2015年2月現在


【原著論文】 【総説・著書】 【国際学会】 【国内学会】 【シンポジウム・講演】


原著論文 20132012201120102009200820072006200520042003200220012000以前

2015年

Dogishi K, Kodera M, Oyama S, Shirakawa H, Nakagawa T*, Kaneko S: Long-lasting pain-related behaviors in mouse chronic cystitis model induced by a single intravesical injection of hydrogen peroxide. J Pharmacol Sci, 129, 244-246 (2015)

Miyanohara J, Shirakawa H*, Sanpei K, Nakagawa T, Kaneko S: A pathophysiological role of TRPV1 in ischemic injury after transient focal cerebral ischemia in mice. Biochem Biophys Res Commun, 467: 478-483 (2015)

Koyama S, Omura T*, Yonezawa A, Imai S, Nakagawa S, Nakagawa T, Yano Y, Matsubara K: Gefitinib and erlotinib lead to phosphorylation of eukaryotic initiation factor 2α independent of epidermal growth factor receptor in A549 Cells. PLOS ONE, 10: e0136176 (2015)

Imoto Y, Kira T, Sukeno M, Nishitani N, Nagayasu K, Nakagawa T, Kaneko S, Kobayashi K, Segi-Nishida E*: Role of the 5-HT4 receptor in chronic fluoxetine treatment-induced neurogenic activity and granule cell dematuration in the dentate gyrus. Mol Brain, 8: 29 (2015)

Miyake T, Shirakawa H*, Nakagawa T, Kaneko S: Activation of mitochondrial transient receptor potential vanilloid 1 channel contributes to microglial migration. Glia, 63: 1870-1882 (2015)

Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T*, Kaneko S: Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT6 receptors in the dorsal raphe nucleus. Neuropharmacology, 95: 261-268 (2015)

Asaoka N, Nagayasu K, Nishitani N, Yamashiro M, Shirakawa H, Nakagawa T*, Kaneko S: Inhibition of histone deacetylases enhances the function of serotoninergic neurons in organotypic raphe slice cultures. Neurosci Lett, 593: 72-77 (2015)

So K, Haraguchi K, Asakura K, Isami K, Sakimoto S, Shirakawa H, Mori Y, Nakagawa T*, Kaneko S: Involvement of TRPM2 in a wide range of inflammatory and neuropathic pain mouse models. J Pharmacol Sci, 127: 237-243 (2015)

 

2014年

Nakagawa S*, Omura T, Yonezawa A, Yano I, Nakagawa T, Matsubara K: Extracellular nucleotides from dying cells act as molecular signals to promote wound repair in renal tubular injury. Am J Physiol Renal Physiol, 307: F1404-F1411 (2014)

Kobori T, Fujiwara S, Miyagi K, Harada S, Nakamoto K, Nakagawa T, Takahashi H, Narita M, Tokuyama S*: Involvement of moesin in the development of morphine analgesic tolerance through P-glycoprotein at the blood–brain barrier. Drug Metabol Pharmacokinet, 29: 482-489 (2014)

Nishitani N, Nagayasu K, Asaoka N, Yamashiro M, Shirakawa H, Nakagawa T*, Kaneko S: Raphe AMPA receptors and nicotinic acetylcholine receptors mediate ketamine-induced serotonin release in the rat prefrontal cortex. Int J Neuropsychopharmacol, 17: 1321-1326 (2014)

Zhao M, Nakamura S, Miyake T, So K, Shirakawa H, Tokuyama S, Narita M, Nakagawa T*, Kaneko S: Pharmacological characterization of standard analgesics on oxaliplatin-induced acute cold hypersensitivity in mice. J Pharmacol Sci, 124: 514-517 (2014)

Miyake T, Shirakawa H, Kusano A, Sakimoto S, Konno M, Nakagawa T, Mori Y, Kaneko S*: TRPM2 contributes to LPS/IFNγ-induced production of nitric oxide via the p38/JNK pathway in microglia. Biochem Biophys Res Commun, 444: 212-217 (2014)

