Research Outline
Contents of the Research Project
Group A01 (Chemical Communications in Biological Species)
Screening and development of bioactive natural products as chemical communication molecules by a target-based phenotypic screening approach.
Group A02 (Ligand-induced Chemical Communications)
Development of bioactive synthetic ligands as chemical communication molecules by theoretical design & synthesis and physicochemical approach.
Group A03 (Integrated Methods for Chemical Communication Analysis)
Development and application of integrated platforms for identifying chemical communication molecules and analyzing their modes of action.
Proposal with synergistic, transversal, and applied perspectives will be openly recruited for these research items.
Expected Research Achievements and Scientific Significance
This research project will establish a new scientific principle of “Molecular Sociology” in regard to chemical communications in the natural environment, which will result in the paradigm shift not only in natural product chemistry but also in chemical biology. Moreover, a new class of useful chemical tools as well as pharmaceutical and agrochemical leads will be developed, contributing greatly to human welfare in the future.
We also focus on international collaboration among interdisciplinary research fields, leading to international network development and bringing up young scientists broader views and higher expertise.
Research Key Words
Chemical Communications, Chemical Signal, Molecular Sociology, Natural Product Chemistry, Bioactive Ligand, Chemical Biology, Chemical Genomics, Chemical Ecology, Cheminformatics, Artificial Intelligence (AI), Bioinformatics