, Y.
    The identification of novel small extracellular vesicle (sEV) production modulators using luciferase-based sEV quantification method.
    J. Extracell. Biol. 2022, 1, e62.
    DOI: 10.1002/jex2.62
  3. Inuki, S.; Tabuchi, H.; Matsuzaki, C.; Yonejima, Y.; Hisa, K.; Kimura, I.; Yamamoto, K.; Ohno, H.
    Chemical Synthesis and Evaluation of Exopolysaccharide Fragments Produced by Leuconostoc mesenteroides strain NTM048.
    Chem. Pharm. Bull. 2022, 70, 155–161.
    DOI: 10.1248/cpb.c21-00919
  4. Kitamura, T.; Suzuki, R.; Inuki, S.; Ohno, H.; McPhail, K. L.; Oishi, S.
    Design of coibamide A mimetics with improved cellular bioactivity.
    ACS Med. Chem. Lett. 2022, 13, 105–110.
    DOI: 10.1021/acsmedchemlett.1c00591

2021

  1. Komatsu, H.; Ikeuchi, T.; Tsuno, H.; Arichi, N.; Yasui, K.; Oishi, S.; Inuki, S.; Fukazawa, A.; Ohno, H.
    Construction of Tricyclic Nitrogen Heterocycles by Gold(I)-Catalyzed Cascade Cyclization of Allenynes and Its Application to Polycyclic π-Electron Systems.
    Angew. Chem. Int. Ed. 2021, 60, 27019–27025.
  2. Greiner, L. C.; Inuki, S.; Arichi, N.; Oishi, S.; Suzuki, R.; Iwai, T.; Sawamura, M.; Hashmi, A. S. K.; Ohno, H.
    Access to Indole-Fused Benzannulated Medium-Sized Rings through Gold(I)-Catalyzed Cascade Cyclization of Azido-Alkynes.
    Chem. Eur. J. 2021, 27, 12992–12997.
    DOI: 10.1002/chem.202101824
  3. Matsuoka, T.; Motozono, C.; Hattori, A.; Hideaki, K.; Yamasaki, S.; Oishi, S.; Ohno H.; Inuki, S.
    The Effects of 5‐OP‐RU Stereochemistry on Its Stability and MAIT‐MR1 Axis.
    ChemBioChem. 2021, 22, 672–678.
    DOI: 10.1002/cbic.202000466
  4. Yamaguchi, A.; Inuki, S.; Ohta, K.; Oishi, S.; Asai, A.; Ohno, H.
    Identification of a Novel Indoleamine 2,3-Dioxygenase Inhibitor Bearing an Eight-Membered Ring Fused Indole Scaffold and Its Structure-Activity Relationship.
    Heterocycles 2021, 103, 331–347.
  5. L. C. Greiner, J. Matsuoka, S. Inuki, H. Ohno
    Azido-Alkynes in Gold(I)-Catalyzed Indole Syntheses.
    Chem. Rec. 2021, 21, 3897–3910.
    DOI: 10.1002/tcr.202100202
  6. Ohno, H.; Inuki, S.
    Nonbiomimetic total synthesis of indole alkaloids using alkyne-based strategies.
    Org. Biomol. Chem. 2021, 19, 3551–3568.
    DOI: 10.1039/D0OB02577A
  7. Inuki, S.; Ohno, H.
    Total Syntheses of Myriocin, Mycestericins and Sphingofungin E: Sphingosine Analogues Containing a β, β'-Dihydroxyα-Amino Acid Framework.
    Chem. Lett. 2021, 50, 1313–1324.
    DOI: 10.1246/cl.210133
  8. Arichi, N.; Ohno, H.
    Natural Product Synthesis via Palladium-Catalyzed C–H Bond Activation.
    In Handbook of CH-Functionalization, Ed. by D. Maiti, Wiley-VCH, Weinheim, 2021.

