Publication -Review-

[Publications] [Review] [Miscellaneous]

2021

1. Arichi, N.; Ohno, H.
   Natural Product Synthesis via Palladium-Catalyzed C–H Bond Activation.
   In Handbook of CH-Functionalization, Ed. by D. Maiti, Wiley-VCH, Weinheim, in press.
   
2. L. C. Greiner, J. Matsuoka, S. Inuki, H. Ohno
   Azido-Alkynes in Gold(I)-Catalyzed Indole Syntheses.
   Chem. Rec. 21(12) 3897-3910. (2021) [PubMed]
   
3. Ohno, H.; Inuki, S.
   Nonbiomimetic total synthesis of indole alkaloids using alkyne-based strategies.
   Org. Biomol. Chem. 19(16) 3551-3568. (2021) [PubMed]
   
4. Inuki, S.; Ohno, H.
   Total Syntheses of Myriocin, Mycestericins and Sphingofungin E: Sphingosine Analogues Containing a β, β'-Dihydroxyα-Amino Acid Framework.
   Chem. Lett.50(6) 1313-1324. (2021)
   

2018

1. Ohno, H.; Inuki, S.
   Recent progress in palladium-catalyzed cascade cyclizations for natural product synthesis.
   Synthesis 50(4), 700–710 (2018).

2016

1. Oishi, S.; Fujii, N.
   Neuropeptide derivatives to regulate the reproductive axis: kisspeptin receptor (KISS1R) ligands and neurokinin-3 receptor (NK3R) ligands.
   Biopolymers 106(4) 588–597.(2016) [PubMed]

2014

1. Ohno, H.; Oishi, S.; Fujii, N.
   Gold-catalyzed atom-economical cascade reactions of alkynes for ring formation.
   J. Synth. Org. Chem. Jpn. 72(11) 1218–1227. (2014)
   
   
   
2. Ohno, H.
   Synthesis and applications of vinylaziridines and ethynylaziridines.
   Chem. Rev. 114(16) 7784–7814.(2014) [PubMed]
   
   
   
3. Ohno, H.; Chiba, H.; Inuki, S.; Oishi, S.; Fujii, N.
   The synthesis of alkaloids using a transition-metal-catalyzed intramolecular amination reaction.
   Synlett. 25(2) 179–192. (2014)
   
   
   

2013

1. Ohno, H.
   Gold-catalyzed cascade reactions of alkynes for construction of polycyclic compounds.
   Isr. J. Chem. 53(11-12) 869–882. (2013)
   
   
2. Tanaka, K.; Ohno, H.
   Intramolecular C－X bond formation between C=X or X－H and alkynes.
   Transition-metal-mediated aromatic ring construction 485–536. (2013)
   
   
3. Ohno, H.
   Recent advances in the construction of polycyclic compounds via palladium-catalyzed atom-economical cascade reactions.
   Asian J. Org. Chem. 2(1) 18–28. (2013) [PubMed]
   
   

2012

1. Oishi S, Fujii N.
   Peptide and Peptidomimetic Ligands for CXC Chemokine Receptor 4 (CXCR4)
   Org. Biomol. Chem.10(30), 5720-5731 (2012) [PubMed]
   
   
2. 竹内智起、大石真也、藤井信孝
   ケミカルバイオロジー研究を基盤にした抗癌剤の創出：KSP阻害剤の創出
   Idenshi Igaku Mook, 20 54-59 (2012)
   
   

2011

1. Popiel H. A, Burke J. R, Strittmatter W. J, Oishi S, Fujii N, Toda T, Wada K, Nagai Y.
   The aggregation inhibitor peptide QBP1 as a therapeutic molecule for the polyglutamine neurodegenerative diseases.
   J. Amino Acids. 265084 (2011)
   
   

2010

1. 大石真也、藤井信孝
   ケモカイン受容体CXCR4 とそのアンタゴニスト.
   和光純薬時報. 78(1) 2-5. (2010)
   
   

2009

1. Hyunsuk S., Oishi S., Fujii N.
   Chemokine receptor CXCR4 as a therapeutic target for neuroectodermal tumors.
   Semin. Cancer Biol. 9(2) 123-134 (2009) [PubMed]
   
   

2008

1. Tamamura H., Tsutsumi H., Nomura W., Tanaka T., Fujii N.
   A future perspective on the development of chemokine receptor CXCR4 antagonists.
   Expert Opin. Drug Discov. 3(10) 1155-1166 (2008)
   
