Groups & Members
-
Executive Committee | Evaluation Committee | Collaborators |
Project Groups A01 | Project Groups A02 | Project Groups A03
Recruited Groups【1st Stage：2018.03～2020.3】 A01 | A02 | A03
Recruited Groups【2nd Stage：2020.04～2020.3】 A01 | A02 | A03
Executive Committee
| Hideaki Kakeya, Ph.D. | Professor, Department of Pharmaceutical Sciences, Kyoto University |
| Hirokazu Kawagishi, Ph.D. | Professor, Research Institute of Green Science and Technology , Shizuoka University |
| Shigeki Matsunaga, Ph.D. | Professor, Graduate School of Agricultural and Life Sciences, The University of Tokyo |
| Kazuto Nishio, M.D. | Professor, Graduate School of Medicine, Kindai University |
| Kazuhiro Irie, Ph.D. | Professor, Graduate School of Agriculture, Kyoto University |
| Michio Murata, Ph.D. | Professor, Graduate School of Science, Osaka University |
| Minoru Ueda, Ph.D. | Professor, Department of Chemistry, Tohoku University |
| Motonari Uesugi, Ph.D. | Professor, Institute for Chemical Research, Kyoto University |
| Kazuya Kikuchi, Ph.D. | Professor, Graduate School of Engineering, Osaka University |
| Yasubumi Sakakibara, Ph.D. | Professor, Faculty of Science and Technology, Keio University |
| Charles Boone, Ph.D. | Team Leader, Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science |
| Hiroyuki Osada, Ph.D. | Vice-Director, RIKEN Center for Sustainable Resource Science |
Evaluation Committee
Evaluation Committee
| Teruhiko Beppu, Ph.D. | Emeritus Professor, The University of Tokyo |
| Daisuke Uemura, Ph.D. | Emeritus Professor, Nagoya University Distinguished Professor, Kanagawa University |
| Masami Hagiya, Ph.D. | Professor, School of Science, The University of Tokyo |
| Jyunji Takabayashi, Ph.D. | Professor, Center for Ecological Research, Kyoto University |
| Tohru Fukuyama, Ph.D. | Emeritus Professor, Nagoya University |
| Kin-ichi Tadano, Ph.D. | Research Advisor, Itsuu Laboratory |
Advisory members
| Minoru Isobe, Ph.D. | Emeritus Professor, Nagoya University |
| Shoichi Kusumoto, Ph.D. | Emeritus Professor, Osaka University |
| Minoru Kanehisa, Ph.D. | Professor, Institute for Chemical Research, Kyoto University |
Collaborators
| Shinichiro Sawa | Professor, Graduate School of Science and Technology |
| Makoto Ojika | Professor, Graduate School of Bioagricultural Sciences, Nagoya University |
| Hajime Watanabe | Professor, Graduate School of Engineering, Osaka University |
| Yoshinosuke Usuki | Associate Professor, Graduate School of Science, Osaka City University |
| Kei-ichiro Nemoto | Chief Researcher, Iwate Biotechnology Research Center |
| Naoki Kanoh | Professor, Hoshi University Institute of Medicinal Chemistry |
| Toshiaki Sunazuka | Professor, Kitasato University Ōmura Satoshi Memorial Institute |
| Seijiro Hosokawa | Associate Professor, Faculty of Science and Engineering, Waseda University |
Project Groups A01: Chemical Communications in Biological Species
| Name | Department | Research title |
 Hideaki Kakeya, Ph.D. (Group Head) |
Professor, Department of Pharmaceutical Sciences, Kyoto University | Investigation of chemical communication among microbes and development of useful bioactive ligands |
| http://www.pharm.kyoto-u.ac.jp/sc-molsci/indexen.html | ||
 Hirokazu Kawagishi, Ph.D. |
Professor, Research Institute of Green Science and Technology, Shizuoka University | Disclosure of chemical communication in symbiosis and parasitism involving fungi |
| http://www.agr.shizuoka.ac.jp/c/biochem/index.html | ||
 Shigeki Matsunaga, Ph.D. |
Professor, Graduate School of Agricultural and Life Sciences, The University of Tokyo | Analysis of sponge-symbiont chemical communication to facilitate cultivation of uncultivated symbionts |
| http://anpc.fs.a.u-tokyo.ac.jp/ | ||
 Kazuto Nishio, M.D. |