2020

  1. Takeuchi, H.; Inuki, S.; Nakagawa, K.; Kawabe, T.; Ichimura, A.; Oishi, S.; Ohno H.
    Total Synthesis of Zephycarinatines via Photocatalytic Reductive Radical ipso-Cyclization.
    Angew. Chem. Int. Ed. 2020, 59, 21210–21215.
    DOI: 10.1002/anie.202009399
  2. Matsuoka, J.; Inuki, S.; Matsuda, Y.; Miyamoto, Y.; Otani, M.; Oka, M.; Oishi, S.; Ohno, H.
    Total Synthesis of Dictyodendrins A–F by the Gold-Catalyzed Cascade Cyclization of Conjugated Diyne with Pyrrole.
    Chem. Eur. J. 2020, 26, 11150–11157.
    DOI: 10.1002/chem.202001950
  3. Matsuoka, T.; Inuki, S.; Miyagawa, T.; Oishi, S.; Ohno, H.
    Total Synthesis of (+)-Polyoxamic Acid via Visible-Light-Mediated Photocatalytic β-Scission and 1,5-Hydrogen Atom Transfer of Glucose Derivative.
    J. Org. Chem. 2020, 85, 8271–8278.
    DOI: 10.1021/acs.joc.0c00910
  4. Kimura, I.; Miyamoto, J.; Ohue-Kitano, R.; Watanabe, K.; Yamada, T.; Onuki, M.; Aoki, R.; Isobe, Y.; Kashihara, D.; Inoue, D.; Inaba, A.; Takamura, Y.; Taira, S.; Kumaki, S.; Watanabe, M.; Ito, M.; Nakagawa, F.; Irie, J.; Kakuta, H.; Shinohara, M.; Iwatsuki, K.; Tsujimoto, G.; Ohno, H.; Arita, M.; Itoh, H.; Hase, K.
    Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice.
    Science 2020, 367, eaaw8429.
    DOI: 10.1126/science.aaw8429
  5. Sasaki, T.; Sonoda, T.; Tatebayashi, R.; Kitagawa, Y.; Oishi, S.; Yamamoto, K.; Fujii, N.; Inoue, N.; Uenoyama, Y.; Tsukamura, H.; Maeda, K.; Matsuda, F.; Morita, Y.; Matsuyama, S.; Ohkura, S.
    Peripheral administration of SB223412, a selective neurokinin-3 receptor antagonist, suppresses pulsatile luteinizing hormone secretion by acting on the gonadotropin-releasing hormone pulse generator in estrogen-treated ovariectomized female goats.
    J. Reprod. Dev. 2020, 59, 21210–2121.
    DOI: 10.1262/jrd.2019-145
  6. Miller, S.; Son, Y. L.; Aikawa, Y.; Makino, E.; Nagai, Y.; Srivastava, A.; Oshima, T.; Sugiyama, A.; Hara, A.; Abe, K.; Hirata, K.; Oishi, S.; Hagihara, S.; Sato, A.; Tama, F.; Itami, K.; Kay, S. A.; Hatori, M.; Hirota, T.
    Isoform-selective regulation of mammalian cryptochromes.
    Nat. Chem. Biol. 2020, 16, 676–685.
    DOI: 10.1038/s41589-020-0505-1
  7. Yamaguchi, A.; Inuki, S.; Tokimizu, Y.; Oishi, S.; Ohno, H.
    Gold(I)-Catalyzed Cascade Cyclization of Anilines with Diynes: Controllable Formation of Eight-Membered Ring-Fused Indoles and Propellane-Type Indolines.
    J. Org. Chem. 2020, 85, 2543–2559.
    DOI: 10.1021/acs.joc.9b03256

2019

  1. Tokunaga, M.; Miyamoto, Y.; Suzuki, T.; Otani, M.; Inuki, S.; Esaki, T.; Nagao, C.; Mizuguchi, K.; Ohno, H.; Yoneda, Y.; Okamoto, T.; Oka, M.; Matsuura, Y.
    Novel anti-flavivirus drugs targeting the nucleolar distribution of core protein.
    Viology 2019, 541, 41–51.
    DOI: 10.1016/j.virol.2019.11.015
  2. Rahayu, L.; Endo, N.; Kuwai, S.; Oishi, S.; Tanaka, T.
    The efficacy of a newly developed neurokinin 3 receptor agonist B21-750 on luteinizing hormone secretion in cycling goats.
    J. Reprod. Dev. 2019, 65, 481–484.
    DOI: 10.1262/jrd.2019-038
  3. Miyagawa, T.; Inuki, S.; Oishi, S.; Ohno, H.
    Construction of Quaternary Carbon Stereocenter of α-Tertiary Amine through Remote C–H Functionalization of Tris Derivatives: Enantioselective Total Synthesis of Myriocin.
    Org. Lett. 2019, 21, 5458–5490.
    DOI: 10.1021/acs.orglett.9b01778
  4. Matsuoka, J.; Kumagai, H.; Inuki, S.; Oishi, S.; Ohno, H.
    Construction of the pyrrolo[2,3-d]carbazole core of spiroindoline alkaloids by gold-catalyzed cascade cyclization of ynamide.
    J. Org. Chem. 2019, 84, 9358–9363.
    DOI: 10.1021/acs.joc.9b01149
  5. Ikeuchi, T.; Inuki, S.; Oishi, S.; Ohno, H.
    Gold(I)-catalyzed cascade cyclization reactions of allenynes for the synthesis of fused cyclopropanes and acenaphthenes.
    Angew. Chem. Int. Ed. 2019, 58, 7792–7796.
    DOI: 10.1002/anie.201903384
  6. Yamamoto, K.; Inuki, S.; Ohno, H.; Oishi, S.
    Scaffold hopping of fused piperidine-type NK3 receptor antagonists to reduce environmental impact.
    Bioorg. Med. Chem. 2019, 27, 2019–2026.
    DOI: 10.1016/j.bmc.2019.03.059
  7. Shu, K.; Iwamoto, N.; Honda, K.; Kondoh, Y.; Hirano, H.; Osada, H.; Ohno, H.; Fujii, N.; Oishi, S.
    Development of mirror-image screening systems for XIAP BIR3 domain inhibitors.
    Bioconjug. Chem. 2019, 30, 1395–1404.
    DOI: 10.1021/acs.bioconjchem.9b00154
  8. Sasaki, T.; Ito, D.; Sonoda, T.; Morita, Y.; Wakabayashi, Y.; Yamamura, T.; Okamura, H.; Oishi, S.; Noguchi, T.; Fujii, N.; Uenoyama, Y.; Tsukamura, H.; Maeda, K.-I.; Matsuda, F.; Ohkura, S.
    Peripheral administration of κ-opioid receptor antagonist stimulates gonadotropin-releasing hormone pulse generator activity in ovariectomized, estrogen-treated female goats.
    Domest. Anim. Endocrinol. 2019, 68, 83–91.
    DOI: 10.1016/j.domaniend.2018.12.011
  9. Yamamoto, K.; Yoshikawa, Y.; Ohue, M.; Inuki, S.; Ohno, H.; Oishi, S.
    Synthesis of triazolo- and oxadiazolo-piperazines by gold(I)-catalyzed domino cyclization: application to the design of a MAP kinase inhibitor.
    Org. Lett. 2019, 21, 373–377.
    DOI: 10.1021/acs.orglett.8b03500

