2022

  1. Ota R, Yamashita F: Application of machine learning techniques to the analysis and prediction of drug pharmacokinetics. J Control Release. 352, 961-969 (2022).
  2. Kurebayashi N, Murayama T, Ota R, Suzuki J, Kanemaru K, Kobayashi T, Ohno S, Horie M, Iino M, Yamashita F, Sakurai T. Cytosolic Ca2+-dependent Ca2+ release activity primarily determines the ER Ca2+ level in cells expressing the CPVT-linked mutant RYR2. J Gen Physiol. 154(9), e202112869 (2022).
  3. Sasaki Y, Tatsuoka H, Tsuda M, So K, Higuchi Y, Takayama K, Torisawa YS, Yamashita F. Intestinal permeability of drugs in Caco-2 cells cultured in microfluidic devices, Biol Pharm Bull, in press.
  4. Zhang Q, Taniguchi S, So K, Tsuda M, Higuchi Y, Hashida M, Yamashita F. CREB is a potential marker associated with drug-induced liver injury: identification and validation through transcriptome database analysis. J Toxicol Sci, in press.
  5. Chantarasrivong C, Okada R, Yamanea Y, Yang X, Higuchi Y, Konishi M, Komura N, Ando H, Yokokawa R, Yamashita F: Disposition of E-selectin-targeting liposomes in tumor spheroids with a perfusable vascular network. Drug Metab Pharmacokin, 46, 100469 (2022).
  6. Wang M, Tsuda M, Deguchi S, Higuchi Y, So K, Torisawa YS, Takayama K, Yamashita F: Application of perfluoropolyether elastomers in microfluidic drug metabolism assays. Int J Pharm, 627, 122253 (2022).

2021

  1. Deguchi S, Tsuda M, Kosugi K, Sakamoto A, Mimura N, Negoro R, Sano E, Nobe T, Maeda K, Kusuhara H, Mizuguchi H, Yamashita F, Torisawa YS, Takayama K. Usability of polydimethylsiloxane-based microfluidic devices in pharmaceutical research using human hepatocytes. ACS Biomater Sci Eng, 7(8), 3648-3657 (2021).
  2. Ota R, So K, Tsuda M, Higuchi Y, Yamashita F. Prediction of HIV drug resistance based on the 3D protein structure: Proposal of molecular field mapping. PLoS One, 16(8), e0255693 (2021).
  3. Tanaka Y, Higashihara K, Nakazawa MA, Yamashita F, Tamada Y, Okuno Y. Dynamic changes in gene-to-gene regulatory networks in response to SARS-CoV-2 infection. Sci Rep, 11(1), 11241 (2021).
  4. Sano E, Deguchi S, Matsuoka N, Tsuda M, Wang M, Kosugi K, Mori C, Yagi K, Wada A, Yamasaki S, Kawai T, Yodogawa M, Mizuguchi H, Nakazawa N, Yamashita F, Torisawa YS, Takayama K. Generation of tetrafluoroethylene-propylene elastomer-based microfluidic devices for drug toxicity and metabolism studies. ACS Omega, 6(38), 24859-24865 (2021).
  5. Haidar MK, Yamashita F, Hashida M. Minocycline hydrochloride controlled-release microsphere preparation process optimization based on the robust design method. Turk J Pharm Sci, 18(6), 752-760 (2021).