Professor, Graduate School of Medicine, Kindai University | Chemical communication between human and bacterial flora and its role in inflammatory bowel disease, cancer and cancer immunity |
| http://www.med.kindai.ac.jp/genom/index_en.html | ||
Project Groups A02: Ligand-induced Chemical Communications
| Name | Department | Research title |
 Kazuhiro Irie, Ph.D. (Group Head) |
Professor, Graduate School of Agriculture, Kyoto University | Unified comprehension of chemical communication by natural PKC ligands and development of new medicinal seeds |
| http://www.orgchem.kais.kyoto-u.ac.jp/ | ||
 Michio Murata, Ph.D. |
Professor, Graduate School of Science, Osaka University | Natural product ligands for elucidating the mechanism of chemical signaling through biomembrane |
| http://www.chem.sci.osaka-u.ac.jp/lab/murata/english/index.html | ||
 Minoru Ueda, Ph.D. |
Professor, Department of Chemistry, Tohoku University | Phytotoxin-mediated chemical communications between plants and microbes. |
| http://www.orgchem1.chem.tohoku.ac.jp/orgchem1/ | ||
 Motonari Uesugi, Ph.D. |
Professor, Institute for Chemical Research, Kyoto University | Chemical Signal Analysis with Synthetic Nutrient Conjugates |
| http://www.scl.kyoto-u.ac.jp/~uesugi/index.php | ||
Project Groups A03: Integrated Methods for Chemical Communication Analysis
| Name | Department | Research title |
 Kazuya Kikuchi, Ph.D. (Group Head) |
Professor, Graduate School of Engineering, Osaka University | Imaging methods for clarification of chemical communications and for function identification of biological ligands |
| http://www-molpro.mls.eng.osaka-u.ac.jp/English/indexeng/indexENG.html | ||
 Yasubumi Sakakibara, Ph.D. |
Professor, Faculty of Science and Technology, Keio University | Computational analysis of grammatical structure in chemical communication space |
| http://www.dna.bio.keio.ac.jp/index.html | ||
 Charles Boone, Ph.D. |
Team Leader, Molecular Ligand Target Research Team, RIKEN Center for Sustainable Resource Science | A chemical genomics approach for understanding chemical communication |
| http://www.riken.jp/en/research/labs/csrs/mol_ligand_targ/ | ||
 Hiroyuki Osada, Ph.D. |
Vice-Director, RIKEN Center for Sustainable Resource Science | Development of a proteomic technology platform for chemical signal analyses |
| http://www.cbrg.riken.jp/csrs/en/ | ||
Recruited Groups A01 (Chemical Communications in Biological Species)
【2nd Stage：2020.4～2022.3】
| Name | Department | Research title |
| Hideyuki Matsuura | Professor, Research Faculty of Agriculture, Hokkaido University |
Why do plants receive symbiotic fungi? Analysis of chemical communication that contributes to symbiosis system |
| https://hokudaiseibutsuyuuki.wixsite.com/natural-products | ||
| Masao Miyazaki | Associate Professor, Faculty of Agriculture, Iwate University |
Study on olfactory receptors and neuro-ciucits for the matatabi response in domestic cats |
| http://www.agr.iwate-u.ac.jp/teacher/%E5%AE%AE%E5%B4%8E%E3%80%80%E9%9B%85%E9%9B%84/ | ||
| Takashi Tsuboi | Professor, Graduate School of Arts and Sciences, The University of Tokyo |
Elucidation of chemical communication between gastrointestinal enteroendocrine cells and gut microbiota |
| http://lci.c.u-tokyo.ac.jp | ||
| Yasushi Kiyokawa | Associate Professor, Graduate School of Agricultural and Life Sciences, The University of Tokyo |
Identification of bioactive ligands that control emotions in social animals |
| http://www.vm.a.u-tokyo.ac.jp/koudou/ | ||
| Junji Hirota | Associate Professor, Tokyo Institute of Technology, School of Life Science and Technology, Department of Life Science and Technology |
Molecular mechanisms of mouse mother-pup chemical communication |
| http://www.hirota.bio.titech.ac.jp/ | ||
| Shigeru Kitani | Associate Professor, International Center for Biotechnology, Osaka University |
Clarification of chemical communication in actinomycetes for activation of cryptic natural products |