Sakakiyama M, Maeda S, Isami K, Asakura K, So K, Shirakawa H, Nakagawa T*, Kaneko S: Preventive and alleviative effect of tramadol on neuropathic pain in rats: roles of α2-adrenoceptors and spinal astrocytes. J Pharmacol Sci, 124: 244-257 (2014)

 

2013年

Nagayasu K, Kitaichi M, Nishitani N, Asaoka N, Shirakawa H, Nakagawa T*, Kaneko S: Chronic effects of antidepressants on serotonin release in rat raphe slice cultures: high potency of milnacipran in the augmentation of serotonin release. Int J Neuropsychopharmacol, 16: 2295-2306 (2013)

Isami K, Haraguchi K, So K, Maeda S, Asakura K, Shirakawa H, Mori Y, Nakagawa T*, Kaneko S: Involvement of TRPM2 in peripheral nerve injury-induced infiltration of peripheral immune cells into the spinal cord in mouse neuropathic pain model. PLOS ONE, 8: e66410 (2013)

Munakata M, Shirakawa H, Nagayasu K, Miyanohara J, Miyake T, Nakagawa T, Katsuki H, Kaneko S*: The TRPC3 inhibitor Pyr3 improves outcomes and attenuates astrogliosis after intracerebral hemorrhage in mice. Stroke, 44: 1981-1987 (2013)

Homan T, Tsuzuki T, Dogishi K, Shirakawa H, Oyama T, Nakagawa T, Kaneko S*: A novel mouse model of chronic inflammatory and overactive bladder by a single intravesical injection of hydrogen peroxide. J Pharmacol Sci, 121: 327-337 (2013)

Sakai H, Sagara A, Matsumoto K, Hasegawa S, Sato K, Nishizaki M, Shoji T, Horie S, Nakagawa T, Tokuyama S, Narita M*: 5-Fluorouracil induces diarrhea with changes in the expression of inflammatory cytokines and aquaporins in mouse intestines. PLOS ONE, 8: e54788 (2013)

 

2012年

Nakagawa T*, Nagayasu K, Nishitani N, Shirakawa H, Sekiguchi K, Ikarashi Y, Kase Y, Kaneko S: Yokukansan inhibits morphine tolerance and physical dependence in mice: the role of α2a-adrenoceptor. Neuroscience 227: 336-349 (2012)

Zhao M, Isami K, Nakamura S, Shirakawa H, Nakagawa T*, Kaneko S: Acute cold hypersensitivity characteristically induced by oxaliplatin is caused by the enhanced responsiveness of TRPA1 in mice. Mol Pain 8: 55 (2012)

Haraguchi K, Kawamoto A, Isami K, Maeda S, Kusano A, Asakura K, Shirakawa H, Mori Y, Nakagawa T*, Kaneko S: TRPM2 contributes to inflammatory and neuropathic pain through the aggravation of pronociceptive inflammatory responses in mice. J Neurosci 32: 3931-3941 (2012)

Konno M, Shirakawa H, Iida S, Sakimoto S, Matsutani I, Miyake T, Kageyama K, Nakagawa T, Shibasaki K, Kaneko S*: Stimulation of transient receptor potential vanilloid 4 channel suppresses abnormal activation of microglia induced by lipopolysaccharide. Glia 60: 761-770 (2012)

Konno M, Shirakawa H, Miyake T, Sakimoto S, Nakagawa T, Kaneko S*: Calumin, a Ca2+-binding protein on the endoplasmic reticulum, alters the ion permeability of Ca2+-activated Ca2+ release (CRAC) channels. Biochem Biophys Res Commun 417: 784-789 (2012)

2011年

Ibi M, Matsuno K, Matsumoto M, Sasaki M, Nakagawa T, Katsuyama M, Iwata K, Zhang J, Kaneko S, Yabe-Nishimura C*: Involvement of NOX1/NADPH oxidase in morphine-induced analgesia and tolerance. J Neurosci 31: 18094-18103 (2011)