2018

  1. Kawada, Y.; Ohmura, S.; Kobayashi, M.; Nojo, W.; Kondo, M.; Matsuda, Y.; Matsuoka, J.; Inuki, S.; Oishi, S.; Wang, C.; Saito, T.; Uchiyama, M.; Suzuki, T.; Ohno, H.
    Direct synthesis of aryl-annulated [c]carbazoles by gold(I)-catalysed cascade reaction of azide-diynes and arenes.
    Chem. Sci. 2018, 44, 8416–8425.
    DOI: https://doi.org/10.1039/C8SC03525C
  2. Hamada, N.; Yamaguchi, A.; Inuki, S.; Oishi, S.; Ohno, H.
    Gold(I)-catalyzed oxidative cascade cyclization of 1,4-diyn-3-ones for the construction of tropone-fused furan scaffolds.
    Org. Lett. 2018, 20, 4401–4405.
  3. Inuki, S.; Miyagawa, T.; Oishi, S.; Ohno, H.
    Introduction of a polar functional group to the lipid tail of 4-epi-jaspine B affects sphingosine kinase isoform selectivity.
    Chem. Pharm. Bull. 2018, 66, 866–872.
  4. Kaneda, M.; Kawaguchi, S.; Fujii, N.; Ohno, H.; Oishi, S.
    SAR study on odoamide: insights into the bioactivities of aurilide-family hybrid peptide-polyketides.
    ACS Med. Chem. Lett. 2018, 9, 365–369.
  5. Ohara, T.; Kaneda, M.; Saito, T.; Fujii, N.; Ohno, H. Oishi, S.
    Head-to-tail macrocyclization of cysteine-free peptides using an o-aminoanilide linker.
    Bioorg. Med. Chem. Lett. 2018, 28, 1283–1286. 
  6. Sekiguchi, H.; Kuroyanagi,T.; Rhainds, D.; Kobayashi, K.; Kobayashi, Y.; Ohno, H.; Heveker, N.; Akaji, K.; Fujii, N.; Oishi, S.
    Structure–activity relationship study of cyclic pentapeptide ligands for atypical chemokine receptor 3 (ACKR3).
    J. Med. Chem. 2018, 61, 3745–3751.
  7. Kobayashi, Y.; Hoshino, M.; Kameda, T.; Kobayashi, K.; Akaji, K.; Inuki, S.; Ohno, H.; Oishi, S.
    Use of a compact tripodaltris(bipyridine) ligand to stabilize a single metal-centered chirality: stereoselective coordination of iron(II) and ruthenium(II) on a semi-rigid hexapeptide macrocycle.
    Inorg. Chem. 2018, 57, 5475–5485.
  8. Miyazaki, Y.; Ichimura, A.; Sato, S.; Fujii, T.; Oishi, S.; Sakai, H.; Takeshima, H.
    The natural flavonoid myricetin inhibits gastric H+, K+-ATPase.
    Eur. J. Pharmacol. 2018, 820, 217–221. 
  9. Tsuda, S.; Mochizuki, M.; Ishiba, H.; Yoshizawa-Kumagaye, K.; Nishio, H.; Oishi, S.; Yoshiya, T.
    Easy-to-attach/detach solubilizing tag-aided chemical synthesis of an aggregative capsid protein.
    Angew. Chem. Int. Ed. 2018, 57, 2105–2109.
  10. Miyagawa, T.; Inuki, S.; Honda, M.; Nakamura, S.; Nakanishi, I.; Fujii, N.; Oishi, S.; Ohno, H.
    Synthesis of jaspine B regioisomers through palladium-catalyzed stereoselective tetrahydrofuran formation: insight into the ligand recognition of sphingosine kinases.
    Tetrahedron 2018, 74, 1802–1809.
  11. Kaneda, M.; Inuki, S.; Ohno, H.; Oishi, S.
    Total Synthesis and Stereochemical Revision of Stereocalpin A: Mirror-Image Approach for Stereochemical Assignments of the Peptide–Polyketide Macrocycle.
    J. Org. Chem. 2018, 83, 3047–3060.