| http://hondalab.sakura.ne.jp/Molecular-M/ | ||
| Eiji Sakuradani | Professor, Industrial and Social Sciences, Graduate School of Technology, Tokushima University |
Search for new lipid ligands responsible for chemical communication between plants and microorganisms |
| http://www.bb.tokushima-u.ac.jp/faculty-member/b3/ | ||
| Kenji Kai | Associate Professor, Graduate School of Life and Environmental Sciences, Osaka Prefecture University |
Bidirectional chemical communication among microbes |
| https://kai1372.wixsite.com/npclab | ||
| Gen-ichiro Arimura | Professor, Faculty of Industrial Science and Technology, Tokyo University of Science |
Herbivore elicitor reception system in plants |
| http://www.rs.tus.ac.jp/garimura/members/index.html | ||
| Taisuke Seike | Assistant Professor, Graduate School of Information Science and Technology, Osaka university |
Elucidation of the mechanisms of asymmetric pheromonal communication in yeast |
| http://www-symbio.ist.osaka-u.ac.jp/index.html | ||
Recruited Groups A02 (Ligand-induced Chemical Communications)
【2nd Stage：2020.4～2022.3】
| Name | Department | Research title |
| Kenji Monde | Professor, Faculty of Advanced Life Science, Hokkaido University |
Mechanistic studies of obesity suppression effect of malabaricones isolated from a Malaysian fruit toward drug discovery |
| http://altair.sci.hokudai.ac.jp/infchb/http://altair.sci.hokudai.ac.jp/infchb/ | ||
| Satoshi Ichikawa | Professor, Graduate School of Pharmaceutical Sciences, Hokkaido University |
Modulation of chemical communication based on MraY inhibitory natural products and their application to drug lead discovery |
| https://japanese-apricot.pharm.hokudai.ac.jp/gouseiiyaku/en/index.php | ||
| Ryuichi Sakai | Professor, Graduate School and Faculty of Fisheries Sciences, Hokkaido University |
Multiomics approach to reveal chemical communication of tunicates |
| http://reseachmap.jp/sbor5552 | ||
| Hirokazu Arimoto | Professor, Graduate School of Life Sciences, Tohoku University |
Development of new molecules from low molecular weight ligands |
| https://www.lifesci.tohoku.ac.jp/en/research/fields/laboratory.html?id=7811 | ||
| Noriki Kutsumura | Professor, International Institute for Integrative Sleep Medicine (WPI-IIIS), University of Tsukuba |
Elucidation of novel itch-transmission pathway and development of seeds for pruritus treatment |
| http://nagase.wpi-iiis.tsukuba.ac.jp/ | ||
| Hideo Kigoshi | Vice-President and Director, Professor, Faculty of Pure and Applied Science, Tsukuba University |
Study of chemical communication between marine natural products and cytoskeleton |
| http://www.chem.tsukuba.ac.jp/kigoshi/e/frame_e.html | ||
| Kenjiro Hanaoka | Professor, Faculty of Pharmacy and Graduate School of Pharmaceutical Sciences, Keio University |
Screening/development of inhibitors for reactive sulfur species-producing enzymes by utilizing fluorescent probes and their functional analysis |
| http://www.pha.keio.ac.jp/research/acdd/index.html | ||
| Junko Ohkanda | Professor, Academic Assembly, Institute of Agriculture, Shinshu University |
Elucidation and controlling of chemical signals regulated by 14-3-3 proteins |
| http://www.shinshu-u.ac.jp/faculty/agriculture/lab/johkanda/index.html | ||
| Masaki Kita | Professor, Graduate School of Bioagricultural Sciences, Nagoya University |
Chemical communication on the mammalian venom |
| http://www.agr.nagoya-u.ac.jp/~chembio/index.html | ||
| Atsuo Nakazaki | Professor, Department of Chemistry and Biological Sciences, Iwate University |
Development of unnatural analogues of cardiac steroids for understanding attraction responses of invasive species and controlling its populations |
| http://univdb.iwate-u.ac.jp/html/100000069_en.html | ||
| Shinsuke Inuki | Assistant Professor, Graduate School of Pharmaceutical Sciences, Kyoto University |