Nakagawa T*, Suzuki Y, Nagayasu K, Kitaichi M, Shirakawa H, Kaneko S: Repeated exposure to methamphetamine, cocaine or morphine induces augmentation of dopamine release in rat mesocorticolimbic slice co-cultures. PLOS ONE 6(9): e24865 (2011)

2010年

Deyama S, Takishita A, Tanimoto S, Ide S, Nakagawa T, Satoh M, Minami M*: Roles of β- and α2-adrenoceptors within the central nucleus of the amygdala in the visceral pain-induced aversion in rats. J Pharmacol Sci 114: 123-126 (2010)

Shirakawa H, Sakimoto S, Nakao K, Sugishita A, Konno M, Iida S, Kusano A, Hashimoto E, Nakagawa T, Kaneko S*: TRPC3 Mediates thrombin-induced astrocyte activation and upregulates its own expression in rat cortical astrocytes. J Neurosci 30: 13116-13129 (2010)

Nagayasu K, Yatani Y, Kitaichi M, Kitagawa Y, Shirakawa H, Nakagawa T*, Kaneko S: Utility of organotypic raphe slice cultures to investigate the effects of sustained exposure to selective serotonin reuptake inhibitors on serotonin release. Br J Pharmacol 161: 1527-1541 (2010)

Nagayasu K, Kitaichi M, Shirakawa H, Nakagawa T*, Kaneko S: Sustained exposure to 3,4-methylenedioxymethamphetamine induces the augmentation of exocytotic serotonin release in rat organotypic raphe slice cultures. J Pharmacol Sci 113: 197-201 (2010)

2009年

Deyama S, Katayama T, Kondoh N, Nakagawa T, Kaneko S, Yamaguchi T, Yoshioka M, Minami M*: Role of enhanced noradrenergic transmission within the ventral bed nucleus of the stria terminalis in visceral pain-induced aversion in rats. Behav Brain Res 197: 279-283 (2009)

2008年

Maeda S, Kawamoto A, Yatani Y, Shirakawa H, Nakagawa T*, Kaneko S: Gene transfer of GLT-1, a glial glutamate transporter, into the spinal cord by recombinant adenovirus attenuates inflammatory and neuropathic pain in rats. Mol Pain 4: 65 (2008)

Shirakawa H, Yamaoka T, Sanpei K, Sasaoka H, Nakagawa T, Kaneko S*: TRPV1 stimulation triggers apoptotic cell death of rat cortical neurons. Biochem Biophys Res Commun, 377: 1211-1215 (2008)

Nakagawa T*, Otsubo Y, Yatani Y, Shirakawa H, Kaneko S: Mechanisms of substrate transport-induced clustering of a glial glutamate transporter GLT-1 in astroglial-neuronal cultures. Eur J Neurosci 28: 1719-1730 (2008)

Ibi M, Matsuno K, Shiba D, Katsuyama M, Iwara K, Kakehi T, Nakagawa T, Sango K, Shirai Y, Yokoyama T, Kaneko S, Saito N, Yabe-Nishimura C*: Ractive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain. J Neurosci 28: 9486-9494 (2008)

Deyama S, Katayama T, Nakagawa T, Kaneko S, Yamaguchi T, Yoshioka M, Minami M*: Activation of the β-adrenoceptor-protein kinase A signaling pathway within the ventral bed nucleus of the stria terminalis mediates the negative affective component of pain in rats. J Neurosci 28: 7728-7736 (2008)

Higuchi M, Suzuki Y, Yatani Y, Kitagawa Y, Nagayasu K, Shirakawa H, Nakagawa T*, Kaneko S: Augmentation of serotonin release by sustained exposure to 3,4-methylenedioxymethamphetamine and methamphetamine in rat organotypic mesencephalic slice cultures containing raphe serotonergic neurons. J Neurochem 106: 2410-2420 (2008).