2017

  1. Kode, J.; Khattry, N.; Bakshi, A.; Amrutkar, V.; Bagal, B.; Karandikar, R.; Rane, P.; Fujii, N.; Chiplunkar, S.
    Study of stem cell homing & self-renewal marker gene profile of ex vivo expanded human CD34+ cells manipulated with a mixture of cytokines & stromal cell-derived factor 1
    Indian. J. Med. Res. 2017, 146, 56–70. 
  2. Kobayashi, Y.; Kameda, T.; Hoshino, M.; Fujii, N.; Ohno, H.; Oishi, S.
    Fe(II)-complexation of tripodalhexapeptide ligands with three bidentate triazolylpyridines: induction of metal-centred chirality by peptide macrocyclization.
    Dalton Trans. 2017, 46, 13673–13676.
  3. Nakamura, S.; Ito, Y.; Yamamoto, K.; Takahashi, C.; Dai, M.; Tanahashi, M.; Uenoyama, Y.; Tsukamura, H.; Oishi, S.; Maeda, K.; Matsuda, F.
    SB223412, a neurokinin-3 receptor-selective 1 antagonist, suppresses testosterone secretion in male guinea pigs.
    Theriogenology 2017, 102, 183–189. 
  4. Shu, K.; Noguchi, T.; Honda, K.; Kondoh, Y.; Osada, H.; Ohno, H.; Fujii, N.: Oishi, S.
    Synthesis of the Src SH2 domain and its application in bioassays for mirror-image screening.
    RSC Adv. 2017, 7, 38725–38732.
  5. Hamada N.; Yoshida Y.; Oishi S.; Ohno H.
    Gold-Catalyzed Cascade Reaction of Skipped Diynes for the Construction of a Cyclohepta[b]pyrrole Scaffold.
    Org. Lett. 2017, 19, 3875–3878. 
  6. Matsuoka, J.; Matsuda, Y.; Kawada, Y.; Oishi, S.; Ohno H.
    Total Synthesis of Dictyodendrins by the Gold-Catalyzed Cascade Cyclization of Conjugated Diynes with Pyrroles.
    Angew. Chem. Int. Ed. 2017, 56, 7444–7448. 
  7. Ikegami, K.; Minabe, S.; Ieda, N.; Goto, T.; Sugimoto, A.; Nakamura, S.; Inoue, N.; Oishi, S. Maturana, A. D.; Sanbo, M.; Hirabayashi, M.; Maeda, K.-I.; Tsukamura, H.; Uenoyama, Y.
    Evidence of involvement of neurone-glia/neurone-neurone communications via gap junctions in synchronised activity of KNDy neurones.
    J. Neuroendocrinol. 2017, 29.
    DOI: 10.1111/jne.12480
  8. Ishiba, H.; Noguchi, T.; Shu, K.; Ohno, H.; Honda, K.; Kondoh, Y.; Osada, H.; Fujii, N.; Oishi, S.
    Investigation of the inhibitory mechanism of apomorphine against MDM2–p53 interaction.
    Bioorg. Med. Chem. Lett. 2017, 27, 2571–2574. 
  9. Ohno, H.; Honda, M.; Hamada, N.; Miyagaki, J.; Iwata, A.; Otsuki, K.; Maruyama, T.; Nakamura, A.; Nakanishi, I.; Inuki, S.; Fujii, N.; Oishi, S.
    Identification of selective inhibitors of sphingosine kinases 1 and 2 through a structure–activity relationship study of 4-epi-jaspine B.
    Bioorg. Med. Chem. 2017, 25, 3046–3052.
  10. Noguchi, T.; Ishiba, H.; Honda, K.; Kondoh, Y.; Osada, H.; Ohno, H.; Fujii, N.; Oishi, S.
    Synthesis of Grb2 SH2 domain proteins for mirror-image screening systems.
    Bioconjug. Chem. 2017, 28, 609–619.
  11. Yano, Y.; Kondo, K.; Watanabe, Y.; Zhang, T. O.; Ho, J. J.; Oishi, S.; Fujii, N.; Zanni, M. T.; Matsuzaki, K.
    GXXXG-mediated parallel and antiparallel dimerization of transmembrane helices and its inhibition by cholesterol: single-pair FRET and 2D IR studies.
    Angew. Chem. Int. Ed. 2017, 56, 1756–1759.