Development of chemical tools for elucidating chemical communications in mucosal immunity |
| http://www.pharm.kyoto-u.ac.jp//seizo/index_en.html | ||
| Atsushi Shimoyama | Assistant Professor, Graduate School of Science, Osaka University |
Elucidation of host-bacterial chemical ecology mediated by lipopolysaccharide and development of vaccine adjuvants |
| http://www.chem.sci.osaka-u.ac.jp/lab/fukase/ | ||
| Atsuko Yamashita | Professor, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University |
Structural biology of perception mechanisms of chemical signals by taste receptor type 1 |
| http://www.pharm.okayama-u.ac.jp/lab/a_yama/Structure/English.html | ||
| Mitsuru Shindo | Professor, Institute for Materials Chemistry and Engineering, Kyushu University |
Plant chemical communication molecules derived from allelochemicals |
| https://shindo-kano-lab.weebly.com/english.html | ||
| Hideo Takahashi | Professor, Graduate School of Medical Life Science, Yokohama City University |
Elucidation of intramolecular network and allosteric regulation mechanism of receptors in chemical signal transduction |
| http://www.tsurumi.yokohama-cu.ac.jp/fsb/takahashi/index_e.html | ||
Recruited Groups A03 (Integrated Methods for Chemical Communication Analysis)
【2nd Stage：2020.4～2022.3】
| Name | Department | Research title |
| Kazumitsu Onizuka | Associate Professor, Institute of Multidisciplinary Research for Advanced Materials, Tohoku University |
Expansion of massive analysis of RNA-small molecule chemical signal for RNA-targeted drug discovery |
| http://www2.tagen.tohoku.ac.jp/lab/nagatsugi/html/ | ||
| Kazuki Nagayasu | Assistant Professor, Graduate School of Pharmaceutical Sciences, Kyoto University |
Development of prediction tools for therapeutic and adverse effects in human from chemical structures of small to medium-sized molecules |
| http://www.pharm.kyoto-u.ac.jp/channel/ | ||
| Mitsuru Hattori | Assistant Professor, Nagai Laboratory, ISIR, Osaka University |
Establishment of a ligand evaluation system in living organisms using a multi-scale bioluminescence indicator |
| https://www.sanken.osaka-u.ac.jp/labs/bse/ | ||
| Nobuaki Matsumori | Professor, Graduate School of Science, Kyushu University |
Screening of lipid-recognizing natural ligands for elucidation of lipid-related chemical communications |
| http://www.scc.kyushu-u.ac.jp/BioanalChem/ | ||
| Hiroyuki Seimiya | Chief, Division of Molecular Biotherapy, Cancer Chemotherapy Center, Japanese Foundation for Cancer Research |
Elucidating the functions of quadruplex nucleic acids by integrative molecular profiling of chemical signals |
| https://www.jfcr.or.jp/chemotherapy/department/molecular_biotherapy/index.html | ||
| Hiroaki Saito | Associate Professor, Faculty of Pharmaceutical Sciences, Hokuriku University |
In sillico molecular degisn for chemical communication molecules bind to membrane |
| https://researchmap.jp/hiroaki_saito | ||
| Ken Matsumoto | Senior Research Scientist, RIKEN Center for Sustainable Resource Science (CSRS) Chemical Genomics Research Group |
Mechanism of action studies of bioactive molecular ligands in human cultured cells |
| http://www2.riken.jp/SPD/CG/index.html | ||
Recruited Groups A01 (Chemical Communications in Biological Species)
【1st Stage：2018.4～2020.3】
| Name | Department | Research title |
| Masao Miyazaki | Associate Professor, Faculty of Agriculture, Iwate University |
Studies on molecular and physiological mechanisms of the Matatabi response in the domestic cat |
| http://news7a1.atm.iwate-u.ac.jp/cgi-bin/list/list.cgi?id=136 | ||
| Takashi Tsuboi | Professor, Graduate School of Arts and Sciences, The University of Tokyo |
Microbial regulation of hormone secretion from enteroendocrine cells |
| http://lci.c.u-tokyo.ac.jp | ||
| Hidemitsu Nakamura | Assistant Professor, Graduate School of Agricultural and Life Sciences, The University of Tokyo |