2020

  1. Nomura S, Takahashi M, Kato AH, Wada Y, Watanabe Y, Yamashita F, Mukai H. Biosorption-based 64Cu-labeling of bacteria for pharmacokinetic positron-emission tomography. Int J Pharm. 590:119950 (2020).
  2. Abdalkader R, Unga J, Maruyama K, Yamashita F, Hashida M. The Application of the in-Situ Hyperthermia Emission from Acoustic Nanodroplets for Theranostic Dual-Imaging and Antitumor Modalities. Biol Pharm Bull. 43(7):1141-1145 (2020).
  3. Tanaka Y, Tamada Y, Ikeguchi M, Yamashita F, Okuno Y. System-Based Differential Gene Network Analysis for Characterizing a Sample-Specific Subnetwork. Biomolecules. 10(2):306 (2020).
  4. Taniguchi Y, Oyama N, Fumoto S, Kinoshita H, Yamashita F, Shimizu K, Hashida M, Kawakami S. Tissue suction-mediated gene transfer to the beating heart in mice. PLoS One. 15(2):e0228203 (2020).
  5. Oyama N, Takahashi H, Kawaguchi M, Miyamoto H, Nishida K, Tsurumaru M, Nakashima M, Yamashita F, Hashida M, Kawakami S. Effects of Tissue Pressure on Transgene Expression Characteristics via Renal Local Administration Routes from Ureter or Renal Artery in the Rat Kidney. Pharmaceutics. 12(2):114 (2020).

2019

  1. Abdalkader R, Unga J, Yamashita F, Maruyama K, Hashida M. Evaluation of the Theranostic Potential of Perfluorohexane-Based Acoustic Nanodroplets. Biol Pharm Bull. 42(12):2038-2044 (2019).
  2. Feng C, Zhang H, Chen J, Wang S, Xin Y, Qu Y, Zhang Q, Ji W, Yamashita F, Rui M, Xu X. Ratiometric co-encapsulation and co-delivery of doxorubicin and paclitaxel by tumor-targeted lipodisks for combination therapy of breast cancer. Int J Pharm. 560:191-204 (2019).
  3. Rahimova N, Babazada H, Higuchi Y, Yamashita F, Hashida M. Development of mKO2 fusion proteins for real-time imaging and mechanistic investigation of the degradation kinetics of human IκBα in living cells. Biochim Biophys Acta Mol Cell Res. 1866(2):190-198 (2019).
  4. Ota R, Ishii H, Tsuda M, Higuchi Y, Yamashita F. A model-based comparative meta-analysis of the efficacy of dolutegravir-based and efavirenz-based regimens in HIV-infected patients. J Infect Chemother. 25(9):687-694 (2019).
  5. Abdalkader R, Unga J, Yamashita F, Maruyama K, Hashida M. Evaluation of the Theranostic Potential of Perfluorohexane-Based Acoustic Nanodroplets. Biol Pharm Bull. 42(12):2038-2044 (2019).

2018

  1. Babazada H, Yanamoto S, Hashida M, Yamashita F. Binding and structure- kinetic relationship analysis of selective TLR4-targeted immunosuppressive self- assembling heparin nanoparticles. Int J Pharm, 552(1-2):76-83 (2018).
  2. Matsumura K, Zouda M, Wada Y, Yamashita F, Hashida M, Watanabe Y, Mukai H. Urokinase injection-triggered clearance enhancement of a 4-arm PEG-conjugated 64Cu-bombesin analog tetramer: A novel approach for the improvement of PET imaging contrast. Int J Pharm. 545(1-2):206-214 (2018).