2016

  1. Alam, M.; Kuwata, T.; Shimura, K.; Yokoyama, M.; Ramirez Valdez, K. P.; Tanaka, K.; Maruta, Y.; Oishi, S.; Fujii, N.; Sato, H.; Matsuoka, M.; Matsushita, S.
    Enhanced antibody-mediated neutralization of HIV-1 variants that are resistant to fusion inhibitors.
    Retrovirology. 13(1), 70, (2016)
  2. Sawada, J.; Osawa, A.; Takeuchi, T.; Kaneda, M.; Oishi, S.; Fujii, N.; Asai, A.; Tanino, K.; Namba, K.
    Functional 1,3a,6a-triazapentalene scaffold: Design of fluorescent probes for kinesin spindle protein (KSP).
    Bioorg. Med. Chem. Lett. 26(23) 5765-5769. (2016) 
  3. Watanabe, M.; Hashimoto, K.; Abe, Y.; Kodama, E.N.; Nabika, R.; Oishi, S.; Ohara, S.; Sato, M.; Kawasaki, Y.; Fujii, N.; Hosoya, M.
    A novel peptide derived from the fusion protein heptad repeat inhibits replication of subacute sclerosing panencephalitis virus in vitro and in vivo.
    PLoS One. 11(9) e0162823. 
  4. Hattori, Y.; Machida,Y.;Honda, M.;Ohno, H.;Fujii, N.;Onishi, H.
    Small interfering RNA delivery into the liver by cationic cholesterol derivative-based liposomes.
    J. Liposome Res. (2016) 
  5. Suzuki, T.; Nojo, W.; Sakano, Y.; Katoono, R.; Ishigaki, Y.; Ohno, H.; Fujiwara, K.
    Redox-induced conformational changes in 1,3-propylene- and m-xylylenebis[5-(10-butyl-5,10-dihydrobenzo[a]indolo[2,3-c]carbazole)]: twin-BIC donors that form sandwich-like dimeric cations exhibiting NIR absorption.
    Chem. Lett. 45(7) 720-722. (2016)
  6. Kaneda, M.; Sueyoshi, K.; Teruya, T.; Ohno, H.; Fujii, N.; Oishi, S.
    Total synthesis of odoamide, a novel cyclic depsipeptide from an Okinawan marine cyanobacterium.
    Org. Biomol. Chem. 14(38) 9093-9104. (2016) 
  7. Abdelouahab, H.; Zhang, Y.; Wittner, M.; Oishi, S.; Fujii, N.; Besancenot, R.; Plo, I.; Ribrag, V.; Solary, E.; Vainchenker, W.; Barosi, G.; Louache, F.
    CXCL12/CXCR4 pathway is activated by oncogenic JAK2 in a PI3K-dependent manner.
    Oncotarget, DOI: 10.18632/oncotarget.10789. 
  8. Sueyoshi, K.; Kaneda, M.; Sumimoto, S.; Oishi, S.; Fujii, N.; Suenaga, K.; Teruya, T.
    Odoamide, a cytotoxic cyclodepsipeptide from the marine cyanobacterium Okeania sp.
    Tetrahedron, 72(35) 5472-5478. (2016)
  9. Naoe, S.; Yoshida, Y.; Oishi, S.; Fujii, N.; Ohno, H.
    Total synthesis of (+)-conolidine by the gold(I)-catalyzed cascade cyclization of a conjugated enyne.
    J. Org. Chem. 81(13) 5690-5698. (2016) 
  10. Yamamoto, K.; Okazaki, S.; Ohno, H.; Matsuda, F.; Ohkura, S.; Maeda, K.; Fujii, N.; Oishi, S.
    Development of novel NK3 receptor antagonists with reduced environmental impact.
    Bioorg. Med. Chem. 24(16) 3494-3500. (2016) 
  11. Noguchi, T.; Oishi, S.; Honda, K.; Kondoh, Y.; Saito, T.; Ohno, H.; Osada, H.; Fujii, N.
    Screening of a virtual mirror-image library of natural products.
    Chem. Commun. 52(49) 7653-7656. (2016) 
  12. Kato, F.; Ishida, Y.; Oishi, S.; Fujii, N.; Watanabe, S.; Vasudevan, S. G.; Tajima, S.; Takasaki, T.; Suzuki, Y.; Ichiyama, K.; Yamamoto, N.; Yoshii, K.; Takashima, I.; Kobayashi, T.; Miura, T.; Igarashi, T.; Hishiki, T.
    Novel antiviral activity of bromocriptine against dengue virus replication.
    Antiviral Res.     131 141-147. (2016) 
  13. Nishiyama, D.; Sakai, Y.; Sekiguchi, H.; Chiba, H.; Misu, R.; Oishi, S.; Fujii, N.; Ohno, H.
    Novel 3,4,7-substituted benzofuran derivatives having binding affinity to κ-opioid receptor.
    Chem. Pharm. Bull. 64(7) 996-1003. (2016) 
  14. Nishiyama, D.; Ohara, A.; Chiba, H.; Kumagai, H.; Oishi, S.; Fujii, N.; Ohno, H.
    Formal total synthesis of (±)-strictamine based on a gold-catalyzed cyclization.
    Org. Lett. 18(7) 1670-1673. (2016) 
  15. Ohno, H.; Minamiguchi, D.; Nakamura, S.; Shu, K.; Okazaki, S.; Honda, M.; Misu, R.; Moriwaki, H.; Nakanishi, S.; Oishi, S.; Kinoshita, T.; Nakanishi, I.; Fujii, N.
    Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors.
    Bioorg. Med. Chem. 24(5) 1136-1141. (2016) 
  16. Wagner, B.; Hiller, W.; Ohno, H.; Krause, N.
    Gold-catalyzed three-component spirocyclization: a one-pot approach to functionalized pyrazolidines.
    Org. Biomol. Chem. 14(5) 1579-1583. (2016) 

