Department of Analytical Chemistry,
Graduate School of Pharmaceutical Sciences, Kyoto University
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2004

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"Membrane translocation mechanism of the antimicrobial peptide buforin 2."

Satoe Kobayashi, Akinori Chikushi, Shiho Togu, Yuichi Imura, Minoru Nishida, Yoshiaki Yano, and Katsumi Matsuzaki

Biochemistry, 43, 15610-15616 (2004)


"Facile synthesis of membrane-embedded peptide utilizing lipid bilayer-assisted chemical ligation."

Akira Otaka, Satoshi Ueda, Kenji Tomita, Yoshiaki Yano, Hirokazu Tamamura, Katsumi Matsuzaki and Nobutaka Fujii

Chem. Commun., 1722-1723 (2004)


"Interaction between amyloid beta-protein aggregates and membranes."

Atsuko Kakio, Yoshiaki Yano, Denshi Takai, Yukihiro Kuroda, Osamu Matsumoto, Yasunori Kozutsumi, Katsumi Matsuzaki

J. Peptide Sci., 10, 612-621 (2004)


"Environment- and mutation-dependent aggregation behavior of Alzheimer amyloid beta-protein."

Naoki Yamamoto, Kazuhiro Hasegawa, Katsumi Matsuzaki, Hironobu Naiki, Katsuhiko Yanagisawa

J. Neurochem., 90, 62-69 (2004)


"A seed for Alzheimer amyloid in the brain."

Hideki Hayashi, Nobuyuki Kimura, Haruyasu Yamaguchi, Kazuhiro Hasegawa, Tatsuki Yokoseki, Masao Shibata, Naoki Yamamoto, Makoto Michikawa, Yasuhiro Yoshikawa, Keiji Terao, Katsumi Matsuzaki, Cynthia A. Lemere, Dennis J. Selkoe, Hironobu Naiki, Katsuhiko Yanagisawa

J. Neurosci. , 24, 4894-4902 (2004)


"Role of positional hydrophobicity in the leishmanicidal activity of magainin 2."


Esther Guerrero, José M. Saugar, Katsumi Matsuzaki, Luis Rivas

Antimicrob. Agents Chemother., 48, 2980-2986 (2004)


"Core and heterogeneity of beta2-microglobulin amyloid fibrils as revealed by H/D exchange."


Kei-ichi. Yamaguchi, Hidenori Katou, Masaru Hoshino, Kazuhiro Hasegawa, Hironobu Naiki, Yuji Goto

J. Mol. Biol., 338, 559-571 (2004)


"Increase in the conformational flexibility of beta2-microglobulin upon copper binding: a possible role for copper in dialysis-related amyloidosis."


James Villanueva, Masaru Hoshino, Hidenori Katou, József Kardos, Kazuhiro Hasegawa, Hironobu Naiki, Yuji Goto

Protein Sci., 13, 797-809 (2004)


"Protein folding by the effects of macromolecular crowding."


Nobuhiko Tokuriki, Masataka Kinjo, Shigeru Negi, Masaru Hoshino, Yuji Goto, Itaru Urabe, Tetsuya Yomo

Protein Sci., 13, 125-133 (2004)


"Sensitivity-enhanced double TROSY experiment for simultaneous measurement of one-bond 15N-1H, 15N-13C' and two-two bond 1H-13C' couplings."


Masaru Hoshino, Gottfried Otting

J. Magn. Reson., 171, 270-276 (2004)


"Conformational stability of amyloid fibrils of beta2-microglobulin probed by guanidine-hydrochloride-induced unfolding."


Takehiro Narimoto, Kazumasa Sakurai, Azusa Okamoto, Eri Chatani, Masaru Hoshino, Kazuhiro Hasegawa, Hironobu Naiki, Yuji Goto

FEBS Lett., 576, 313- 319 (2004)


"Direct observation of Abeta amyloid fibril growth and inhibition."


Tadato Ban, Masaru Hoshino, Satoshi Takahashi, Daizo Hamada, Kazuhiro Hasegawa, Hironobu Naiki, Yuji Goto

J. Mol. Biol., 344, 757-767 (2004)


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1. Antimicrobial Peptides
2. Alzheimer's Disease
3. Membrane Proteins
4. G protein Coupled Receptors
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