Elucidation of rhizosphere chemical communications using selective regulators of strigolactone functions |
| http://pgr.ch.a.u-tokyo.ac.jp/ | ||
| Junji Hirota | Associate Professor, Center for Biological Resources and Informatics, Tokyo Institute of Technology |
Molecular mechanisms of mouse mother-pup chemical communication |
| http://www.hirota.bio.titech.ac.jp/ | ||
| Makoto Ojika | Professor, Graduate School of Bioagricultural Sciences, Nagoya University |
Mechanism and application of host chemical components that inhibit reproduction of plant pathogens |
| http://bioactnagoya.wixsite.com/bioact-web-page | ||
| Shigeru Kitani | Associate Professor, International Center for Biotechnology, Osaka University |
Activation of cryptic natural products via chemical communication in actinomycetes |
| http://www.nihiralab.sakura.ne.jp/english/index.html | ||
| Hajime Watanabe | Professor, Graduate School of Engineering, Osaka University |
Chemical communication for selection of reproduction strategy |
| http://www.sci.osaka-cu.ac.jp/chem/orc/index_en.html | ||
| Eiji Sakuradani | Professor, Faculty of Biosience and Bioindustry, Tokushima University |
Research on physiologically active lipid ligands produced by Fusarium filamentous fungi |
| http://www.bb.tokushima-u.ac.jp/faculty-member/b3/ | ||
| Yoshinosuke Usuki | Associate Professor, Graduate School of Science, Osaka City University |
Exploration into chemical communication involved in biological phenomena of ciliates |
| http://www.sci.osaka-cu.ac.jp/chem/orc/index_en.html | ||
| Kenji Kai | Lecturer, Graduate School of Life and Environmental Sciences, Osaka Prefecture University |
Bidirectional chemical communication between bacteria and fungi |
| https://kai1372.wixsite.com/npclab | ||
| Gen-ichiro Arimura | Associate Professor, Faculty of Industrial Science and Technology, Tokyo University of Science |
Molecular mechanisms underlying plant recognition system for herbivore signals |
| http://www.rs.tus.ac.jp/garimura/members/index.html | ||
| Kei-ichiro Nemoto | Chief Researcher, , Iwate Biotechnology Research Center |
Molecular mechanism of allelopathic effects of genistein targeting plant tyrosine protein kinase |
| http://en.ibrc.or.jp/ | ||
| Yoshikage Muroi | Associate Professor, Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine |
Regulation of maternal behavior by chemical communications |
| http://tech.obihiro.ac.jp/~bchikumuroi/bchikumuroiToppageenglish.html | ||
Recruited Groups A02 (Ligand-induced Chemical Communications)
【1st Stage：2018.4～2020.3】
| Name | Department | Research title |
| Satoshi Ichikawa | Professor, Graduate School of Pharmaceutical Sciences, Hokkaido University |
Elucidation of P.aeruginosa-selective chemical communication molecule and its medicinal application |
| https://japanese-apricot.pharm.hokudai.ac.jp/gouseiiyaku/en/index.php | ||
| Ryuichi Sakai | Professor, Graduate School of Fisheries Sciences, Hokkaido University |
Marine polycations and their roles in chemical communication |
| http://www2.fish.hokudai.ac.jp/faculty-member/sakai-ryuichi | ||
| Naoki Kanoh | Associate Professor, Graduate School of Pharmaceutical Sciences, Tohoku University |
Chemical signaling analysis of membrane-binding natural products using synthetic probes |
| http://www.pharm.tohoku.ac.jp/~gousei/synthetic/index.html | ||
| Hirokazu Arimoto | Professor, Graduate School of Life Sciences, Tohoku University |
Improvement of natural product functions |
| https://www.lifesci.tohoku.ac.jp/en/research/fields/laboratory.html?id=7811 | ||
| Hideo Kigoshi | Vice-President and Director, Tsukuba University |
Study on chemical communication of marine natural products and cytoskeletons |
| http://www.chem.tsukuba.ac.jp/kigoshi/e/frame_e.html | ||
| Kenjiro Hanaoka | Associate Professor, Graduate School of Pharmaceutical Sciences, The University of Tokyo |
