プロフィール研究内容Home

[英文論文]

【2010

・Yamamoto, H., Koga, H., Katoh, Y., Takahashi, S., Nakayama, K., & Shin, H.-W. § (2010) Functional crosstalk between Rab14 and Rab4 through a dual effector, RUFY1/Rabip4. Mol. Biol. Cell 21, 2746-2755. (初の責任著者論文です。Highlightに選ばれました。)

【2009】

Saitoh, A.*, Shin, H.-W.*, Yamada, A., Waguri, S., & Nakayama, K. (2009) Three homologous ArfGAPs participate in COPI-mediated transport. J. Biol.Chem., 284, 13948-13957.

Nishimoto-Morita, K., Shin, H.-W., Mitsuhashi, H., Kitamura, M., Zhang, Q, Johannes, L., & Nakayama, K. (2009) Differential effects of depletion of ARL1 and ARFRP1 on membrane trafficking between the trans-Golgi network and endosomes. J. Biol. Chem., 284, 10583-10592.

Azuma, Y., Takada , M., Shin, H.-W., Kioka, N., Nakayama, K., & Ueda, K. (2009) Retroendocytosis pathway of ABCA1/apoA-I contributes to HDL formation. Genes Cells, 14, 191-204.

【2008】

Ishizaki, R., Shin, H.-W., Mitsuhashi, H. & Nakayama, K. (2008) Redundant Roles of BIG2 and BIG1, Guanine-nucleotide Exchange Factors for ARFs, in Membrane Traffic between the TGN and endosomes. Mol. Biol. Cell 19, 2650-2660.

Yanagida-Ishizaki, Y., Takei, T., Ishizaki, R., Imakagura, H., Takahashi, S., Shin, H.-W., Katoh, Y. & Nakayama, K. (2008) Receuitment of Tom1L1/Srcasm to endosomes and the midbody by Tsg101. Cell Struct. Funct. 33, 91-100

【2006】

Shiba, T., Koga, H., Shin, H.-W., Kawasaki, M., Kato, R., Nakayama, K. & Wakatsuki, S. (2006) Structural basis for Rab11-dependent membrane recruitment of FIP3/Arfophilin-1. Proc. Natl. Acad. Sci. USA, 103, 15416-15421.

Ishizaki, R., Shin, H.-W., Iguchi-Ariga, S.M.M., Ariga, H. & Nakayama, K. (2006) AMY-1 (associate of Myc-1) localization to the trans-Golgi network through interacting with BIG2, a guanine-nucleotide exchange factor for ADP-ribosylation factors. Genes Cells, 11, 949-959.

【2005】

Shin, H.-W., Kobayashi, H., Kitamura, M., Waguri, S., Suganuma, T., Uchiyama, Y. & Nakayama, K. (2005) Roles of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane trafficking. J. Cell Sci., 118, 4039-4048.

Shin, H.-W., Shinotsuka, C., & Nakayama, K., (2005) Expression of BIG2 and Analysis of its Function in Mammalian Cells. Methods Enzymol. 404, 206-215

Shin, H.-W., Hayashi, M., Christoforidis, S., Lacas-Gervais, S., Wenk, M., Modregger, J., Uttenweiler-Joseph, S., Wilm, M., Nystuen, A., Frankel, W.N., Solimena, M., De Camilli, P., & Zerial, M. (2005) An Enzymatic Cascade of Rab5 Effectors Regulates Phosphoinositide Turnover in the Endocytic Pathway. J. Cell Biol. 170, 607-618

Matsuya, S., Sakagami, H., Tohgo, A., Owada, Y., Shin, H.-W., Takeshima, H.,Nakayama, K., Kokubun, S., & Kondo, H. (2005) Cellular subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells. J. Neurochem. 93, 674-68

 

【2004】

Shin, H.-W. & Nakayama, K. (2004) Guanine Nucleotide-Exchange Factors for Arf GTPases: Their Diverse Functions in Membrane Traffic. J.Biochem. 136, 761-767

Shin, H.-W., Morinaga, N., Noda, M. & Nakayama, K. (2004) BIG2, a Guanine Nucleotide Exchange Factor for ADP-Ribosylation Factors: Its Localization to Recycling Endosomes and Implication in the Endosome Integrity. Mol. Biol. Cell, 15, 5283-5294.

Shin, H.-W. & Nakayama, K. (2004) Dual control of membrane targeting by PtdIns(4)P and ARF. Trends Biochem. Sci. 10, 513-515

Shiba, Y., Katoh, Y., Shiba, T., Yoshino, K., Takatsu, H., Kobayashi, H., Shin, H.-W., Wakatsuki, S. & Nakayama, K. (2004) GAT (GGA and Tom1) domain responsible for ubiquitin binding and ubiquitination. J. Biol. Chem., 279, 7105-7111.

【2002】

Defacque, H., Bos, E., Garvalov, B., Barret, C., Roy, C., Mangeat, P., Shin, H.-W., Rybin, V. & Griffiths, G. (2002) Phosphoinositides regulate membrane-dependent actin assembly by latex bead phagosomes. Mol. Biol. Cell 13, 1190-1202

Shiba, Y., Takatsu, H., Shin, H.-W. & Nakayama, K. (2002) gamma-Adaptin interacts directly with Rabaptin-5 through its ear domain. J. Biochem., 131, 327-336.

【2001】

Takatsu, H., Yoshino, K. & Nakayama, K. (2000) Adaptor gamma ear homology domain conserved in gamma-adaptin and GGA proteins that interact with gamma-synergin. Biochem. Biophys. Res. Commun., 271, 719-725.

【2000】

Futatsumori, M., Kasai, K., Takatsu, H., Shin, H.-W. & Nakayama, K. (2000) Identification and characterization of novel isoforms of COP I subunits. J. Biochem., 128, 793-801

【1999】

Kasai, K., Shin, H.-W., Shinotsuka, C., Murakami, K. & Nakayama, K. (1999) Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network. J. Biochem., 125, 780-789.

Shin, H.-W., Takatsu, H., Mukai, H., Munekata, E., Murakami, K.& Nakayama, K. (1999) Intermolecular and interdomain interactions of a dynamin-related GTP-binding protein, Dnm1p/Vps1p-like protein. J. Biol. Chem., 274, 2780-2785.

【1998】

Takatsu, H., Sakurai, M., Shin, H.-W., Murakami, K. & Nakayama, K. (1998) Identification and characterization of novel clathrin adaptor-related proteins. J. Biol. Chem., 273, 24693-24700.

【1997】
Shin, H.-W., Shinotsuka, C., Torii, S., Murakami, K. & Nakayama, K. (1997) Identification and subcellular localization of a novel mammalian dynamin-related protein homologous to yeast Vps1p and Dnm1p. J. Biochem., 122, 525-530.

[和文総説]

・中山和久,申惠媛 (2008) Arfファミリーの低分子量 GTPaseのメンブレントラフィックにおける役割.蛋白質核酸酵素, 53, 2058-2064.

   ・申惠媛,中山和久 (2006) ARFによるメンブレントラフィックの調節.細胞工学, 25, 1253-1257.

   ・中村暢宏、吉村信一郎、申 惠媛、中山和久 (2003) 小胞融合の選択性と小胞繋留機構−ゴルジ体を中心として 実験医学、21(14), 1947-1953

   ・中山和久、中村暢宏、申 惠媛 (2003) タンパク質の輸送と細胞内局在 わかる実験医学シリーズ;タンパク質がわかる 56-65