   
2. Oishi S., Narumi T., Ohno H., Otaka A., Fujii N.
   Synthesis of highly functionalized alkene dipeptide isosteres and its application to the structure-activity relationship study on bioactive peptides.
   J. Synth. Org. Chem. Jpn. 66(9) 846-857 (2008)
   
   

2007

1. Tamamura H., Tsutsumi H., Masuno H., Fujii N.
   Development of low molecular weight CXCR4 antagonists by exploratory structural tuning of cyclic tetra- and pentapeptide-scaffolds towards the treatment of HIV infection, cancer metastasis and rheumatoid arthritis.
   Curr. Med. Chem. 14(1) 93-102 (2007)  [Link]
   
   
2. Tsutsumi H., Tanaka T., Ohashi N., Masuno H., Tamamura H., Hiramatsu K., Araki T., Ueda S., Oishi S., Fujii N.
   The therapeutic potential of the chemokine receptor CXCR4 antagonists as multi-functional agents.
   Biopolymers, 88(2) 279-289 (2007) [Link]
   
   
3. Tsutsumi H., Tamamura H., Fujii N.
   Inhibitors of the chemokine receptor CXCR4:　chemotherapy of AIDS, metastatic cancer, leukemia and rheumatoid arthritis.
   Lett. Drug Design Discov. 4(1) 20-26 (2007)  [Link]
   
   
4. 大石真也、藤井信孝
   ペプチドをリードとした創薬
   Tanpakushitsu Kakusan Koso, 52(13,zokan) 1696-1701 (2007)
   
   
5. 大石真也、藤井信孝
   ケミカルバイオロジーを基盤とするペプチド創薬
   Idenshi Igaku Mook, 8 87-91 (2007)
   
   

◇2006 [TOP]

1. Tamamura H., Tsutumi H., Fujii N.
   The chemokine receptor CXCR4 as a therapeutic target for several diseases.
   Mini Rev. Med. Chem. 6(9) 989-995 (2006)  [Link]
   
   
2. Otaka A., Fujii N.
   Development of antiviral fusion inhibiting peptides.
   Kagaku Kogyo, 57(10) 797-801 (2006)
   
   

2005

1. Tamamura H., Fujii N.
   The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis.
   Expert Opin. Ther. Targets, 9(6) 1267-1282 (2005) [Link]
   
   
2. Ohno H.
   Development of useful reactions involving tandem cyclizations based on the novel reactivities of allenic compounds.
   Chem. Pharm. Bull. 53(10) 1211-1226 (2005) [Link]
   
   
3. Fujii N., Otaka A., Tamamura H.
   Innovative platform for drug discovery based on chemical proteomics: from knowledge to controlling.
   Saibo Kogaku 24(11) 1181-1186 (2005)
   
   
4. Tamamura H., Otaka A., Fujii N.
   Development of anti-HIV agents targeting dynamic supramolecular mechanism: entry and fusion inhibitors based on CXCR4/CCR5 antagonists and gp41-C34-remodeling peptides.
   Curr. HIV Res. 3(4) 289-301 (2005) [Link]
   
   
5. Ohno H.
   アレン系化合物の新しい反応性に基づく有用反応の開発と連続環化反応への展開
   Yakugaku Zasshi 125(12) 889-926 (2005) [Link]
   
   

2004

1. Tamamura H., Fujii N.
   Two orthogonal approaches to overcome multi-drug resistant HIV-1s: development of protease inhibitors and entry inhibitors based on CXCR4 antagonists.
   Curr. Drug Targets Infec. Disord. 4(2) 103-110 (2004) [Link]
   
   
2. Otaka A., Mitsuyama E., Watanabe J., Watanabe H., Fujii N.
   Synthesis of fluorine-containing bioisosteres corresponding to phosphoamino acids and dipeptide units.
   Biopolymers, 76(2) 140-149 (2004) [Link]
   
   
3. Fujii N.
   Medicinal chemistry based on proteomics: from knowledge to controlling.
   BIO. Clinica. 19(14) 1178-1184 (2004)
   
   
4. Otaka A., Fujii N., Yamamoto N.
   Prospect of SARS drugs.
   Gendai Iryo, 36(11) 2198-2203 (2004)
   
   

2003

1. Fujii N., Nakashima H., Tamamura H.
   The therapeutic potential of CXCR4 antagonists in the treatment of HIV.
   Expert Opinion on Investigational Drugs, 12(2) 185-195 (2003) [Link]
   
   

2002

1. Fujii N.
   Genomic information-based astringent drug discovery and development.
   Biobencha, 2(5) 24-29 (2002)