2015

  1. Shi, J.; Liu, N.; Xiao, Y.; Takei, Y.; Yasue, M.; Suzuki, Y.; Hou, Z.; Ohno, H.; Tsujimoto, G.; Hirasawa, A.
    The effects of a selective CK2 inhibitor on anti-glomerular basement membrane glomerulonephritis in rats.
    Biol. Pharm. Bull. 38(9) 1345-1351. (2015) 
  2. Miyamoto, F.; Kawaji, K.; Oishi, S.; Fujii, N.; Kaku, M.; Kodama, E. N.
    Anti-HIV-1 activity determined by β-galactosidase activity in the multinuclear activation of an indicator assay is comparable with that by a conventional focus counting method.
    Antivir. Chem. Chemother. 24 77-82. (2015) 
  3. Taguchi, M.; Tokimizu, Y.; Oishi, S.; Fujii, N.; Ohno, H.
    Synthesis of fused carbazoles by gold-catalyzed tricyclization of conjugated diynes via rearrangement of an Ν-propargyl group.
    Org. Lett. 17(24) 6250-6253. (2015) 
  4. Umatani, C.; Misu, R.; Oishi, S.; Yamaguchi, K.; Abe, H.; Oka, Y.
    GnRH suppresses excitability of visual-processing neurons in the optic tectum.
    J. Neurophysiol. 114(5) 2775-2784. (2015) 
  5. Shimura, K.; Miyazato, P.; Oishi, S.; Fujii, N.; Matsuoka, M.
    Impact of HIV-1 infection pathways on susceptibility to antiviral drugs and on virus spread.
    Virology 484 364-376. (2015) 
  6. Oishi, S.; Kuroyanagi, T.; Kubo, T.; Montpas, N.; Yoshikawa, Y.; Misu, R.; Kobayashi, Y.; Ohno, H.; Heveker, N.; Furuya, T.; Fujii, N.
    Development of novel CXC chemokine receptor 7 (CXCR7) ligands: selectivity switch from CXCR4 antagonists with a cyclic pentapeptide scaffold.
    J. Med. Chem. 58(13) 5218-5225. (2015) 
  7. Iwata, A.; Inuki, S.; Oishi, S.; Fujii, N.; Ohno, H.
    Convenient synthesis of spiroindole derivatives via palladium-catalyzed cyclization of propargyl chlorides.
    Tetrahedron 71(37) 6580-6585. (2015)
  8. Takenaga, M.; Yamamoto, Y.; Takeuchi, T.; Ohta, T; Tokura, Y.; Hamaguchi, A.; Asai, D.; Nakashima, H.; Oishi, S.; Fujii, N.
    Potential new chemotherapy strategy for human ovarian carcinoma with a novel KSP inhibitor.
    Biochem. Biophys. Res. Commun. 463(3) 222-228. (2015) 
  9. Tokimizu, Y.; Oishi, S.; Fujii, N.; Ohno, H.
    Gold-catalyzed cascade cyclization of 2-alkynyl-N-propargylanilines via the rearrangement of a propargyl group.
    Angew. Chem. Int. Ed. 54(27) 7862-7866. (2015) 
  10. Naoe, S.; Saito, T.; Uchiyama, M.; Oishi, S.; Fujii, N.; Ohno, H.
    Direct construction of fused indoles by gold-catalyzed cascade cyclization of conjugated diynes.
    Org. Lett. 17(7) 1774-1777. (2015) 
  11. Yasuda, Y.; Arakawa, T.; Nawata, Y.; Shimada, S.; Oishi, S.; Fujii, N.; Nishimura, S.; Hattori, A.; Kakeya, H.
    Design, synthesis, and structure-activity relationships of 1-ethylpyrazole-3-carboxamide compounds as novel hypoxia-inducible factor (HIF)-1 inhibitors.
    Bioorg. Med.     Chem. 23(8) 1776-1787. (2015)
  12. Montpas, N.; Cabana, J.; St-Onge, G.; Gravel, S.; Morin, G.; Kuroyanagi, T.; Lavigne, P.; Fujii, N.; Oishi, S.; Heveker, N.
