Division of Biomedical Sciences

Professor

Fumiyoshi YAMASHITA

1. Development of novel nano-DDSs for better therapeutic outcomes
2. Association analysis of pharmacokinetics and toxicokinetics of nano-DDSs with their physicochemical properties
3. Research on DDS technology for cell-based medicine

Associate Professor
Atsushi YONEZAWA

1. Clinical pharmacological research for a personalized treatment with therapeutic antibody drugs.
2. Involvement of renal organic cation transporters involved in the side effects of drugs
3. Identification of novel riboflavin transporter RFVT and pathophysiology of rare diseases BVVLS

Professor
Masahiro ONO

1. Development of molecular probes for the in vivo analysis of biological function, etiological mechanisms, and action mechanisms of drugs
2. Development of radiopharmaceuticals for functional diagnosis and radionuclide therapy
3. Clarification of the biological actions of trace metals and development of physiologically active metals complexes

Professor
Yoshinobu TAKAKURA

1. Development of drug delivery system using exosomes
2. Establishment of immunotherapy based on gene delivery technology
3. Development of delivery systems of proteins and nucleic acid drugs utilizing nucleic acid-based nanostructures
4. Development of multifunctional cell therapeutics for in vivo cell therapy

Professor
Shuji KANEKO

1. Physiology, pathology, molecular mechanisms, pharmacology, ligand screening and genome science with respect to the membrane transport proteins, especially toward TRP channels
2. The roles of neuron-glia-immune cell interaction in CNS pathology and drug action
3. Substantial background of pain and action mechanism of analgesics
4. Molecular and cellular mechanisms of drug actions and aversive effects

1. Reverse translational research for adverse effects of anti-cancer drugs: elucidation of the mechanisms and development of novel preventive and treatment strategies
2. Clinical and basic studies on Pharmacokinetics and Pharmacodynamics
3. Molecular and neural mechanisms underlying pathological pain and dysesthesia
4. Study of the pathogenic mechanism of Parkinson’s disease in order to identify a potential novel cure
5. Application of biomarkers to individualized pharmacotherapy