2017

  1. Yamashita F, Fujita A, Sasa Y, Higuchi Y, Tsuda M, Hashida M. An evolutionary search algorithm for covariate models in population pharmacokinetic analysis. J Pharm Sci, 106(9):2407-2411 (2017)
  2. Yanamoto S, Babazada H, Sakai S, Higuchi Y, Yamashita F, Hashida M. Anti-inflammatory effect of self-assembling glycol-split glycosaminoglycan-stearylamine conjugates in lipopolysaccharide-stimulated macrophages. Biol Pharm Bull, 40(4): 540-545 (2017)
  3. Baba H, Ueno Y, Hashida M, Yamashita F. Quantitative prediction of ionization effect on human skin permeability. Int J Pharm, 522(1-2): 222-233 (2017)
  4. Higashino T, Nakatsuji H, Fukuda R, Okamoto H, Imai H, Matsuda T, Tochio H, Shirakawa M, Tkachenko NV, Hashida M, Murakami T, Imahori H. Hexaphyrin as a potential theranostic dye for photothermal therapy and 19F magnetic resonance imaging. Chembiochem, in press
  5. Chantarasrivong C, Ueki A, Ohyama R, Unga J, Nakamura S, Nakanishi I, Higuchi Y, Kawakami S, Ando H, Imamura A, Ishida H, Yamashita F, Kiso M, Hashida M. Synthesis and functional characterization of novel sialyl LewisX mimic-decorated liposomes for E-selectin-mediated targeting to inflamed endothelial cells. Mol Pharm, 14(5): 1528-1537 (2017)
  6. Abdalkader R, Kawakami S, Unga J, Higuchi Y, Suzuki R, Maruyama K, Yamashita F, Hashida M. The development of mechanically formed stable nanobubbles intended for sonoporation-mediated gene transfection. Drug Deliv, 24(1): 320-327 (2017)
  7. Hatanaka W, Kawaguchi M, Sun X, Nagao Y, Ohshima H, Hashida M, Higuchi Y, Kishimura A, Katayama Y, Mori T. Use of membrane potential to achieve transmembrane modification with an artificial receptor. Bioconjug Chem, 28(2): 296-301 (2017)
  8. Ohta T, Hashida Y, Higuchi Y, Yamashita F, Hashida M. In vitro cellular gene delivery employing a novel composite material of single-walled carbon nanotubes associated with designed peptides with pegylation. J Pharm Sci, 106(3): 792-802 (2017)

2016

  1. Masuda M, Kawakami S, Wijagkanalan W, Suga T, Fuchigami Y, Yamashita F, Hashida M. Anti-MUC1 aptamer/negatively charged amino acid dendrimer conjugates for targeted delivery to human lung adenocarcinoma A549 cells. Biol Pharm Bull, 39(10): 1734-1738 (2016)
  2. Ohta T, Hashida Y, Yamashita F, Hashida M. Sustained release of mitomycin C from its conjugate with single-walled carbon nanotubes associated by pegylated peptide. Biol Pharm Bull, 39(10): 1687-1693 (2016)
  3. Morishita Y, Yoshioka Y, Takimura Y, Shimizu Y, Namba Y, Nojiri N, Ishizaka T, Takao K, Yamashita F, Takuma K, Ago Y, Nagano K, Mukai Y, Kamada H, Tsunoda S, Saito S, Matsuda T, Hashida M, Miyakawa T, Higashisaka K, Tsutsumi Y. Distribution of silver nanoparticles to breast milk and their biological effects on breast-fed offspring mice. ACS Nano, 10(9): 8180-8191 (2016)
  4. Katsumi H, Nishikawa M, Hirosaki R, Okuda T, Kawakami S, Yamashita F, Hashida M, Sakane T, Yamamoto A. Development of PEGylated cysteine-modified lysine dendrimers with multiple reduced thiols to prevent hepatic ischemia/reperfusion injury. Mol Pharm, 13(8): 2867-2873 (2016)
  5. Ose A, Toshimoto K, Ikeda K, Maeda K, Yoshida S, Yamashita F, Hashida M, Ishida T, Akiyama Y, Sugiyama Y. Development of a support vector machine-based system to predict whether a compound is a substrate of a given drug transporter using its chemical structure. J Pharm Sci, 105(7): 2222-2230 (2016)
  6. Ohta T, Hashida Y, Yamashita F, Hashida M. Development of novel drug and gene delivery carriers composed of single-walled carbon nanotubes and designed peptides with PEGylation. J Pharm Sci, 105(9): 2815-2824 (2016)
  7. Fumoto S, Taniguchi N, Ikai Y, Yoshikawa N, Miyamoto H, Sasaki H, Hashida M, Kawakami S, Nishida K. The insertion timing of PEGylated lipids to galactosylated lipoplexes is important for liver-selective transfection in mice. Gene Cell Ther, 1(1): 1-11 (2016)
  8. Suzuki R, Oda Y, Omata D, Nishiie N, Koshima R, Shiono Y, Sawaguchi Y, Unga J, Naoi T, Negishi Y, Kawakami S, Hashida M, Maruyama K. Tumor growth suppression by the combination of nanobubbles and ultrasound. Cancer Sci, 107(3): 217-223 (2016)
  9. Taniguchi Y, Kawakami S, Fuchigami Y, Oyama N, Yamashita F, Konishi S, Shimizu K, Hashida M. Optimization of renal transfection using a renal suction-mediated transfection method in mice. J Drug Target, 24(5): 450-456 (2016)

