《田中　智之助手　業績》

【2005】
• Critical role of PKC[beta]II in activation of mast cells by monomeric IgE. Liu, Y., Furuta, K., Teshima, R., Shirata, N., Sugimoto, Y., Ichikawa, A. and Tanaka, S. (2005) J. Biol. Chem., 280, 38976-38981.
• Prostaglandin E2 stimulates granulocyte colony-stimulating factor production via the prostanoid EP2 receptor in mouse peritoneal neutrophils. Sugimoto, Y., Fukada, Y., Mori, D., Tanaka, S., Yamane, H., Okuno, Y., Deai, K., Tsuchiya, S., Tsujimoto, G. and Ichikawa, A. (2005) J. Immunol., 175, 2606-2612.
• Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3. Kunikata, T., Yamane, H., Segi, E., Matsuoka, T., Sugimoto, Y., Tanaka, S., Tanaka, H., Nagai, H., Ichikawa, A. and Narumiya, S. (2005) Nat. Immunol., 6, 524-531.
• Ca2+ influx-mediated histamine synthesis and IL-6 release in mast cells activated by monomeric IgE. Tanaka, S., Mikura, S., Hashimoto, E., Sugimoto, Y. and Ichikawa, A. (2005) Eur. J. Immunol., 35, 460-468.
  
  【2004】
• Lack of histamine alters gastric mucosal morphology: Comparison between histidine decarboxylase-deficient and mast cell-deficient mice. Nakamura, E., Kataoka, T., Furutani, K., Jimbo, K., Aihara, T., Tanaka, S., Ichikawa, A., Ohtsu, H., and Okabe, S. (2004) Am. J. Physiol.-Gastrointest. Liver. Physiol., 287, 1053-1061.
• Chemical genetic identification of the histamine H1 receptor as a stimulator of insulin-induced adipogenesis. Kawazoe, Y., Tanaka, S. and Uesugi, M. (2004) Chem. Biol., 11, 907-913.
• Expression of L-histidine decarboxylase in granules of elicited mouse polymorphonuclear leukocytes. Tanaka, S., Deai, K., Konomi, A., Takahashi, K., Yamane, H., Sugimoto, Y. and Ichikawa, A. (2004) Eur. J. Immunol., 34, 1472-1482.
• A cluster of aromatic amino acids in the i2 loop plays a key role for Gs coupling in prostaglandin EP2 and EP3 receptors. Sugimoto, Y., Nakato, T., Kita, A., Takahashi, Y., Hatae, N., Tabata, H., Tanaka, S. and Ichikawa, A. (2004) J. Biol. Chem., 279, 11016-11026.
  
  【2003】
• Crucial role for histamine in regulating gastric acid secretion revealed with histidine decarboxylase-knockout mice. Furutani, K., Aihara, T., Nakamura, E., Tanaka, S., Ichikawa, A., Ohtsu, H. and Okabe, S. (2003) J. Pharmacol. Exp. Ther., 307, 331-338.
• Functional domains essential for Gs activity in prostaglandin EP2 and EP3 receptors. Sugimoto, Y., Nakato, T., Kita, A., Hatae, N., Tabata, H., Tanaka, S. and Ichikawa, A. (2003) Life Sci., 74, 135-141.
• Identification and characterization of a novel progesterone receptor-binding element in the mouse prostaglandin E receptor subtype EP2 gene. Tsuchiya, S., Tanaka, S., Sugimoto, Y., Katsuyama, M., Ikegami, R. and Ichikawa, A. (2003) Genes to Cells, 8, 747-758.
• Uptake of histamine by mouse peritoneal macrophages and a macrophage cell line, RAW 264.7. Tanaka, S., Deai, K., Inagaki, M. and Ichikawa, A. (2003) Am. J. Physiol. Cell Physiol.,285, C592-598.
• Mouse mammary epithelial histamine system. Wagner, W., Ichikawa, A., Tanaka, S., Panula, P. and Fogel, W. A. (2003) J. Physiol. Pharmacol., 54, 211-223.
• Phosphorothioate antisense oligodeoxynucleotides against histidine decarboxylase: a study in mouse mammary epithelial cell cultures. Wagner, W., Tanaka, S., Ichikawa, A. and Fogel, W. A. (2003) Inflamm. Res., 52, S59-S62.
• Induction of adherent activity in mastocytoma P-815 cells by the cooperation of two prostaglandin E2 receptor subtypes, EP3 and EP4. Hatae, N., Kita, A., Tanaka, S., Sugimoto, Y. and Ichikawa, A. (2003) J. Biol. Chem., 278, 17977-17981.
• Expression of messenger RNA for prostaglandin E receptor subtypes EP4/EP2 and cyclooxygenase isozymes in mouse periovulatory follicles and oviducts during superovulation. Segi, E., Haraguchi, K., Sugimoto, Y., Tsuji, M., Tsunekawa, H., Tamba, S., Tsuboi, K., Tanaka, S. and Ichikawa, A. (2003) Biol. Reprod., 68, 804-811.
• Expanded parietal cell pool in transgenic mice unable to synthesize histamine. Hunyady, B., Zolyomi, A., Czimmer, J., Mozsik, G., Kozicz, T., Buzas, E., Tanaka, S., Ichikawa, A., Nagy, A., Palkovits, M. and Falus, A. (2003) Scand. J. Gastroenterol., 38, 133-140.
  