Nakagawa T*, Wakamatsu K, Maeda S, Shirakawa H, Kaneko S: Differential contribution of spinal mitogen-activated protein kinases to the phase of long-lasting allodynia evoked by intrathecal administration of ATP in rats. Biol Pharm Bull 31: 1164-1168 (2008)

Kume T, Kawato Y, Osakada F, Izumi Y, Katsuki H, Nakagawa T, Kaneko S, Niidome T, Takada-Takatori Y, Akaike A*: Dibutyryl cyclic AMP induces differentiation of human neuroblastoma SH-SY5Y cells into a noradrenergic phenotype. Neurosci Lett 443: 199-203 (2008)

Nakao K, Shirakawa H, Sugishita A, Matsutani I, Niidome T, Nakagawa T, Kaneko S*: Ca2+ mobilization mediated by transient receptor potential canonical 3 is associated with thrombin-induced morphological changes of 1321N1 human astrocytoma cells. J Neurosci Res 86: 2722-2732 (2008)

2007年

Yamauchi Y, Izumi T, Unemura K, Uenishi Y, Nakagawa T, Kaneko S*: Acceleration of serotonin transporter transport-associated current by 3,4-methylenedioxymethanphetamine (MDMA) under acidic conditions. Neurosci Lett 428: 72-76 (2007)

Tanaka K, Shirakawa H, Okada K, Konno M, Nakagawa T, Serikawa T, Kaneko S*: Increased Ca2+ channel currents in cerebellar Purkinje cells of the ataxic groggy rat. Neurosci Lett 426: 75-80 (2007)

Deyama S, Yamamoto J, Machida T, Tanimoto S, Nakagawa T, Kaneko S, Satoh M, Minami M*: Inhibition of glutamatergic transmission by morphine in the basolateral amygdaloid nucleus reduces pain-induced aversion. Neurosci Res 59: 199-204 (2007)

Nakagawa T*, Wakamatsu K, Zhang N, Maeda S, Minami M, Satoh M, Kaneko S: Intrathecal administration of ATP produces long-lasting allodynia in rats: differential mechanisms in the phase of the induction and maintenance. Neuroscience 147: 445-455 (2007)

Deyama S, Nakagawa T, Kaneko S, Uehara T, Minami M*: Involvement of the bed nucleus of the stria terminalis in the negative affective component of visceral and somatic pain in rats. Behav Brain Res 176: 367-371 (2007)

Shimamoto K*, Otsubo Y, Shigeri Y, Yasuda-Kamatani Y, Satoh M, Kaneko S, Nakagawa T: Characterization of the tritium-labeled analog of L-threo-β-benzyloxyaspartate binding to glutamate transporters. Mol Pharmacol 71: 294-302 (2007)

2006年

Fukui M, Nakagawa T*, Minami M, Satoh M, Kaneko S: Inhibitory role of supraspinal P2X3/P2X2/3 subtypes on nociception in rats. Mol Pain 2: 19 (2006)

2005年

Fujio M, Nakagawa T*, Suzuki Y, Satoh M, Kaneko S: Facilitative effect of a glutamate transporter inhibitor (2S,3S)-3-{3-[4-(trifluoromethyl)benzoylamino]benzyloxy}aspartate on the expression of methamphetamine-induced behavioral sensitization in rats. J Pharmacol Sci 99, 415-418 (2005)

Fujio M, Nakagawa T*, Sekiya Y, Ozawa T, Suzuki Y, Minami M, Satoh M, Kaneko S: Gene transfer of GLT-1, a glutamate transporter, into the nucleus accumbens shell attenuates methamphetamine- and morphine-induced conditioned place preference in rats. Eur J Neurosci 22: 2744-2754 (2005)

Nakagawa T*, Yamamoto R, Fujio M, Suzuki Y, Minami M, Satoh M, Kaneko S: Involvement of the bed nucleus of the stria terminalis activated by the central nucleus of the amygdala in the negative affective component of morphine withdrawal in rats. Neuroscience 134: 9-19 (2005)

Nakagawa T*, Fujio M, Ozawa T, Minami M, Satoh M: Effect of MS-153, a glutamate transporter activator, on the conditioned rewarding effects of morphine, methamphetamine and cocaine in mice. Behav Brain Res 156: 233-239 (2005)