2015

  1. Baba H, Takahara J, Yamashita F, Hashida M. Modeling and prediction of solvent effect on human skin permeability using support vector regression and random forest. Pharm Res, 32(11): 3604-3617 (2015)
  2. Oda Y, Suzuki R, Mori T, Takahashi H, Natsugari H, Omata D, Unga J, Uruga H, Sugii M, Kawakami S, Higuchi Y, Yamashita F, Hashida M, Maruyama K. Development of fluorous lipid-based nanobubbles for efficiently containing perfluoropropane. Int J Pharm, 487(1-2): 64-71 (2015)
  3. Abdalkader R, Kawakami S, Unga J, Suzuki R, Maruyama K, Yamashita F, Hashida M. Evaluation of the potential of doxorubicin loaded microbubbles as a theranostic modality using a murine tumor model. Acta Biomater, 19: 112-118 (2015)
  4. Atobe T, Mori M, Yamashita F, Hashida M, Kouzuki H. Artificial neural network analysis for predicting human percutaneous absorption taking account of vehicle properties. J Toxicol Sci, 40(2): 277-294 (2015)
  5. Otani Y, Kawakami S, Mukai H, Fuchigami Y, Yamashita F, Hashida M. Long-term in vivo gene expression in mouse kidney using φC31 integrase and electroporation. J Drug Target, 23(5): 427-435 (2015)
  6. Shimizu K, Araki H, Sakata K, Tonomura W, Hashida M, Konishi S. Microfluidic devices for construction of contractile skeletal muscle microtissues. J Biosci Bioeng, 119(2): 212-216 (2015)
  7. Ueki A, Un K, Mino Y, Yoshida M, Kawakami S, Ando H, Ishida H, Yamashita F, Hashida M, Kiso M. Synthesis and evaluation of glyco-coated liposomes as drug carriers for active targeting in drug delivery systems. Carbohydr Res, 405: 78-86 (2015)