  【2002】
• Possible coupling of prostaglandin E receptor EP1 to TRP5 expressed in Xenopus laevis oocytes. Tabata, H., Tanaka, S., Sugimoto, Y., Kanki, H., Kaneko, S. and Ichikawa, A. (2002) Biochem. Biophys. Res. Commun., 298, 398-402.
• Histamine H2 receptor-mediated modulation of local cytokine expression in a mouse experimental tumor model. Takahashi, K., Tanaka, S., Furuta, K. and Ichikawa, A. (2002) Biochem. Biophys. Res. Commun., 297, 1205-1210.
• Antigen-independent induction of histamine synthesis by immunoglobulin E in mouse bone marrow -derived mast cells. Tanaka, S., Takasu, Y., Mikura, S., Satoh, N. and Ichikawa, A. (2002) J. Exp. Med., 196, 229-235.
• Expression of L-histidine decarboxylase in mouse male germ cells. Safina, F., Tanaka, S., Inagaki, M., Tsuboi, K., Sugimoto, Y. and Ichikawa, A. (2002) J. Biol. Chem., 277, 14211-14215.
• Gastric acid secretion in L-histidine decarboxylase-deficient mice. Tanaka, S., Hamada, K., Yamada, N., Sugita, Y., Tonai, S., Hunyady, B., Palkovits, M., Falus, A., Watanabe, T., Okabe, S., Ohtsu, H., Ichikawa, A. and Nagy, A. (2002) Gastroenterology, 122, 145-155.
• Histamine synthesis in mouse polymorphonuclear neutrophis. Tanaka, S., Konomi, A., Takahashi, K. and Ichikawa, A. (2002) Inflamm. Res., 51, S17-S18.
• Plasma extravasation induced by dietary supplemented histamine in histamine-free mice. Ohtsu, H., Kuramasu, A., Tanaka, S., Terui, T., Hirasawa, N., Hara, M., Makabe-Kobayashi, Y., Yamada, N., Yanai, K., Sakurai, E., Okada, M., Ohuchi, K., Ichikawa, A., Nagy, A. and Watanabe, T. (2002) Eur. J. Immunol., 32, 1698-1708.
  
  【2001】
• Mice lacking histidine decarboxylase exhibit abnormal mast cells. Ohtsu, H., Tanaka, S., Terui, T., Hori, Y., Makabe-Kobayashi, Y., Pejler, G., Tchougounova, E., Hellman, L., Gertsenstein, M., Hirasawa, N., Sakurai, E., Buzas, E., Kovacs, P., Csaba, G., Kittel, A., Okada, M., Hara, M., Mar, L., Numayama-Tsuruta, K., Ishigaki-Suzuki, S., Ohuchi, K., Ichikawa, A., Falus, A., Watanabe, T. and Nagy, A. (2001) FEBS Lett., 502, 53-56.
• Role of histamine in gastric acid secretion: L-histidine decarboxylase deficient mice. Tanaka, S., Hamada, K., Ohtsu, H., Watanabe, T., Falus, A., Nagy, A., Okabe, S. and Ichikawa, A. (2001) Histamine Research in the New Millennium (Watanabe, T., eds.), Elsevier Science B.V., 329-334.
• Intracellular localization of histidine decarboxylase. Tanaka, S. and Ichikawa, A. (2001) Inflamm. Res., 50, 2, S98-S99.
• Effect of cimetidine on intratumoral cytokine expression in an experimental tumor. Takahashi, K., Tanaka, S. and Ichikawa, A. (2001) Biochem. Biophys. Res. Commun., 281, 1113-1119.
  