2004年

Tanaka T, Minami M, Nakagawa T, Satoh M: Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain: possible involvement in the development of neuropathic pain. Neurosci Res 48: 463-469 (2004)

Fukui M, Takishita A, Zhang N, Nakagawa T, Minami M, Satoh M: Involvement of locus coeruleus noradrenergic neurons in supraspinal antinociception by a,b-methylene-ATP in rats. J Pharmacol Sci 94: 153-160 (2004)

Sekiya Y, Nakagawa T, Ozawa T, Minami M, Satoh M: Facilitation of morphine withdrawal symptoms and morphine-induced conditioned place preference by a glutamate transporter inhibitor DL-threo-b-benzyloxyaspartate in rats. Eur J Pharmacol 485: 201-210 (2004)

Ozawa T, Nakagawa T, Sekiya Y, Minami M, Satoh, M: Effect of gene transfer of GLT-1, a glutamate transporter, into the locus coeruleus by recombinant adenoviruses on morphine physical dependence in rats. Eur J Neurosci 19: 221-226 (2004)

2003年

Tanimoto S, Nakagawa T, Yamauchi Y, Minami M, Satoh M: Differential contributions of the basolateral and central nuclei of the amygdala in the negative affective component of chemical somatic and visceral pains in rats. Eur J Neurosci 18: 2343-2350 (2003)

Nakagawa T, Katsuya A, Tanimoto S, Yamamoto J, Yamauchi Y, Minami M, Satoh M: Differential patterns of c-fos mRNA expression in the amygdaloid nuclei induced by chemical somatic and visceral noxious stimuli in rats. Neurosci Lett 344: 197-200 (2003)

Watanabe T, Nakagawa T, Yamamoto R, Maeda A, Minami M, Satoh M: Involvement of noradrenergic system within the central nucleus of the amygdala in naloxone-precipitated morphine withdrawal-induced conditioned place aversion in rats. Psychopharmacology 170: 80-88 (2003)

2002年

Watanabe T, Yamamoto R, Maeda A, Nakagawa T, Minami M, Satoh M: Effects of excitotoxic lesions of the central or basolateral nucleus of the amygdala on naloxone-precipitated withdrawal-induced conditioned place aversion in morphine-dependent rats. Brain Res 958: 423-428 (2002)

Okada M, Nakagawa T, Minami M, Satoh M: Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats. J Pharmacol Exp Ther 303: 66-73 (2002)

Yamakuni H, Kawaguchi N, Ohtani Y, Nakamura J, Katayama T, Nakagawa T, Minami M, Satoh M: ATP induces leukemia inhibitory factor mRNA in cultured rat astrocytes. J Neuroimmunol 129: 43-50 (2002)

Watanabe T, Nakagawa T, Yamamoto R, Maeda A, Minami M, Satoh M: Involvement of glutamate receptors within the central nucleus of the amygdala in naloxone-precipitated morphine withdrawal-induced conditioned place aversion in rats. Jpn J Pharmacol 88: 399-406 (2002)

Yoshida K, Nakagawa T, Kaneko S, Akaike A, Satoh M: Adenosine 5'-triphosphate inhibits slow depolarization induced by repetitive dorsal root stimulation in substantia gelatinosa neurons of the adult rat spinal cord slices via P2Y purinoceptors. Neurosci Lett 320: 121-124 (2002)

2001年

Nakagawa T, Minami M, Satoh M: Up-regulation of RGS4 mRNA by opioid agonists in PC12 cells expressing cloned m- or k-opioid receptors. Eur J Pharmacol 433: 29-36 (2001)

Fukui M, Nakagawa T, Minami M, Satoh M: Involvement of b2-adrenergic and m-opioid receptors in antinociception produced by intracerebroventricular administration of a,b-methylene-ATP. Jpn J Pharmacol 86: 423-428 (2001)

Ozawa T, Nakagawa T, Shige K, Minami M, Satoh M: Changes in the expression of glial glutamate transporters in the rat brain accompanied with morphine dependence and naloxone-precipitated withdrawal. Brain Res 905: 254-258 (2001)