2014

  1. Babazada H, Yamashita F, Hashida M. Suppression of experimental arthritis with self-assembling glycol-split heparin nanoparticles via inhibition of TLR4-NF-κB signaling. J Control Release, 194: 295-300 (2014)
  2. Babazada H, Yamashita F, Yanamoto S, Hashida M. Self-assembling lipid modified glycol-split heparin nanoparticles suppress lipopolysaccharide-induced inflammation through TLR4-NF-κB signaling. J Control Release, 194: 332-340 (2014)
  3. Yoshida M, Kawakami S, Kono Y, Un K, Higuchi Y, Maruyama K, Yamashita F, Hashida M. Enhancement of the anti-tumor effect of DNA vaccination using an ultrasound-responsive mannose-modified gene carrier in combination with doxorubicin-encapsulated PEGylated liposomes. Int J Pharm, 475(1-2): 401-407 (2014)
  4. Nakanishi H, Higuchi Y, Yamashita F, Hashida M. Targeted gene integration using the combination of a sequence-specific DNA-binding protein and phiC31 integrase. J Biotechnol, 186: 139-147 (2014)
  5. Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M. Kidney-selective gene transfection using anionic bubble lipopolyplexes with renal ultrasound irradiation in mice. Nanomedicine, 10(8): 1829-1838 (2014)
  6. Murakami T, Nakatsuji H, Morone N, Heuser JE, Ishidate F, Hashida M, Imahori H. Mesoscopic metal nanoparticles doubly functionalized with natural and engineered lipidic dispersants for therapeutics. ACS Nano, 8(7): 7370-7376 (2014)
  7. Zhou S, Hashida Y, Kawakami S, Mihara J, Umeyama T, Imahori H, Murakami T, Yamashita F, Hashida M. Preparation of immunostimulatory single-walled carbon nanotube/CpG DNA complexes and evaluation of their potential in cancer immunotherapy. Int J Pharm, 471(1-2): 214-223 (2014)
  8. Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M. Antitumor effect of nuclear factor-κB decoy transfer by mannose-modified bubble lipoplex into macrophages in mouse malignant ascites. Cancer Sci, 105(8): 1049-1055 (2014)
  9. Yoshida M, Kawakami S, Un K, Kono Y, Higuchi Y, Yamashita F, Hashida M. Evaluation of inflammatory responses due to small interfering RNA transfer using unmodified- and mannose-modified bubble lipoplexes with ultrasound exposure in primary cultured macrophages. J Drug Target, 22(8): 732-738 (2014)
  10. Ukawa M, Akita H, Hayashi Y, Ishiba R, Tange K, Arai M, Kubo K, Higuchi Y, Shimizu K, Konishi S, Hashida M, Harashima H. Neutralized nanoparticle composed of SS-cleavable and pH-activated lipid-like material as a long-lasting and liver-specific gene delivery system. Adv Healthc Mater, 3(8): 1222-1229 (2014)
  11. Kono Y, Kawakami S, Higuchi Y, Maruyama K, Yamashita F, Hashida M. Tumour-associated macrophages targeted transfection with NF-κB decoy/mannose-modified bubble lipoplexes inhibits tumour growth in tumour-bearing mice. J Drug Target, 22(5): 439-449 (2014)
  12. Katsumi H, Nishikawa M, Nishiyama K, Hirosaki R, Nagamine N, Okamoto H, Mizuguchi H, Kusamori K, Yasui H, Yamashita F, Hashida M, Sakane T, Yamamoto A. Development of PEGylated serum albumin with multiple reduced thiols as a long-circulating scavenger of reactive oxygen species for the treatment of fulminant hepatic failure in mice. Free Radic Biol Med, 69: 318-323 (2014)
  13. Matsumura K, Sakai C, Kawakami S, Yamashita F, Hashida M. Inhibition of cancer cell growth by GRP78 siRNA lipoplex via activation of unfolded protein response. Biol Pharm Bull, 37(4): 648-653 (2014)
  14. Shimizu K, Zhang G, Kawakami S, Taniguchi Y, Hayashi K, Hashida M, Konish S. Liver suction-mediated transfection in mice using a pressure-controlled computer system. Biol Pharm Bull, 37(4): 569-575 (2014)
  15. Kurosaki T, Kawakami S, Higuchi Y, Suzuki R, Maruyama K, Sasaki H, Yamashita F, Hashida M. Development of anionic bubble lipopolyplexes for efficient and safe gene transfection with ultrasound exposure in mice. J Control Release, 176: 24-34 (2014)
  16. Hashida Y, Tanaka H, Zhou S, Kawakami S, Yamashita F, Murakami T, Umeyama T, Imahori H, Hashida M. Photothermal ablation of tumor cells using a single-walled carbon nanotube-peptide composite. J Control Release, 173: 59-66 (2014)
  17. Kono Y, Kawakami S, Higuchi Y, Yamashita F, Hashida M. In vitro evaluation of inhibitory effect of nuclear factor-kappaB activity by small interfering RNA on pro-tumor characteristics of M2-like macrophages. Biol Pharm Bull, 37(1): 137-144 (2014)