  【2000】
• Prostaglandin E2 receptors, EP2 and EP4, differentially modulate TNF-alpha and IL-6 production induced by lipopolysaccharide in mouse peritoneal neutrophils. Yamane, H., Sugimoto, Y., Tanaka, S. and Ichikawa, A. (2000) Biochem. Biophys. Res. Commun., 278, 224-228.
  
  【1998】
• Membrane targeting and binding of the 74-kDa form of mouse L-histidine decarboxylase via its carboxyl-terminal sequence. Suzuki, S., Tanaka, S., Nemoto, K. and Ichikawa, A. (1998) FEBS Lett., 437, 44-48.
• Benzamidine-sensitive proteinase in activated cleavage of recombinant 74kDa histidine decarboxylase into its 53kDa form in mastocytoma cells. Ichikawa, A., Funakoshi, E., Tanaka, S., Nemoto, K. and Fukui, T. (1998) Inflamm. Res., 47, 1, S46-S47.
• Intracellular localization of the 74- and 53-kDa forms of L-histidine decarboxylase in a rat basophilic/mast cell line, RBL-2H3. Tanaka, S., Nemoto, K., Yamamura, E. and Ichikawa, A. (1998) J. Biol. Chem., 273, 14, 8177-8182.
  
  【1997】
• Degradation of the 74 kDa form of L-histidine decarboxylase via the ubiquitin-proteasome pathway in a rat basophilic/mast cell line (RBL-2H3). Tanaka, S., Nemoto, K., Yamamura, E., Ohmura, S. and Ichikawa, A. (1997) FEBS Lett., 417, 203-207.
• Identification of multiple regulatory elements of human L-histidine decarboxylase gene. Nakagawa, S., Okaya, Y., Yatsunami, K., Tanaka, S., Ohtsu, H., Fukui, T., Watanabe, T. and Ichikawa, A. (1997) J. Biochem., 121, 935-940.
  
  【1996】
• Histidine decarboxylase expression in mouse mast cell line P815 is induced by mouse peritoneal cavity incubation. Ohtsu, H., Kuramasu, A., Suzuki, S., Igarashi, K., Ohuchi, Y., Sato, M., Tanaka, S., Nakagawa, S., Shirato, K., Yamamoto, M., Ichikawa, A. and Watanabe, T. (1996) J. Biol. Chem., 271(45), 28439-28444.
• Reg gene expression is increased in rat gastric enterochromaffin-like cells following water immersion stress. Asahara, M., Mushiake, S., Shimada, S., Fukui, H., Kinoshita, Y., Kawanami, C., Watanabe, T., Tanaka, S., Ichikawa, A., Uchiyama, Y., Narushima, Y., Takasawa, S., Okamoto, H., Tohyama, M. and Chiba, T. (1996) Gastroenterology, 111, 45-55.
  
  【1995】
• De novo synthesis and posttranslational processing of L-histidine decarboxylase in mice. Ichikawa, A., Fukui, T., Yamamoto, J., Ohgoh, M., Tanaka, S. and Funakoshi, A. (1995) Meth. Find. Clin. Pharmacol., 17(C), 5-9.
• Effect of repeated cold stress on mouse stomach histidine decarboxylase. Tanaka, S., Funakoshi, E., Kawahara, A., Nemoto, K., Fukui, T., Suzuki, T., Igarashi, K. and Ichikawa, A. (1995) Meth. Find. Clin. Pharmacol., 17(C), 25-29.
• Processing and activation of recombinant mouse mastocytoma histidine decarboxylase in the particulate fraction of Sf9 cells by porcine pancreatic elastase. Tanaka, S., Fukui, T., Yamamoto, J., Shima, Y., Kume, T., Ohgo, M. and Ichikawa, A. (1995) Biochim. Biophys. Acta, 1253, 9-12.
  
  【1993】
• Expression and characterization of recombinant mouse mastocytoma histidine decarboxylase. Yamamoto, J., Fukui, T., Suzuki, K., Tanaka, S., Yatsunami, K. and Ichikawa, A. (1993) Biochim. Biophys. Acta, 1216, 431-440.