Nakagawa T, Ozawa T, Shige K, Yamamoto R, Minami M, Satoh M: Inhibition of morphine tolerance and dependence by MS-153, a glutamate transporter activator. Eur J Pharmacol 419: 39-45 (2001)

Fukui M, Nakagawa T, Minami M, Satoh M: Antinociceptive effects of intracerebroventricularly administered P2 purinoceptor agonists in the rat. Eur J Pharmacol 419: 25-31 (2001)

2000年

Nakagawa T, Masuda T, Watanabe T, Minami M, Satoh M: Possible involvement of the locus coeruleus in inhibition by prostanoid EP3 receptor-selective agonists of morphine withdrawal syndrome in rats. Eur J Pharmacol 390: 257-266 (2000)

1999年

Nakagawa T, Ozawa T, Minami M, Satoh M: Sensitization of the adenylyl cyclase system in cloned k-opioid receptor-transfected cells following sustained agonist treatment: a chimeric study using G protein ai2/aq subunits. Jpn J Pharmacol 81: 353-361 (1999)

Nakagawa T, Kaneko M, Inamura S, Satoh M: Intracerebroventricular administration of nocistatin reduces inflammatory hyperalgesia in rats. Neurosci Lett 265: 64-66 (1999)

Ozawa T, Nakagawa T, Minami M, Satoh M: Supersensitization of the adenylyl cyclase system in Chinese hamster ovary cells co-expressing cloned opioid receptors and Gz, a PTX-insensitive G protein. Neurosci Lett 267: 117-120 (1999)

1998年

Seki T, Minami M, Kimura C, Uehara T, Nakagawa T, Satoh M: Bremazocine recognizes the difference in four amino acid residues to discriminate between a nociceptin receptor and opioid receptors. Jpn J Pharmacol 77: 301-306 (1998)

Seki T, Minami M, Nakagawa T, Ienaga Y, Morisada A, Satoh M: DAMGO recognizes four residues in the third extracellular loop to discriminate between m- and k-opioid receptors. Eur J Pharmacol 350: 301-310 (1998)

1996年

Katsumata S, Ienaga Y, Minami M, Nakagawa T, Kanematsu K, Satoh M: Pharmacological characterization of KT-90 using cloned m-, d- and k-opioid receptors. Eur J Pharmacol 312: 349-355 (1996)

Minami M, Nakagawa T, Seki T, Onogi T, Aoki Y, Katao Y, Katsumata S, Satoh M: A single residue, Lys108, of the d-opioid receptor prevents the m-opioid-selective ligand [D-Ala2, N-MePhe4, Gly-ol5]enkephalin from binding to the d-opioid receptor. Mol Pharmacol 50: 1413-1422 (1996)

1995年

Katsumata S, Minami M, Nakagawa T, Iwamura T, Satoh M: Pharmacological study of dihydroetorphine in cloned m-, d- and k-opioid receptors. Eur J Pharmacol 291: 367-373 (1995)

Nakagawa T, Minami M, Kastumata S, Ienaga Y, Satoh M: Suppression of naloxone-precipitated withdrawal jumps in morphine-dependent mice by stimulation of prostaglandin EP3 receptor. Br J Pharmacol 116: 2661-2666 (1995)

Minami M, Onogi T, Nakagawa T, Katao Y, Aoki Y, Katsumata S, Satoh M: DAMGO, a m-opioid receptor selective ligand, distinguishes between m-and k-opioid receptors at a different region from that for the distinction between m- and d-opioid receptors. FEBS Lett 364: 23-27 (1995)

Onogi T, Minami M, Katao Y, Nakagawa T, Aoki Y, Toya T, Katsumata S, Satoh M: DAMGO, a m-opioid receptor selective agonist, distinguishes between m- and d-opioid receptors around their first extracellular loops. FEBS Lett 357: 93-97 (1995)

Katsumata S, Minami M, Nakagawa T, Satoh M: Intracisternal administration of interleukin-1b attenuates naloxone-precipitated withdrawal in morphine-dependent mice. Eur J Pharmacol 278: 143-150 (1995)