    The binding mode of the cyclic agonist peptide TC14012 to CXCR7 - Identification of receptor and compound determinants.
    Biochemistry 54(7) 1505-1515. (2015) 
  13. Okazaki, S.; Oishi, S.; Mizuhara, T.; Shimura, K.; Murayama, H.; Ohno, H.; Matsuoka, M.; Fujii, N.
    Investigations of possible prodrug structures for 2-(2-mercaptophenyl)tetrahydropyrimidines: reductive conversion from anti-HIV agents with pyrimidobenzothiazine and isothiazolopyrimidine scaffolds.
    Org. Biomol. Chem. 13(16) 4706-4713. (2015) 
  14. Hattori, Y.; Hara, E.; Shingu, Y.; Minamiguchi, D.; Nakamura, A.; Arai, S.; Ohno, H.; Kawano, K.; Fujii, N.; Yonemochi, E.
    siRNA delivery into tumor cells by cationic cholesterol derivative-based nanoparticles and liposomes.
    Biol. Pharm. Bull. 38(1) 30-38. (2015)
  15. Okazaki, S.; Mizuhara, T.; Shimura, K.; Murayama, H.; Ohno, H.; Oishi, S.; Matsuoka, M.; Fujii, N.
    Identification of anti-HIV agents with a novel benzo[4,5]isothiazolo[2,3-a]pyrimidine scaffold.
    Bioorg. Med. Chem. 23(7) 1447-1452. (2015) 
  16. Kawabata, H.; Uchiyama, T.; Sakamoto, S.; Kanda, J.; Oishi, S.; Fujii, F.; Tomosugi, N.; Kadowaki, N.; Takaori-Kondo, A.
    A HAMP promoter bioassay system for identifying chemical compounds that modulate hepcidin expression.
    Exp. Hematol. 43(5) 404-413. (2015) 
  17. Tokimizu, Y.; Wieteck, M.; Rudolph, M.; Oishi, S.; Fujii, N.; Hashmi, A. S. K.; Ohno, H.
    Dual gold catalysis: a novel synthesis of bicyclic and tricyclic pyrroles from N-propargyl ynamides.
    Org. Lett. 17(3) 604-607. (2015) 
  18. Misu, R.; Yamamoto, K.; Yamada, A.; Noguchi, T.; Ohno, H.; Yamamura, T.; Okamura, H.; Matsuda, F.; Ohkura, S.; Oishi, S.; Fujii, N.
    Structure-activity relationship study on senktide for development of novel potent neurokinin-3 receptor selective agonists.
    MedChemCommun. 6(3) 469-476. (2015)
  19. Tsunematsu, Y.; Nishimura, S.; Hattori, A.; Oishi, S.; Fujii, N.; Kakeya, H.
    Isolation, structure elucidation and total synthesis of tryptopeptins A and B, new TGF-beta signaling modulators from Streptomyces sp.
    Org. Lett. 17(2) 258-261. (2015) 
  20. Nabika, R.; Suyama, T. L.; Hau, A. M.; Misu, R.; Ohno, H.; Ishmael, J. E.; McPhail, K. L.; Oishi, S.; Fujii, N.
    Synthesis and biological evaluation of the [D-MeAla11]-epimer of coibamide A.
    Bioorg. Med. Chem. Lett. 25(2) 302-306. (2015) 
  21. Matsuda, Y.; Naoe, S.; Oishi, S.; Fujii, N.; Ohno, H.
    Formal [4+2] reaction between 1,3-diynes and pyrroles: gold(I)-catalyzed indole synthesis by double hydroarylation.
    Chem. Eur. J. 21(4) 1463-1467. (2015) 
  22. Zenda, M.; Yasui, H.; Oishi, S.; Masuda, R.; Fujii, N.; Koide, T.
    A cisplatin derivative that inhibits collagen fibril-formation in vitro.
    Chem. Biol. Drug Des. 85(5) 519-526. (2015)