Identification and development of inhibitors for reactive sulfur-generating enzymes by utilizing fluorescent probe |
| http://www.f.u-tokyo.ac.jp/~taisha/en/ | ||
| Masaki Kita | Professor, Graduate School of Bioagricultural Sciences, Nagoya University |
Chemical communication of venomous mammals |
| https://mkita64.wixsite.com/mysite-en | ||
| Shinsuke Inuki | Assistant Professor, Graduate School of Pharmaceutical Sciences, Kyoto University |
Development of chemical tools for understanding and modulating mucosal immunity |
| http://www.pharm.kyoto-u.ac.jp//seizo/index_en.html | ||
| Atsushi Shimoyama | Assistant Professor, Graduate School of Science, Osaka University |
Elucidation of host-symbiotic bacterial chemical communications mediated by lipopolysaccharide |
| http://www.chem.sci.osaka-u.ac.jp/lab/fukase/ | ||
| Atsuko Yamashita | Professor, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University |
Structural study of chemical communications through molecular interaction between T1r taste receptors and taste substances |
| http://www.pharm.okayama-u.ac.jp/lab/a_yama/Structure/English.html | ||
| Mitsuru Shindo | Professor, Institute for Materials Chemistry and Engineering, Kyushu University |
Synthesis of chemical communication tools for elucidation of allelopathy |
| https://shindo-kano-lab.weebly.com/english.html | ||
| Hideo Takahashi | Professor, Graduate School of Medical Life Science, Yokohama City University |
Analysis of structural and dynamical aspects of allosteric regulation in chemical communications |
| http://www.tsurumi.yokohama-cu.ac.jp/fsb/takahashi/index_e.html | ||
| Toshiaki Sunazuka | Professor, Kitasato Institute for Life Sciences, Kitasato University |
Creation of chemical tools and pharmaceuticals leads using Ōmura natural products |
| http://seibutuyuuki.sakura.ne.jp/HOMEeng.html | ||
| Seijiro Hosokawa | Associate Professor, Faculty of Science and Engineering, Waseda University |
Chemistry and biology of cell wall lipids of Mycobacterium tuberculosis |
| http://www.waseda.jp/sem-hosokawalab/ | ||
Recruited Groups A03 (Integrated Methods for Chemical Communication Analysis)
【1st Stage：2018.4～2020.3】
| Name | Department | Research title |
| Toshiyuki Kowada | Assistant Professor, Institute of Multidisciplinary Research for Advanced Materials, Tohoku University |
Creation of light-switchable protein degradation system |
| http://www2.tagen.tohoku.ac.jp/lab/mizukami/ | ||
| Shuji Kaneko | Professor, Department of Pharmaceutical Sciences, Kyoto University |
A platform for predicting pharmacological actions of chemical compounds |
| http://www.pharm.kyoto-u.ac.jp/channel/en/index.html | ||
| Hiroaki Iwata | Assistant Professor, Graduate School of Medicine, Kyoto University |
Development of fast search method for druggable pocket structure using optimization algorithm |
| http://clinfo.med.kyoto-u.ac.jp/en/?doing_wp_cron=1536732291.2083609104156494140625 | ||
| Kengo Morohashi | Associate Professor, Faculty of Science and Technology, Tokyo University of Science |
Regulation of biological functions by using the ultrahigh sensitive detection tools for protein-metabolite interaction |
| https://www.rs.tus.ac.jp/morohashi/english/index.html | ||
| Hiroyuki Seimiya | Chief, Division of Molecular Biotherapy, Cancer Chemotherapy Center Japanese Foundation for Cancer Research |
Integrative functional analysis of G-quadruplex nucleic acids by utilizing natural and synthetic chemical tool molecules |
| https://www.jfcr.or.jp/english/chemotherapy/department/molecular_biotherapy/index.html | ||
| Hiroaki Saito | Research Scientist, RIKEN Center for Biosystems Dynamics Research |
in silico molecular design by means of deep learning and molecular simulation |
| https://www.bdr.riken.jp/en/research/labs/taiji-m-computational/index.html | ||