2014

  1. Wieteck, M.; Tokimizu, Y.; Rudolph, M.; Rominger, F.; Ohno, H.; Fujii, N.; Hashmi, A. S.
    Dual gold catalysis: synthesis of polycyclic compounds via C-H insertion of gold vinylidenes.
    Chem. Eur. J. 20(49) 16331-16336. (2014) 
  2. Misu, R.; Oishi, S.; Yamada, A.; Yamamura, T.; Matsuda, F.; Yamamoto, K.; Noguchi, T.; Ohno, H.; Okamura, H.; Ohkura, S.; Fujii, N.
    Development of novel neurokinin 3 receptor (NK3R) selective agonists with resistance to proteolytic degradation.
    J. Med. Chem. 57(20) 8646-8651. (2014) 
  3. Nabika, R.; Oishi, S.; Misu, R.; Ohno, H.; Fujii, N.
    Synthesis of IB-01212 by multiple N-methylations of peptide bonds.
    Bioorg. Med. Chem. 22(21) 6156-6162. (2014) 
  4. Tokimizu, Y.; Oishi, S.; Fujii, N.; Ohno, H.
    Gold-catalyzed cascade cyclization of (azido)ynamides: an efficient strategy for the construction oflndoloquinolines.
    Org. Lett. 16(11) 3138-3141. (2014) 
  5. Tsutsui, A.; Imamaki, R.; Kitazume, S.; Hanashima, S.; Yamaguchi, Y.; Kaneda, M.; Oishi, S.; Fujii, N.; Taniguchi, N.; Tanaka, K.
    Polyamine modification by acrolein exclusively produces 1,5-diazacyclooctanes: a previously unrecognized mechanism for acrolein-mediated oxidative stress.
    Org. Biomol. Chem. 12(28) 5151-5157. (2014) 
  6. Suzuki, T.; Sakano, Y.; Tokimizu, Y.; Miura, Y.; Katoono, R.; Fujiwara, K.; Yoshioka, N.; Fujii, N.; Ohno, H.
    Wurster's blue-type cation radicals framed in a 5,10-dihydrobenzo[a]indolo[2,3-c]carbazole (BIC) skeleton: dual electrochromism with drastic changes in UV-Vis-NIR and fluorescence.
    Chem. Ajian J. 9(7) 1841-1846. (2014) 
  7. Graf, K.; Hindenberg, P.D.; Tokimizu,Y.; Naoe, S.; Rudolph, M.; Rominger, F.; Ohno, H.; Hashmi, A.S.K.
    The role of acetylides in dual gold catalysis: a mechanistic investigation of the selectivity difference in the naphthalene synthesis from diynes.
    ChemCatChem 6(1), 199-204. (2014)
  8. Kaneda, M.; Misu, R.; Ohno, H.; Hirasawa, A.; Ieda, N.; Uenoyama, Y.; Tsukamura, H.; Maeda, K.; Oishi, S.; Fujii, N.
    Design and synthesis of fluorescent probes for GPR54.
    Bioorg. Med. Chem. 22(13) 3325-3330. (2014) 
  9. Takeuchi, T.; Oishi, S.; Kaneda, M.; Misu, R.; Ohno, H.; Sawada, J.; Asai, A.; Nakamura, S.; Nakanishi, I.; Fujii, N.
    Optimization of diaryl amine derivatives as kinesin spindle protein inhibitors.
    Bioorg. Med. Chem. 22(12) 3171-3179. (2014) 
  10. Takeuchi, T.; Oishi, S.; Kaneda, M.; Ohno, H.; Nakamura, S.; Nakanishi, I.; Yamane, M.; Sawada, J.; Asai, A.; Fujii, N.
    Kinesin spindle protein inhibitors with diaryl amine scaffolds: crystal packing analysis for improved aqueous solubility.
    ACS Med. Chem. Lett. 5(5) 566-571. (2014) 
  11. Sano, K.; Masuda, R.; Hisada,H.; Oishi, S.; Shimokawa, K.; Ono, M.; Fujii, N.; Saji, H.; Mukai, T.
    A radiogallium-DOTA-based bivalent peptidic ligand targeting a chemokine receptor, CXCR4, for tumor imaging.
    Bioorg. Med. Chem. Lett. 24(5) 1386-1388. (2014) 
  12. Iwata, A.; Inuki, S.; Oishi, S.; Fujii, N.; Ohno, H.
    Synthesis of fused tetracyclic spiroindoles via palladium-catalysed cascade cyclisation.
    Chem. Commun.     2014, 50, 298–300.